黄晋 - 湖南大学 - 化学化工学院

个人简介

化学生物传感与计量学国家重点实验室/生物纳米与分子工程湖南省重点实验室/湖南大学化学化工学院教授，博士生导师，分析化学学科负责人，教育部青年长江学者，湖南省杰出青年基金获得者，湖南大学岳麓学者，主要研究兴趣是利用DNA分子进行材料构建、信息编码、逻辑计算、信号放大，以及生物医学方面的应用研究。先后主持和参与国家和省部级科研项目近20项，共发表研究论文近200篇，总引用次数超过9000次（H因子51），获发明专利8项。教育背景 2009-2011：美国佛罗里达大学联合培养博士 2005-2011：湖南大学化学化工学院理学博士 2001-2005：湖南大学化学化工学院理学学士工作履历 2019-至今：湖南大学化学化工学院教授 2015-2019：湖南大学化学化工学院副教授 2012-2015：湖南大学化学化工学院助理教授 2011-2017：湖南大学化学化工学院博士后

研究领域

利用DNA分子进行信息编码、逻辑计算、信号放大，以及在生物医学方面的应用研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Y. Chen, X. Liu, Y. Guo, S. Liu, J. Wang, X. He, X. Yang, K. Wang, J. Huang*. Tiny pH-resolved DNA nanospheres for cellular pyroptosis or apoptosis regulation. Nano Letters, 2024, DOI: 10.1021/acs.nanolett. 4c03937 S. Liu, J. Wang, Y. Chen, J. Fan, B. Du, R. Liu, X. Zhu, K. Wang, N. Xie*, J. Huang*. Modular assembled localized hybridization chain reaction for in situ mRNA amplified imaging. Nano Letters, 2024, 24, 11590-11598. Y. Chen, Y. Guo, J. Wang, R. Liu, X. Yang, K. Wang, Y. Pu*, H. Shi*, J. Huang*. Engineering self-catabolic DNAzyme nanospheres for synergistic anticancer therapy. Science China Chemistry, 2024, 67, 2412-2422. J. Li*, M. Chen, Q. Jiang, W. Zhang, Y. Lan, M. M. Ahmed, C. Ma, J. Huang*, Q. Xu*. Upgraded and light-up biosensing platform: entropy-driven catalysis circuit manipulates the configuration transformation of novel DNA silver nanoclusters on the graphene oxide surface. Analytical Chemistry, 2024, 96, 9209-9217. J. Li*, M. Chen, Q. Jiang, W. Zhang, S. Wang, J. Huang*, Q. Xu*. A highly cost-effective and sensitive biosensing platform: fuel-propelled DNA nanomachines modulate fluorescence switching of DNA. Microchemical Journal, 2024, 203, 110880. J. Li*, Q. Jiang, M. Chen, W. Zhang, R. Liu, J. Huang*, Q. Xu*. An attomolar-level electrochemical DNA biosensor based on target-triggered and entropy-driven catalytic ampliffcation integrated with AuNPs@ZIF-8 nanocomposites for oral cancer overexpressed 1 detection. Analytica Chimica Acta, 2024, 1287, 342055. J. Li*, X. Liu, J. Wang, Q. Jiang, M. Chen, W. Zhang, Y. Chen, Y. Pu*, J. Huang*. Self-assembled DNA nanospheres: design and applications. Chemistry, 2023, 5, 1882-1910. Z. Liu, N. Xie, J. Li, X. Fu, K. Wang, H. Shi*, J. Huang*. Self-priming DNA polymerization-propelled stochastic walkers on magnetic microbeads for amplified detection of miRNA. Analytical Chemistry, 2023, 95, 4529-4535. J. Wang, X. Fu, S. Liu, R. Liu, J. Li, K. Wang, J. Huang*. Catalyst-accelerated circular cascaded DNA circuits: simpler design, faster speed, higher gain. Small, 2023, 2205903. J. Wang, J. Li, Y. Chen, R. Liu, Y. Wu, J. Liu, X. Yang, K. Wang, J. Huang*. Size-controllable and self-assembled DNA nanosphere for amplified microRNA imaging through ATP-fueled cyclic dissociation. Nano Letters, 2022, 22, 8216-8223. J. Li, S. Liu, J. Wang, R. Liu, X. Yang, K. Wang, J. Huang*. Photocaged amplified FRET nanoflares: spatiotemporal controllable of mRNA-powered nanomachines for precise and sensitive microRNA imaging in live cells. Nucleic Acids Research, 2022, 50, e40. J. Xu, R. Jiang, Y. Feng, Z. Liu, J. Huang*, C. Ma*, K. Wang. Functional nucleic acid-based fluorescent probes for metal ion detection. Coordination Chemistry Reviews, 2022, 459, 214453. Y. Yang, T. Luo, Y. He, Z. Deng, J. Li, H. Liu, J. Nie, D. Wang, J. Huang*, S. Zhong*. Nanoflare couple：multiplexed mRNA imaging and logic-controlled combinational therapy. Analytical Chemistry, 2022, 94, 12204-12212. N. Xie, H. Wang, J. Li, K. Wang, J. Huang*. Dual amplification of bio-barcode and auto-cycling primer extention for highly sensitive detection of miRNA. Chemical Communications, 2022, 58, 10221-10224. S. Liu, Z. Liu, H. Wang, J. Wang, R. Liu, K. Wang, J. Huang*. A novel FRET-based dendritic hybridization chain reaction for tumor-related mRNA imaging. Chemical Communications, 2022, 58, 1414-1417. H. Wang, J. Wang, R. Liu, Z. Liu, K. Wang, J. Huang*. Auto-cycling primer extension for amplified microRNA detection. Chemical Communications, 2022, 58, 6020-6023. J. Li, J. Huang*. Fuel-powered DNA nanomachines for biosensing and cancer therapy. ChemPlusChem, 2022, 