马骏 - 浙江大学

个人简介

1978.9-1982.7 北京大学生物学系本科 1982.8-1983.8 北京大学生物学系研究生（导师李汝祺教授） 1983.9-1990.7 美国哈佛大学生物化学和分子生物学系博士研究生（导师Mark Ptashne教授） 1989.7-1992.6 哈佛学会（Harvard Society of Fellows）青年会员 1992.7-2017.8 美国辛辛那提大学医学院儿童医院研究中心助理教授，副教授及教授 2017.9-至今浙江大学医学院，遗传学研究所教授

研究领域

系统发育遗传学

近期论文

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Ma, J., and Ptashne, M. (1987). Deletion analysis of GAL4 defines two transcriptional activating segments. Cell 48, 847-853. PMID: 3028647 Ma, J., and Ptashne, M. (1987). The carboxy terminal 30 amino acids of GAL4 are recognized by GAL80. Cell 50, 137-142. PMID: 3297349 Ma, J., and Ptashne, M. (1987). A new class of yeast transcriptional activators. Cell 51, 113-119. PMID: 3115591 Ruden, D., Ma, J., and Ptashne, M. (1988). No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene. Proc. Natl. Acad. Sci. USA 85, 4262-4266. PMID: 3132708; PMCID: PMC280407 Ma, J., Przibilla, E., Hu, J., Bogorad, L., and Ptashne, M. (1988). Yeast activators stimulate plant gene expression. Nature 334, 631-633. PMID: 3165494 Sadowski, I., Ma, J., Triezenberg, S., and Ptashne, M. (1988). GAL4-VP16 is an unusually potent transcriptional activator. Nature 335, 563-564. PMID: 3047590 Ma, J., and Ptashne, M. (1988). Converting a eukaryotic transcriptional inhibitor into an activator. Cell 55, 443-446. PMID: 3180218 Driever, W., Ma, J., Nusslein-Volhard, C., and Ptashne, M. (1989). Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences. Nature 342, 149-154. PMID: 2509940 Ruden, D., Ma, J., Li, Y., Wood, K., and Ptashne, M. (1991). Generating yeast transcriptional activators containing no yeast protein sequences. Nature 350, 250-252. PMID: 2005981 Dasmahapatra, B., DiDomenico, B., Dwyer, S., Ma, J., Sadowski, I., and Schwartz, J. (1992). A novel genetic system to study a proteolytic enzyme. Proc. Natl. Acad. Sci. USA 89, 4159-4162. PMID: 1570342; PMCID: PMC525652 Ma, J. (1992). Detecting interactions between eukaryotic proteins in bacteria. Gene Expression 2, 139-146. PMID: 1633437 Lehming, N., Thanos, D., Brickman, J., Ma, J., Maniatis, M., and Ptashne, M. (1994). A HMG-like protein that can switch a transcriptional activator to a repressor. Nature 371, 175-179. PMID: 8072548 Ma, X., Yuan, D., Diepold, K., Scarborough, T., and Ma, J. (1996). The Drosophila morphogenetic protein Bicoid binds DNA cooperatively. Development 122, 1195-1206. PMID: 8620846 Shaw, S. P., Wingfield, J., Dorsey, M. J., and Ma, J. (1996). Identifying a species-specific region of yeast TFIIB in vivo. Molecular and Cellular Biology 16, 3651-3657. PMID: 8668181; PMCID: PMC231360 Yuan, D., Ma, X., and Ma, J. (1996). Sequences outside the homeodomain of Bicoid are required for protein-protein interaction. J. Biol. Chem. 271, 21660-21665. PMID: 8702955 Shaw, S. P., Carson, D. J., Dorsey, M. J., and Ma, J. (1997). Mutational studies of yeast TFIIB in vivo reveal a functional surface important for gene activation. Proc. Natl. Acad. Sci. USA 94, 2427-2432. PMID: 9122211; PMCID: PMC20104 Ma, X., Yuan, D., Scarborough, T., and Ma, J. (1999). Contribution to gene activation by multiple functions of Bicoid. Biochem. J. 338, 447-455. PMID: 10024522; PMCID: PMC1220072 Yuan, D., Ma, X., and Ma, J. (1999). Recognition of multiple patterns of DNA sites by the Drosophila homeodomain protein Bicoid. J. Biochem. 125, 809-817. PMID: 10101296 Zhang, D., Dorsey, M. J., Voth, W. P., Carson, D. J., Zeng, X., Stillman, D. J., and Ma, J. (2000). Intramolecular interaction of yeast TFIIB in transcriptional Control. Nucl. Acids Res. 28, 1913-1920. PMID: 10756191; PMCID: PMC103289 Dave, V., Zhao, C., Yang, F., Tung, C.-S., and Ma, J. (2000). Reprogrammable recognition codes in Bicoid homeodomain-DNA interaction. Mol. Cell. Biol. 20, 7673-7684. PMID: 11003663; PMCID: PMC86337 Zhao, C., Dave, V., Yang, F. Scarborough, T., and Ma, J. (2000). Target selectivity of Bicoid is dependent on non-consensus site recognition and protein-protein interaction. Mol. Cell. Biol. 20, 8112-8123. PMID: 11027281; PMCID: PMC86421 Zhao, C., York, A., Yang, F., Forsthoefel, D. J., Dave, V., Fu, D., Zhang, D., Corado, M. S., Small, S., Seeger, M. A., and Ma, J. (2002). The activity of the Drosophila morphogenetic protein Bicoid is inhibited by a domain located outside its homeodomain. Development 129, 1669-1680. PMID: 11923203 Zhang, D., Carson, D. J., and Ma, J. (2002). The role of TFIIB-RNA polymerase II interaction in start site selection in yeast cells. Nucl. Acids Res. 30, 3078-3085. PMID: 12136090; PMCID: PMC135743