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个人简介

吴钰周,华中科技大学化学与化工学院教授,博士生导师。先后于浙江大学、新加坡国立大学、和德国乌尔姆大学获得学士、硕士和博士学位。2013年5月-2016年9月先后担任德国乌尔姆大学和马普高分子研究所课题组长,2016年9月起任华中科技大学化学与化工学院教授,兼任马普高分子研究所课题组长,2019年任国家重点研发计划青年项目首席科学家。2019年吴钰周教授课题组被遴选为德国马普学会国际伙伴研究小组。 教育经历 2010.62013.5 乌尔姆大学理学博士学位研究生(博士)毕业 2008.82011.5 新加坡国立大学理学硕士学位研究生(硕士)毕业 2004.92008.6 浙江大学本科(学士) 工作经历 2016.9至今 华中科技大学化学与化工学院教授 2016.52016.8 德国马普高分子研究所课题组长 2013.52016.3 德国乌尔姆大学课题组长

研究领域

人工酶合成生物学 DNA折纸术 复合生物高分子材料 纳米医药及靶向药物载体 智能生物纳米材料

近期论文

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Ningning Sun, Jianjian Huang, Junyi Qian, Taiping Zhou, Juan Guo, Langyu Tang, Wentao Zhang, Yaming Deng, Weining Zhao, Guojiao Wu, Rongzhen Liao, Xi Chen*, Fangrui Zhong* & Yuzhou Wu*, Enantioselective [2+2]-cycloadditions with triplet photoenzymes, Nature, 2022, https://doi.org/10.1038/s41586-022-05342-4 Longjie Li, Kejun Dong, Xinyu Wange, Meizhou Zhang, Jun Li, Andreas K. Nussler, Xianjin Xiao, Hongbo Wang* and Yuzhou Wu*, DNA origami‐based nano‐hunter enriches low‐abundance point mutations by targeting wild-type gene segments. Chinese Chemical Letters, 2022, 33, 2052. Huaibin Yu, Shuangshuang Wang, Jianjian Huang, Yu Fu, Manfred Wagner, Tanja Weil, Fangrui Zhong, Weining Zhao*, and Yuzhou Wu*, Light-Controlled Traceless Protein Labeling via Decaging Thio-o-naphthoquinone Methide Chemistry, Org. Lett. 2022, 24, 6816. Yiwei Shi, Xuemei Xu, Huaibin Yu, Zian Lin, Honghua Zuo, and Yuzhou Wu*, Defined positive charge patterns created on DNA nanostructures determine cellular uptake efficiency. Nano Lett. 2022, 22, 5330. Jingyang Qin,Tong Zhou,Taiping Zhou,Langyu Tang,Honghua Zuo,Huaibin Yu,Guojiao Wu,Yuzhou Wu,Rong-Zhen Liao*,Fangrui Zhong*,Catalytic Atroposelective Electrophilic Amination of Indoles, Angew. Chem. Int. Ed. 2022, e202205159. Huaibin Yu,Jiayi Feng,Fangrui Zhong,Yuzhou Wu*, Chemical Modification for the “Off-/On” Regulation ofEnzyme Activity. Macromol. Rapid Commun.2022, 43, 2200195. Qiuyue Ding, Tingfang Sun, Weijie Su, Xirui Jing, Bing Ye, Yanlin Su, Lian Zeng,Yanzhen Qu, Xu Yang, Yuzhou Wu, Zhiqiang Luo, and Xiaodong Guo*, Bioinspired Multifunctional Black Phosphorus Hydrogelwith Antibacterial and Antioxidant Properties: A StepwiseCountermeasure for Diabetic Skin Wound Healing, Adv. Healthcare Mater. 2022, 11, 2102791. Boyang Hu, Ruijie Liu, Qingyue Liu, Zi’an Lin, Yiwei Shi, Jun Li, Lijun Wang, Longjie Li,* Xianjin Xiao* and Yuzhou Wu*, Engineering surface patterns on nanoparticles: new insights into nano-bio interactions. J. Mater. Chem. B, 2022, 10, 2357. Yaming Deng, Quan Zhou, Yuzhou Wu, Xi Chen*, Fangrui Zhong*, Properties and Mechanisms of Flavin-Dependent Monooxygenases and Their Applications in Natural