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个人简介

教育背景 2012年6月-2014年6月:博士研究生、康奈尔医学院休斯顿卫理公会研究所,沈海法教授 2010年9月-2014年6月:博士研究生、无机化学,中山大学,毛宗万教授 2007年9月-2010年6月:硕士研究生、无机化学,湘潭大学,谭黎峰教授 2003年9月-2007年6月:学士、应用化学,湖南科技大学, 周智华教授 科研/工作经历 2017年10月-至今:研究员、中国科学院大学温州研究院 2017年10月-至今:研究员、温州医科大学眼视光学院 (生物医学工程学院)、眼视光附属医院 2014年6月-2017 年6月:博士后、康奈尔医学院休斯顿卫理公会研究所,沈海法教授 2012年6月-2014 年6月:助理研究员、康奈尔医学院休斯顿卫理公会研究所,沈海法教授

研究领域

智能化纳米材料递送基因药物 药物自组装的自我递送 肿瘤微环境响应的多级靶向递送体系 功能化水凝胶的生物医药应用 纳米免疫治疗

近期论文

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Hou, J., Wang, S.,* Wang, B., He, X., Yoon, J.,* Shen, J.,* Sulfur-based Fluorescent Probes for HOCl: Mechanisms, design, and applications, Coordination Chemistry Reviews, 2021. Accepted. Yi,Q., He, J., Fu, X., Ying, J., Gong, L., Shen, J.,* He, X., Carbazole-based chemosensor for highly sensitive and selective bioimaging identification of hydrazine in multiple model systems via ratiometric and colorimetric, Dyes and Pigments 2021, 196, 109816 Qi, X., Tong, X., Pan, W., Zeng, Q., You, S., Shen, J.,* Recent advances in polysaccharide-based adsorbents for wastewater treatment, Journal of Cleaner Production, 2021, 128221. Xiong, W., Qi, Lin., Si, D., Jiang, X., Liu, Y., Zheng, C., Li, Y.,* Shen, J.,* Zhou, Z.,* Effective Tumor Vessel Barrier Disruption Mediated by Perfluoro-N-(4-methylcyclohexyl) Piperidine Nanoparticles to Enhance the Efficacy of Photodynamic Therapy, Nanoscale, Accepted. Jiang, N., Zhou, Z., Xiong, W., Chen, J., Shen, J.,* Li, R.,* Ye R.,* Tumor microenvironment triggered local oxygen generation and photosensitizer release from manganese dioxide mineralized albumin-ICG nanocomplex to amplify photodynamic immunotherapy efficacy, Chinese Chemical Letters, Accepted. Wang, Q., Lv, H., Ding, F., Jin, Z., Liu, Y., Sun, X., Ye, L., Xu, W., Mu, C., Shen, J.,* He, X.,* Multifunctional chemosensor for tracing Ga(III), hypochlorite and pH change with bioimaging in living cells, Pseudomonas aeruginosa and Zebrafish, Sensors and Actuators B: Chemical, 2021, 130346. Mai, J., Li, Z., Xia, X., Zhang, J., Li, J., Liu, H., Shen, J., Ramirez, M., Li, F., Li, Z., Yokoi, K., Liu, X., Mittendorf, E., Ferrari, M., Shen, H.,* Synergistic Activation of Antitumor Immunity by a Particulate Therapeutic Vaccine, Advanced Science, 2021, 2100166. Chen, H., Zhou, Z., Li, Z., He, X., Shen, J.,* Highly Sensitive Fluorescent Sensor Based on Coumarin Organic Dye for Pyrophosphate Ion Turn-on Biosensing in Synovial Fluid, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 119792. Ding, F., Wen, H., Zhuo, R., Li, J., Zheng, H., Deng, R., Shen, J.,* He, X.,* A Novel Ratiometric and Colorimetric Chemosensor for Highly Sensitive, Selective and Ultrafast Tracing of HClO in Live Cells, Bacteria and Zebrafish, Analytica Chimica Acta, 2021, 338472. Qi, X., Pan, W., Tong, X., Gao, T., Xiang, Y., You, S., Mao, R., Chi, J., Hu, R., Zhang, W.,* Deng, H.,* Shen, J.,* ε‑Polylysine-stabilized agarose/polydopamine hydrogel dressings with robust photothermal property for wound healing, Carbohydrate Polymers, 2021, 118046 Zhang, H., Zhang, D., Shen, J.,* Mao, Z.-W.,* 3D CoPt nanostructures hybridized with iridium complexes for multimodal imaging and combined photothermal-chemotherapy, Journal of Inorganic Biochemistry, 2021, 219,111429. Chen, G., Qian, Y., Zhang, H., Ullah, F., He, X., Zhou, Z., Fenniri, H.,* Shen, J.,* Advances in Cancer Theranostics Using Organic-Inorganic Hybrid Nanotechnology, Applied Materials Today, 2021, 23, 101003. Qian, Y., Xu, C., Xiong, W., Jiang, N., Zheng, Y., He, X., Ding, F., Lu, X.,* Shen, J.,* Dual Cross-Linked Organic-inorganic Hybrid Hydrogels Accelerate Diabetic Skin Wound Healing, Chemical Engineering Journal, 2021, 417, 129335. He, X., Ding, F., Sun, X., Zheng, Y., Xu, W., Ye, L., Chen, H.*, Shen, J.*, Reversible Chemosensor for Bioimaging and Biosensing of Zn(II) and hpH in Cells, Larval Zebrafish, and Plants with Dual-Channel Fluorescence Signals, Inorganic Chemistry, 2021. https://doi.org/10.1021/acs.inorgchem.0c03456 He, X., Dai, L., Wen, H., Xu, C., Xu, W., Ye, L., Sun, X., Song, W.*, Shen, J.*, Reaction-based Chemosensor as Dual-channel Indicator for Visualizing and Bioimaging of Exogenous Hypochlorite Concentrations in Living Cells, Pseudomonas aeruginosa, and Zebrafish, Analytica Chimica Acta, 2021. 338391. Zheng, Q., Ding, F., Hu, X., Feng, J., Shen, J.,* He, X. *, ESIPT-based Fluorescent Probe for Bioimaging and Identification of Group IIIA Ions in Live Cells and Zebrafish,Bioorganic Chemistry, 2021, 109, 104746. Yu, Q., Ding, F., Shen, J.,* He, X.*, A Newly Nitrobenzoxadiazole (NBD)-fused Reversible Fluorescence Probe for pH Monitoring and Application in Bioimaging, Talanta, 2021, 122218. Xiong, W., Zhou, Z., Qi, L., Jiang, N., Zhao, Q., Chen, L.,Jiang, X., Li, Y., Shen, J.* Metformin Liposomes Mediated PD-L1 Downregulation for Amplifying the Photodynamic Immunotherapy Efficacy, ACS Applied Materials & Interfaces, 2021, 10.1021/acsami.0c21743. Shen, L., Lu, Q., Chen, Q., Li, Y., Wu, X., Shen, J.* Constructing Cylindrical Nanostructures Via the Directional Morphology Evolution Induced by Seeded Polymerization, Macromolecular Rapid Communications, 2021, https://doi.org/10.1002/marc.202100001. Zeng, Q., Qian, Y., Huang, Y., Ding, F., Qi, X., Shen, J.* Polydopamine Nanoparticle-Dotted Food Gum Hydrogel with Excellent Antibacterial Activity and Rapid Shape Adaptability for Accelerating Bacteria-Infected Wound Healing, Bioactive Materials, 2021, 6, 2647-2657

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