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个人简介

张平玉,博士,英国皇家科学会‘牛顿学者’,硕士生导师,自2010年开始致力于金属配合物及其修饰的复合纳米材料用于肿瘤治疗与诊断的研究,2015年荣获英国皇家会牛顿基金资助,在英国华威大学Peter J. Sadler院士课题组学习工作2年,从事光活化金属配合物用于耐药菌的光活化治疗和细胞内光催化机理的研究。2017年9月,海外高层次孔雀人才引进深圳大学化学与环境工程学院,开始着手研究金属药物、生物传感、分子影像在肿瘤的治疗与诊断方面的应用。 2021/01-至今: 深圳大学(Shenzhen University),化学与环境工程学院,副教授,研究员 2017/09-2020/12: 深圳大学(Shenzhen University),化学与环境工程学院,助理教授,副研究员 2015/10-2017/09: 英国华威大学(University of Warwick),牛顿高级研究学者(Newton Felllow),合作导师:Peter J. Sadler(英国皇家院士和爱丁堡皇家院士) 2010/09-2015/07: 中山大学(Sun Yat-sen University),博士,导师:计亮年院士和巢晖教授

研究领域

金属药物的抗肿瘤活性的研究 光活化治疗和细胞内光催化机理的研究 声动力疗法的探究 金属药物在分子影像方面的应用 金属药物复合纳米材料用于肿瘤治疗与诊断的研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

C. Liang, J. Xie, S. Luo, C. Huang, Q. Zhang, H. Huang, P. Y. Zhang*, A Highly Potent Ruthenium(II)-Sonosensitizer and Sonocatalyst for in Vivo Sonotherapy. Nature Communications, 2021, 12, 5001. J. Xie,‡ C. Liang,‡ S. Luo, Z. Pan, Y. Lai, J. He, H. Chen, Q. Ren,* H. Huang,* Q. Zhang, P. Y. Zhang*, Water-Soluble Iridic−Porphyrin Complex for Non-invasive Sonodynamic and Sono-oxidation Therapy of Deep Tumors. ACS Appl. Mater. Interfaces, 2021, 13, 27934−27944. Q. Sun, Y. Wang, Q. X. Fu, A. Ouyang, S. S. Liu, Z. Y. Wang, Z. J. Su, J. X. Song, Q. L. Zhang, P. Y. Zhang,* D. S. Lu,* Sulfur-Coordinated Organoiridium(III) Complexes Exert Breast Anticancer Activity via Inhibition of Wnt/b-Catenin Signaling, Angew. Chem. Int. Ed., 2021, 133, 4891-4898. C. Imberti,‡ P. Y. Zhang,‡* H. Y. Huang,* P. J. Sadler,* New Designs for Phototherapeutic Transition Metal Complexes. Angew. Chem. Int. Ed., 2020, 59, 61-73. C. Huang, T. X. Li, J. Y. Liang, H. Y. Huang,* P. Y. Zhang,* Samya Banerjee*, Recent advances in endoplasmic reticulum targeting metal complexes. Coord. Chem. Rev., 2020, 408, 213178 . P. Y. Zhang, H. Y. Huang,* S. Banerjee, G. J. Clarkson, C. Ge, C. Imberti, P. J. Sadler,* Nucleus-Targeted Organoiridium–Albumin Conjugate for Photodynamic Cancer Therapy. Angew. Chem. Int. Ed., 2019, 58, 2350-2354. P. Y. Zhang,‡ C. K. C. Chiu,‡ H. Y. Huang, Y. P. Y. Lam, A. Habtemariam, T. Malcomson, M. J. Paterson, G. J. Clarkson, P. B O'Connor,* H. Chao,* P. J Sadler,* Organo-iridium photosensitizers can induce specific oxidative attack on proteins in cancer cells, Angew Chem. Int. Ed., 2017, 56, 14898. S. Ye,‡ F. Luo,‡ T. Xu,‡ P. Y. Zhang,* H. Shi, S. Qin, J. Wu, C. He, X. Ouyang, Q. Zhang,* J. Liu,* X. Sun*, Boosting the alkaline hydrogen evolution of Ru nanoclusters anchored on B/N–doped graphene by accelerating water dissociation, Nano Energy, 2019, 104301. Y. Wang, H. Huang, G. Chen, H. Chen, T. Xu, Q. Tang, H. L. Zhu*, Q. L. Zhang and P. Y. Zhang,* A novel iridium (III) complex for sensitive HSA phosphorescence staining in proteome research, Chem. Commun., 2018, 54, 3282-3285. C. Ge,‡ J. Y. Zhu,‡ A. Ouyang,‡ N. Lu, Y. Wang, Q. L. Zhang, P. Y. Zhang,* Near-infrared phosphorescent terpyridine osmium(II) photosensitizer complexes for photodynamic and photooxidation therapy, Inorg. Chem. Front., 2020, 7, 4020-4027.

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