个人简介
教育背景:
1999.9-2002.7 中南大学湘雅医学院博士
1987.9-1990.7 陕西中医学院药学系硕士
1979.9-1984.7 湖南中医学院医疗系学士
工作经历:
2005.3-至今 北京化工大学生命科学与技术学院教授
2002.9-2005.2 中国中医科学院基础理论研究所博士后
1993.10-1999.8 九芝堂股份公司药物研究所所长 主任医师
1984.8-1993.9 89800部队军医
研究领域
1)中药新药开发
2) 分子诊断研究
3)环境与健康研究
近期论文
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Metabolic Profile Changes of CCl4-Liver Fibrosis and Inhibitory Effects of Jiaqi Ganxian Granule[J]. Molecules. 2016, 21(6), 698.
In-Silico Prediction of Blood-Brain Barrier Permeability, SAR and QSAR in Environmental Research, 2013, 24(1), 61-74.
Quantitative structure and bioactivity relationship study on HCV NS5B polymerase inhibitors, SAR and QSAR in Environmental Research, 2014, 25(1), 1-15.
Classification Models of HCV NS3 Protease Inhibitors Based on Support Vector Machine (SVM),Combinatorial Chemistry & High Throughput Screening, 2015, 18(1), 24-32.
QSAR Studies on the Bioactivity of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase Inhibitors, Letters in Drug Design & Discovery, 2015, 12(9), 728-735.
Classification of Mixtures of Chinese Herbal Medicines Based on a Self-Organizing Map (SOM), Molecular Informatics, 2016, 35(3-4), 109-115.
Using support vector machine (SVM) for classification of selectivity of H1N1 neuraminidase inhibitors, Molecular Informatics, 2016, 35(3-4), 116-124.
Telomerase Activity Detection with Amplification-Free Single Molecule Stochastic Binding Assay,Anal. Chem.,2017,DOI: 10.1021/acs.analchem.6b04883
Discrimination Cascade Enabled Selective Detection of Single-Nucleotide Mutation, ACS Sensors,2017,DOI: 10.1021/acssensors.7b00005
Single-Molecule Counting of Point Mutations by Transient DNA Binding,Sci. Rep.2017.7, 43824.