Product Synthesis. Int. J. Mol. Sci. 2022, 23, 2622. Liandong Feng, Li Yang, Longjie Li, Junying Xiao, Nana Bie, Chao Xu, Jun Zhou, Hongmei Liu, Lu Gan, Yuzhou Wu*, Programmed albumin nanoparticles regulate immunosuppressive pivot to potentiate checkpoint blockade cancer immunotherapy, Nano Research, 2022, 15, 593-602. Liandong Feng, Shanshan Wu, and Yuzhou Wu*, Intracellular bottom-up Synthesis of Ultrasmall CuS Nanodots in Cancer Cells for Simultaneous Photothermal Therapy and COX-2 Inactivation, Adv. Funct. Mater., 2021, 31, 2101297 Colette J. Whitfield, Meizhou Zhang, Pia Winterwerber, Yuzhou Wu*, David Y. W. Ng*, and Tanja Weil* Functional DNA–Polymer Conjugates, Chem. Rev. 2021, 121, 11030. Yu Fu,# Jian Huang,# Yuzhou Wu,* Xiaohong Liu,* Fangrui Zhong,* and Jiangyun Wang*, “Biocatalytic Cross-Coupling of Aryl Halides with a Genetically Engineered Photosensitizer Artificial Dehalogenase” J. Am. Chem. Soc. 2021, 143, 617. Xunbo Lu, Yulong Bai, Jingyang Qin, Nan Wang, Yuzhou Wu,* and Fangrui Zhong*, “Alleviating Catalyst Decay Enables Efficient Intermolecular C(sp3)−H Amination under Mechanochemical Conditions” ACS Sustainable Chem. Eng, 2021, 9, 1684-1691. Shengze Xiao Long Mao, Junying Xiao, Yuzhou Wu, Hongmei Liu*, Eur. J. Pharmacol. 2021, 902, 174120. Jin Liu, Liandong Feng, Yuzhou Wu*, Enzymatically synthesised MnO2 nanoparticles for efficient near-infrared photothermal therapy and dual-responsive magnetic resonance imaging, Nanoscale, 2021, 13, 11093. Jin Liu, Meizhou Zhang, Yuzhou Wu*, In situ synthesis of fluorescent polydopamine on biogenic MnO2 nanoparticles as stimuli responsive multifunctional theranostics, Biomater. Sci., 2021, 9, 5897. Guang-Jing Feng, Shuang-Shuang Wang, Jian Lv, Tao Luo, Yuzhou Wu, Hai Dong*, Improved Synthesis of 1-Glycosyl Thioacetates and Its Application in the Synthesis of Thioglucoside Gliflozin Analogues, Eur. J. Org. Chem, 2021, 2940. Junying Xiao, Hui Cao, Siyu Guo, Shengze Xiao, Na Li, Min Li, Yuzhou Wu, Hongmei Liu*, Long-term administration of low-dose selenium nanoparticles with different sizes aggravated atherosclerotic lesions and exhibited toxicity in apolipoprotein E-deficient mice, Chem. Biol. Interact, 2021, 247, 109601 Meizhou Zhang, Shuangshuang Wang, Longjie Li, Mengran Li, Xinyi Cheng, Yiwei Shi, Yuzhou Wu*, Digital Numbers Constructed by Fine Patterned Polydopamine on DNA Templates, Macromol Rapid Commun, 2021, 42, e2100441. Shanshan Wu, Yi Chen, Xiaodong Guo, Yuzhou Wu*, Collagen mineralization and its applications in hard tissue repair, Mater. Chem. Front., 2021, 5, 7071-7087. Weiguo Qiao, Teng Ma, Shuangshuang Wang, Longjie Li, Miao Liu, Hao Jiang, Yuzhou Wu, Jintao Zhu, Zhong'an Li*, Adv. Funct. Mater. 