王志梅 - 东南大学 - 化学化工学院

个人简介

2001.9-2005.7 中国药科大学制药工程专业，获学士学位 2005.9-2008.7 中国药科大学药物分析专业，获硕士学位 2012.2-2016.12 中国药科大学制药工程专业，获博士学位 2008.7-至今东南大学药物研究中心，江苏省生物药物高技术研究重点实验室，东南大学分析测试中心，工程师

研究领域

铂类抗肿瘤药物的仪器分析

近期论文

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Wang ZM(王志梅), Yu HY, Gou SH, et al. Design, synthesis, and biological features of platinum(II) complexes with rigid steric hindrance [J]. Inorganic Chemistry, 2016, 55(9): 4519-4528. Wang ZM(王志梅), Wu M, Gou SH. Toward a better understanding of the oxaliplatin mode of action upon the steric hindrance of 1,2-diaminocyclohexane and its analogue [J]. Journal of Inorganic Biochemistry, 2016, 157: 1-7. Yu HY, Gou SH, Wang ZM(王志梅),et al. Toward overcoming cisplatin resistancevia sterically hindered platinum(II) complexes [J]. European Journal of Medicinal Chemistry, 2016, 114:141-152. Huang XC, Huang RZ, Gou SH, Wang ZM(王志梅), Liao ZX, and Wang HS. Combretastatin A-4 analogue: A dual-targeting and tubulin inhibitor containing antitumor Pt(IV) moiety with a unique mode of action.Bioconjugate Chemistry, 2016, 27(9): 2132-2148. Zhao J, WenYL, ZhangW, Zhao D, Fan A, Zhang YJ, Deng SH, Wang X, Wang ZM(王志梅), Gou SH, Chen XJ. Investigation on pharmacokinetics, tissue distribution and excretion of a novel platinum anticancer agent in rats by inductively coupled plasma mass spectrometry [J]. Xenobiotica, 2014, 44(8): 757-762. ZhaoJ, GouSH, Sun YY, Fang L, Wang ZM(王志梅). Antitumor platinum (II) complexes containing platinum based moieties of present platinum drugs and furoxan groups as nitric oxide donors: synthesis, DNA interaction and cytotoxicity [J]. Inorganic Chemistry, 2012, 51(19): 10317-10324. Zhao J, Gou SH,Sun YY, Yin RT, and WangZM(王志梅).Nitric oxide donors as potential anticancer agents [J].Chemistry-AEuropean Journal, 2012, 18(45): 14276-14281.