Lu, Xiaonan - University of British Columbia - faculty of land and food systems

个人简介

I am from Tianjin, China. After study in Tianjin No.1 Middle School (1997-2003), I received my B.S. (Food Science) from Ocean University of China in 2007 and Ph.D. (Food Science with minor in Analytical Chemistry) from Washington State University in 2011. I was a postdoctoral fellow in the College of Veterinary Medicine at Washington State University before I joined in UBC as Assistant Professor in January 2013, leading UBC Food Safety & Health Engineering Laboratory. I received tenure with promotion to Associate Professor in June 2017. I am also the adjunct professor at UBC Department of Chemistry, Microsystems and Nanotechnology (MiNa) Group, as well as UBC BioProducts Institute.

研究领域

The Lu’s Food Safety & Health Engineering Lab at UBC works on genomics, metabolomics, transcriptomics, and proteomics along with nanotechnology to investigate critical scientific questions in food science. We have interest in developing innovative and rapid sensing, instrumentation systems and detection methods for ensuring food safety as well as preventing food bioterrorism and fraud. We also apply molecular biology and genomic approaches to investigate stress response and pathogenesis of microorganisms that post threats to agri-food system and public health. Recently, we have started the investigation of the interaction between food microbiota/components and gut microbiota. Our current research is focused on five major directions: (1) Developing nano-biosensor and nano-based single-molecule biophotonics coupled with various separation techniques to rapidly detect chemical and microbiological hazards in food systems (2) Campylobacter-associated food safety (3) Food microbiology, including detection and molecular characterization of foodborne pathogens, evaluation of intervention technologies to reduce pathogens in food systems, investigation of the evolution of bacterial antibiotic resistance, assessment of bacterial biofilms, and study of bacterial response due to environmental stresses (4) Interaction between food components/diet pattern and human gut, such as gut microbiome and gut diseases (e.g., inflammatory bowel disease, gut wounds, and colorectal cancer) (5) Detection of food fraud and adulteration; identification of food mislabelling

近期论文

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Ma L.‡, Petersen M.‡, Lu X.*, Detection and antibiotic resistance determination of Campylobacter bacteria in milk using colorimetric-based microfluidic “lab-on-a-chip” device. Submitted. Ma L.‡, Chou K.C., Lu X.*, 2019. Deciphering the antibiotic resistance mechanism of Campylobacter using confocal micro-Raman spectroscopy. Submitted. Ma L.‡, Yuan X.‡, Chen L.‡, Chou K.C., Konkel M.E., Lu X.*, Modelling of tetracycline-resistance gene transfer from Campylobacter jejuni to human gut microbiota. Submitted. Hakeem M.‡, Nilghaz A.‡, Seah K.‡, Lu X.*. The release of zinc Ions from functionalized absorbing pads of active packaging can control Campylobacter jejuni contamination in raw chicken products. Submitted. Hakeem M.‡, Feng J.‡, Ma L.‡, Lu X.*. Whole transcriptome sequencing analysis of antimicrobial synergism of plant-based antimicrobials and zinc oxide nanoparticles against C. jejuni. Submitted. Han L.‡, Feng J.‡, Ma L.‡, Delaquis P., Lu X.*, Rapid determination of viable but non-culturable Escherichia coli O157:H7 and Salmonella Enteritidis in fresh produce by loop-mediated isothermal amplification coupling propidium monoazide treatment. Submitted. Wang K.‡, Zhang H.‡, Feng J.‡, Ma L.‡, de la Fuente-Núñez C., Wang S., Lu X.*, Antibiotic resistance of lactic acid bacteria isolated from dairy products in Tianjin, China. Submitted. Zhao L., Wang K.‡, Yan C., Xiao J., Wu H., Zhang H., Zhang X., Zhang C., Hu Y.‡, Lu X.*, Zheng W., A PCR-based lateral flow assay for the detection of turkey ingredient in food products. Submitted. 100. Hu Y.‡, Lu X.*, Simple sample-to-answer hybrid polymer/paper microfluidic device for the authentication of pomegranate juice. Submitted. Hu Y.‡, Huang S.‡, Lu X.*, Identification of seafood species using bench-top and portable Raman spectroscopy and chemometric models. Submitted. Hu Y.‡, Quilliam M., Wang S., Lu X.*, Quantification of domoic acid in shellfish using 1H nuclear magnetic resonance spectroscopy. Submitted. Hu Y.‡, Wu H., Li Z., Zheng W., Lu X.*, Application of two-dimensional gas chromatography-quadrupole mass spectrometry to determine geographical origins and harvesting seasons of orange used for juice production. Submitted. Zhao L., Hu Y.‡, Liu W., Wu H., Xiao J., Zhang C., Zhang H., Zhang X., Song Y., Liu J., Lu X.*, Zheng W., Identiﬁcation of camel species in food products by a nucleic acid-based lateral flow immunoassay. Submitted. Feng S.‡, Choi J.R.‡, Liu X.‡, Hu Y.‡, Lu X.*, Detection of melamine using textile-based molecularly imprinted polymers chemosensor. Submitted. An S., Huang Q., Hou F., Chen P., Pan H., Zhang L., Zhao Y., Lu X., Zhang X., Cerium-doped indium oxide transparent electrode for semi-transparent planar perovskite solar cells. Submitted. Nilghaz A.‡, Wang K.‡, Lu X.*, Development of paper-based rapid detection methods for food safety and quality analysis – current status and future trends. Submitted. Huang W., Hua M.Z.‡, Li S.‡, Chen K., Lu X.*, Wu D., Exploration of fruit texture by atomic force microscopy. Submitted. Jia M., Liu Z., Wu C., Zhang Z., Ma L.‡, Lu X.*, Mao Y., Zhang H., 2019. Detection of Escherichia coli O157:H7 and Salmonella enterica serotype Typhimurium based on cell elongation induced by beta-lactam antibiotics. Analyst, in press. DOI: 10.1039/C9AN00569B Hakeem M.J.‡, Asseri K.A., Ma L.‡, Chou K.C., Konkel M.E., Lu X.*, 2019. A novel mathematical model for studying antimicrobial interactions against Campylobacter jejuni. Frontiers in Microbiology, 10, 1038. DOI: 10.3389/fmicb.2019.01038 Nilghaz A.‡, Liu X.‡, Ma L.‡, Huang Q., Lu X.*, 2019. Development of fabric-based microfluidic devices by wax printing. Cellulose, 26, 3589-3599.