个人简介
1984年3月出生于湖南永州,湖南大学生物学院教授,博士生导师,副院长。化学生物传感与计量学国家重点实验室PI (2017)。教育部青年长江学者(2017),中国科协“青年人才托举工程”(2016),湖南省优秀博士学位论文(2015)。湖南师范大学获生物技术学士学位(2007年)、理学博士学位(2013年,导师:陈良碧、栾升(UCB)教授)。加州大学伯克利分校大数据分析方向访问学者(2017.12-2018.12,合作导师Devin Coleman-Derr)。以通讯作者或第一作者发表SCI源刊论文15篇,多篇论文入选ESI高被引论文,包括PNAS(4篇),PLOS Biology, Molecular Plant等。主持国家自然科学基金项目3项。 教育背景 2003-2007 湖南师范大学 生物技术专业 本科 2008-2013 湖南师范大学 硕博连读生,导师:陈良碧, 栾升教授 2017-2018 加州大学伯克利分校 生物信息与大数据,访问学者,合作导师:Devin Coleman-Derr 工作履历 PROFESSIONAL EXPERIENCE 2013- 2017 Associate Professor, Hunan University, Changsha, Hunan, China 2017- 2018 Research Professor, Hunan University, Changsha, Hunan, China 2018-now Professor, Hunan University, Changsha, Hunan, China
研究领域
以拟南芥、水稻和辣椒为材料,综合运用遗传、生化分析与检测、生物成像、生物信息和结构生物学等手段,围绕以下三个相互独立,但又紧密关联的方向开展工作:(1)细胞活动与环境适应性:围绕植物细胞如何根据其内外环境动态变化调控其细胞活动,并适应环境的相关科学问题进行系统探究。现阶段主要工作是解析受体蛋白激酶FERONIA在植物生长发育与逆境响应等调控中的信号网络;(2)优良农作物性状挖掘及新品种培育:将RALF多肽,FERONIA等在绿色、高产、优质中发挥关键作用的基因资源应用于水稻及辣椒等经济作物的品种培育和性状改良;(3)生物信息学与大数据:利用宏基因组学和大数据分析手段,研究RNA生物学、系统生物学、植物与微生物互作及植物功能基因的挖掘和进化等相关问题。
近期论文
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1.Yu F#, Shi J#, Zhou JY#, Gu JL, Chen QH, Li J, Cheng W, Mao DD, Tian LF, Buchanan B*, Li LG, Chen LB, Li DP*, Luan S* (2010) ANK6, a Mitochondrial Ankyrin Repeat Protein, is Required for Male-female Gamete Recognition in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America 107: 22332–22337. 2.Yu F, Qian LC, Nibau C, Duan QH, Kita D, Levasseur K, Li X, Lu CQ, Li H, Hou CC, Li LG, Buchanan BB*, Chen LB*, Cheung A, Li DP*, Luan S* (2012) FERONIA Receptor Kinase Pathway Suppresses Abscisic Acid Signaling in Arabidopsis by Activating ABI2 Phosphatase. Proceedings of the National Academy of Sciences of the United States of America 109: 14693-14698. ESI highly cited paper 3.Yu F, Li J, Huang Y, Liu L, Li DP*, Chen LB*, Luan S* (2014a) FERONIA Receptor Kinase Controls Seed Size in Arabidopsis thaliana. Molecular Plant 7:920-922. ESI highly cited paper 4.Yu F#, Tian W#, Luan S* (2014b) From Receptor-Like Kinases to Calcium Spikes: What Are the Missing Links? Molecular Plant 7:1501-1504. 5.Yu DS#, Yu F#, Du CQ, Li XS, Zhao XY*, Liu XM* (2015) RPN1a, a Subunit of the 26S Proteasome, Controls Trichome Development in Arabidopsis. Plant Physiology and Biochemistry 88:82-88. 6.Mao DD#, Yu F*#, Li J, Van de Poel B, Tan D, Li JL, Liu Y, Li XS, Dong MQ, Chen LB, Li DP, Luan S* (2015) FERONIA Receptor Kinase Interacts with S-adenosylmethionine Synthetase and Suppresses S-adenosylmethionine Production and Ethylene Biosynthesis in Arabidopsis. Plant, Cell & Environment 38:2566-2574. ESI highly cited paper 7.Yang T#, Wang L#, Li CY, Liu Y, Zhu SR, Qi YY, Liu XM, Lin QL*, Luan S, Yu F* (2015) Receptor Protein Kinase FERONIA Controls Leaf Starch Accumulation by Interacting with Glyceraldehyde-3-Phosphate Dehydrogenase. Biochemical and Biophysical Research Communications 465:77-82. 8.Chen J#, Yu F*#, Liu Y, Du CQ, Li XS, Zhu SR, Wang XC, Lan WZ, Rodriguez PL, Liu XM, Li DP, Chen LB, Luan S* (2016) FERONIA Interacts with ABI2-type Phosphatases to Facilitate Signaling Cross-talk Between Abscisic Acid and RALF Peptide in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America 113:E5519-E5527. ESI highly cited paper 9.Yu DS#, Li XS#, Zhao XY#, Du CQ, Chen J, Li CY, Sun MS, Wang L, Lin JZ, Tang DY, Yu F*, Liu XM* (2016) RPN1a Negatively Regulates ABA Signaling in Arabidopsis. Plant Physiology and Biochemistry 108:279-285. 10.Yu F, Luan S* (2016) Peptide Signaling in Plants: Finding Partners is the Key. Cell Research 26:755-756. 11.Du CQ#, Li XS#, Chen J#, Chen W, Li B, Li CY, Wang L, Li JL, Zhao XY, Lin JZ, Liu XM*, Luan S*, Yu F* (2016) Receptor Kinase Complex Transmits RALF Peptide Signal to Inhibit Root Growth in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America 13:E8326-E8334. ESI highly cited paper 12.Li CY#, Wang L#, Cui YC, He LM, Qi YY, Zhang JX, Lin JZ, Liao HD, Lin QL, Yang T, Yu F*, Liu XM* (2016) Two FERONIA Like Receptor (FLR) Genes are Required to Maintain Architecture, Fertility and Seed Yield in Rice. Molecular Breeding 36: 151-162. 13.Yu F (2017) Molecular Mechanism of Cross-talk Between Abscisic Acid and RALF Peptide in Arabidopsis. Science Foundation in China 4:50-50. 14.Liao HD, Zhang X, Tang RJ, Luan S*, Yu F* (2017) FERONIA Receptor Kinase at the Crossroad of Hormone Signaling and Stress Responses. Plant and Cell Physiology 58: 1143-1150. 15.Lu CQ#, Yu F#, Tian LF#, Huang XY, Tan H, Xie ZJ, Hao XH, Li DP*, Luan S*, Chen LB* (2017) RPS9M, a Mitochondrial Ribosomal Protein, Is Essential for Central Cell Maturation and Endosperm Development in Arabidopsis. Frontiers in Plant Science 8:2171. 16.Li CY#, Liu XM#, Qiang XN, Li XY, Li XS, Zhu SR, Wang L, Wang Y, Liao HD, Luan S, Yu F* (2018) EBP1 Nuclear Accumulation Negatively Feeds Back on FERONIA-Mediated RALF1 Signaling. PLOS Biology 16: e2006340.