2021, 31, 2105452. Tai-Ping Zhou, Fangrui Zhong,* Yuzhou Wu and Rong-Zhen Liao,* “Regioselectivity and stereoselectivity of intramolecular [2 + 2] photocycloaddition catalyzed by chiral thioxanthone: a quantum chemical study”, Org. Biomol. Chem. 2021, 19, 1532-1540 So Yeon Ahn, Jin Liu, Srivithya Vellampatti, Yuzhou Wu*, Soong Ho Um* DNA Transformations for Diagnosis and Therapy, Adv. Funct. Mater. 2021, 31, 2008279. Qianqian Liu, Yu-Jin Kim, Gwang-Bum Im, Jintao Zhu, Yuzhou Wu, Yijing Liu,* Suk Ho Bhang* Inorganic Nanoparticles Applied as Functional Therapeutics, Adv. Funct. Mater. 2021, 31, 2008171. Shanshan Wu, Meizhou Zhang , Jie Song, Stefan Weber, Xiaoguo Liu, Chunhai Fan, and Yuzhou Wu*, Fine Customization of Calcium Phosphate Nanostructures with Site-Specific Modification by DNA Templated Mineralization, ACS Nano 2021, 15, 1555. Wanying Ye, Haijie Han, Huan Li, Qiao Jin, *, Yuzhou Wu, Sabyasachi Chakrabortty, Tanja Weil, Jian Ji, Polymer coated nanodiamonds as gemcitabine prodrug with enzymatic sensitivity for pancreatic cancer treatment, Progress in Natural Science: Materials International, 2020, 30, 711. Longjie Li, ‡ Wenkai Zhang,‡ Xiaofeng Tang, Zejian Li, Yuzhou Wu,* Xianjin Xiao* Fine and bidirectional regulation of toehold-mediated DNA strand displacement by a wedge-like DNA tool, Chem. Commun., 2020, 56, 8794. Adnan Bashir, Honghua Zuo, Xunbo Lu, Yuzhou Wu, Fangrui Zhong*, Harnessing structurally unbiased ortho-benzoquinone monoimine for biomimetic oxidative [4+2] cycloaddition with enamines, Chem. Commun., 2020, 56, 5965. Ahmed El-Harairy,* Mennatallah Shaheen, Jun Li, Yuzhou Wu, Minghao Li, Yanlong Gu, Synthesis of α-indolylacrylates as potential anticancer agents using a Bronsted acid ionic liquid catalyst and the butyl acetate solvent. RSC Adv., 2020, 10, 13507. Juan Guo, Huan Guo, Jin Liu*, Fangrui Zhong and Yuzhou Wu*, Manganese(II) Oxidizing Bacteria as Whole-Cell Catalyst for beta -Keto Ester Oxidation, Int. J. Mol. Sci. 2020, 21, 1709. Yuan Zhuang, Longjie Li, Liandong Feng, Shuangshuang Wang, Huimin Su, Haijuan Liu, Hongmei Liu* and Yuzhou Wu*, Mitochondrion-targeted selenium nanoparticles enhance reactive oxygen species-mediated cell death, Nanoscale, 2020, 12, 1389. Xuemei Xu, Pia Winterwerber, David Ng, Yuzhou Wu*, DNA-Programmed Chemical Synthesis of Polymers and Inorganic Nanomaterials, Top. Curr. Chem. 2020, 378, 31. Jessica Wagner, Longjie Li, Johanna Simon, Lea Krutzke, Katharina Landfester, Volker Mail-nder, Klaus Mgllen, David Y. W. Ng,* Yuzhou Wu,* and Tanja Weil* Amphiphilic Polyphenylene Dendron Conjugates for Surface Remodeling of Adenovirus 5, Angew. Chem. Int. Ed. 2020, 59, 5712.

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