Chen, Sijie - Karolinska Institute -

个人简介

Dr Sijie Chen is an Assistant Professor at Ming Wai Lau Centre for Reparative Medicine, KI, in Hong Kong. Dr Sijie Chen received her BSc in Biology from Wuhan University in 2009 and PhD in Bioengineering from Hong Kong University of Science and Technology (HKUST) in 2013, under the supervision of Prof Ben Zhong Tang. She worked as a Postdocal Fellow in HKUST and then as an Endeavour Fellow in University of Melbourne and a visiting scientist in Walter and Eliza Hall Institute of Medical Research. She joined Prof Ana Teixeira’s group as a Postdoc in the Division of Biomaterials and Regenerative Medicine at the Department of Medical Biochemistry and Biophysics in Karolinska Institutet (KI) since late 2015. She was earlier working on fluorescent biosensors, fluorescence imaging and nanomaterials. She has authored and co-authored ~ 40 scientific papers in related areas.

研究领域

Her current research interests focus on the development of new luminescent materials and novel methods for studying the biological events, especially fluorescent tools for mechanobiology research.

近期论文

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S. Xie , A.Y.H. Wong, R.T.K. Kwok, Y. Li, H. Su, J.W.Y. Lam, S. Chen*, B.Z. Tang*. "Fluorogenic Ag+–Tetrazolate Aggregation Enables Efficient Fluorescent Biological Silver Staining." Angew. Chem. Int. Ed., 2018, 57, 5750. B. Situ#, S. Chen#, E. Zhao, C. W. T. Leung, Y. Chen, Y. Hong, J. W. Y. Lam, Z. Wen, W. Liu, W. Zhang, L. Zheng, B. Z. Tang. “Real-Time Imaging of Cell Behaviors in Living Organisms by a Mitochondria Targeting AIE Fluorogen.” Adv. Funct. Mater., 2016, 26, 7132. S. Chen, Y. Hong, Y. Liu, J. Liu, C. W. T. Leung, M. Li, R. T. K. Kwok, E. Zhao, J. W. Y. Lam, Y. Yu, B. Z. Tang. “Full-Range Intracellular pH Sensing by an Aggregation-Induced Emission-Active Two-Channel Ratiometric Fluorogen.” J. Am. Chem. Soc., 2013, 135, 4926. S. Chen#, J. Liu#, Y. Liu, H. Su, Y. Hong, C. K. W. Jim, R. T. K. Kwok, N. Zhao, W. Qin, J.W.Y Lam, K. S. Wong, B. Z. Tang. “An AIE-active hemicyanine fluorogen with stimuli-responsive red/blue emission: extending the pH sensing range by “switch + knob” effect.” Chem. Sci., 2012, 3, 1804.