Zhao, Yunde - University of California, San Diego - Division of Biological Sciences

个人简介

Yunde Zhao received his Ph.D. in biochemistry from the University of Michigan and his postdoctoral training in plant genetics at the Salk Institute, where he was a Howard Hughes Medical Institute Fellow of the Life Sciences Research Foundation.

研究领域

Our research focuses on the plant hormone auxin, which regulates almost every aspect of plant growth and development. My laboratory mainly works on two areas of auxin biology: 1) auxin biosynthesis and its regulation, 2) the roles of auxin in axillary meristem development and plant organogenesis. We have elucidated the main auxin biosynthesis pathway in Arabidopsis and identified YUC flavin monooxygenases as key enzymes for auxin biosynthesis. We currently investigate the allosteric regulation of YUC enzymes and characterize the transcription factors that control the expression of YUC genes. We conducted a genetic screen for enhancers / suppressors of yuc mutants and uncovered a novel signaling pathway that is essential for the formation of lateral organs in Arabidopsis. We are continuing to clone and characterize additional yuc enhancers / suppressors to establish a genetic framework for plant organogenesis. We are also developing tools to spatially and temporally control auxin production.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Dai X., Zhang Y., Zhang D., Chen J., Gao X., Estelle M., and Zhao, Y. (2015) Embryonic lethality of Arabidopsis abp1-1 is caused by deletion of the adjacent BSM gene. Nature Plants, 9 NOVEMBER 2015 DOI:10.1038/NPLANTS.2015.183 Gao Y., Zhang Y., Zhang D., Dai X., Estelle M., and Zhao Y. (2015) Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development. PNAS 112, 2275–2280. PMID: 25646447 Zhao Y (2014) Auxin biosynthesis. The Arabidopsis Book, First published on June 13, 2014: e0173. doi: 10.1199/tab.0173. PMID: 24955076 Chen Q, Dai X, De-Paoli H, Cheng Y, Takebayashi Y, Kasahara H, Kamiya Y, and Zhao Y (2014) Auxin overproduction in shoots cannot rescue auxin deficiencies in Arabidopsis roots. Plant Cell Physiology 55(6):1072-9. PMID: 24562917 Gao Y and Zhao Y (2014) Self‐processing of ribozyme‐flanked RNAs into guide RNAs in vitro and in vivo for CRISPR‐mediated genome editing. Journal of Integrative Plant Biology. 56(4):343-9 PMID: 24373158