87, e202200098. Y. Ouyang, Y. Liu, Y. Deng, H. He, J. Huang*, C. Ma*, K. Wang. Recent advances in biosensor for DNA glycosylase activity detection. Talanta, 2022, 239, 123144. K. Quan, J. Wang, J. Li, K. Wang, J. Huang*. An endogenous miRNA-initiated hybridization chain reaction and subsequent DNAzyme activation for cellular theranostics. CCS Chemistry, 2021, 3, 3548-3558. L. Lan#, J. Huang#, M. Liu, Y. Yin, C. Wei, Q. Cai*, X. Meng*. Polymerization and isomerization cyclic amplification for nucleic acid detection with attomolar sensitivity. Chemical Science, 2021, 12, 4509-4518. J. Li, A. Wang, X. Yang, K. Wang, J. Huang*. Orderly-assembled, self-powered FRET flares for microRNA imaging in live cells. Analytical Chemistry, 2021, 93, 6270-6277. Q. Lin, S. Cai, B. Zhou, K. Wang, L. Jian*, J. Huang*. Dual-microRNA-regulation of singlet oxygen generation by DNA-tetrahedron-based molecular logic device. Chemical Communications, 2021, 57, 3873-3876. S. Cai, J. Wang, J. Li, B. Zhou, C. He, X. Meng*, J. Huang*, K. Wang. A self-assembled DNA nanostructure as a FRET nanoflare for intracellular ATP imaging. Chemical Communications, 2021, 57, 6257-6260. Y. Liu, Z. Liu, R. Liu, K. Wang, H. Shi*, J. Huang*. A MnO2 nanosheet-mediated photo-controlled DNAzyme for intracellular miRNA cleavage to suppress cell growth. Analyst, 2021, 146, 3391-3398. Y. Yang, Y. He, Z. Deng, J. Li, X. Li, J. Huang*, S. Zhong*. An autonomous self-cleavage DNAzyme walker for live cell microRNA imaging. ACS Applied Bio Materials, 2020, 3, 6310-6318. Y. Yang, Y. He, Z. Deng, J. Li, J. Huang*, S. Zhong*. Intelligent nanoprobe: acid-responsive drug release and in situ evaluation of its own therapeutic effect. Analytical Chemistry, 2020, 92, 12371-12378. J. Li, J.Wang, S. Liu, N. Xie, K. Quan, Y. Yang, X. Yang, J. Huang*, K.Wang*. Amplified FRET nanoflare: An endogenous mRNA-powered nanomachine for intracellular microRNA imaging. Angewandte Chemie International Edition, 2020,59,20104-20111. N. Xie, H. Wang, K. Quan, F. Feng*, J. Huang*, K. Wang*. Self-assembled DNA-based geometric polyhedrons: construction and applications. Trends in Analytical Chemistry, 2020, 126, 115844. K. Quan, C. Yi, X. Yang, X. He, J. Huang*, K. Wang*. FRET-based nucleic acid probes: basic designs and applications in bioimaging. Trends in Analytical Chemistry, 2020, 124, 115784. J. Wang, J. Li, S. Liu, X. Meng, X. Yang, J. Huang*, K. Wang*. An amplified AND logic platform for cell identification. Chemical Communications, 2020, 56, 11267-11270. Y. Wu, J. Li, K. Quan, X. Meng, Q. Guo, X. Yang, J. Huang*, K. Wang*. DNAzyme cascade for amplified detection of intracellular miRNA. Chemical Communications, 2020, 56, 10163-10166. A. Wang, Q. Lin, S. Liu, J. Li, J. Wang, K. Quan, X. Yang, J. Huang*, K. Wang. Aptamer-tethered self-assembled FRET-flares for micrRNA imaging in living cancer cells. Chemical Communications, 2020, 56, 2463-2466. Q. Lin, A.Wang, S. Liu, J. Li, J. Wang, K. Quan, X. Yang, J. Huang*, K. Wang. A DNA-tetrahedron-based molecular computation device for logic sensing of dual microRNAs in living cells. Chemical Communications, 2020, 56, 5303-5306. J. Li, S. Cai, B. Zhou, X. Meng, Q. Guo, X. Yang, J. Huang*, K. Wang*. Photocaged FRET nanoflares for intracelluar microRNA imaging. Chemical Communications, 2020, 56, 6126-6129. J. Li, K. Quan, Y. Yang, X. Yang, X. Meng, J. Huang*, K. Wang*. Engineering DNAzyme cascade for signal transduction and amplification. Analyst, 2020, 145, 1925-1932. N. Xie, S. Liu, H. Fang, Y. Yang, K. Quan, J. Li, X. Yang, K. Wang, J. Huang*. Three-dimensional molecular transfer from DNA nanocages to inner gold nanoparticle surfaces. ACS Nano, 2019, 13, 4174-4182. K. Quan, J. Li, J. Wang, N. Xie, Q. Wei, J. Tang, Xi. Yang, K. Wang, J. Huang*. Dual-microRNA-controlled double-amplified cascaded logic circuits for accurate discrimination of cell subtypes. Chemical Science, 2019, 10, 1442-1449. L. Lan, Q. Guo, H. Nie, C. Zhou, Q. Cai, J. Huang*, X. Meng*. Linear-hairpin variable primer RT-qPCR for microRNA. Chemical Science, 2019, 10, 2034-2043. Y. Yang, S. Zhong, K. Wang, J. Huang*. Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems. Analyst, 2019, 144, 1052-1072.