Oliver, Brian - University of Technology Sydney

个人简介

A/Prof Oliver is a translational researcher supported by a NHMRC Career Development Fellowship 2 (Industry) – the aim of which is to identify and develop new ways of treating respiratory diseases. My scientific training began at the National Heart and Lung Institute, UK, where I mastered the isolation and in-vitro culture of several types of human lung cells. I then had further training in both molecular biology (two publications: we discovered a new gene in humans, and examined epigenetic programming events during embryogenesis) (University of Leeds) and then virology at Prof Sebastian Johnston’s laboratory at Imperial College, UK before commencing my PhD at The University of Sydney (supervised by Prof Judith Black). I am now head of the Respiratory Molecular Pathogenesis group with laboratory facilities located at both UTS and the Woolcock Institute . The work from my group is recognised to be amongst the best in the world, evidenced by selection for presentation at symposia at both national and large international conferences as well as resulting in prestigious publications.

研究领域

A/Prof Oliver is a translational researcher supported by a NHMRC Career Development Fellowship leve 2 (Industry) – the aim of which is to identify and develop new ways of treating respiratory diseases. My research can be divided into two main areas: Respiratory infectious diseases Respiratory Pathogenesis

近期论文

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akarya, R, Adcock, I & Oliver, BG 2019, 'Epigenetic impacts of maternal tobacco and e-vapour exposure on the offspring lung', CLINICAL EPIGENETICS, vol. 11.View/Download from: UTS OPUS or Publisher's site Bradbury, P, Patel, BS, Cidem, A, Nader, CP, Oliver, BG & Ammit, AJ 2019, 'Prostaglandin E 2, but not cAMP nor β 2 -agonists, induce tristetraprolin (TTP) in human airway smooth muscle cells', Inflammation Research.View/Download from: UTS OPUS or Publisher's site Bozier, J, Rutting, S, Xenaki, D, Peters, M, Adcock, I & Oliver, BG 2019, 'Heightened response to e-cigarettes in COPD.', ERJ open research, vol. 5, no. 1.View/Download from: Publisher's site McAlinden, KD, Deshpande, DA, Ghavami, S, Xenaki, D, Sohal, SS, Oliver, BG, Haghi, M & Sharma, P 2019, 'Autophagy Activation in Asthma Airways Remodeling.', American Journal of Respiratory Cell and Molecular Biology.View/Download from: UTS OPUS or Publisher's site Wood, LG, Li, Q, Scott, HA, Rutting, S, Berthon, BS, Gibson, PG, Hansbro, PM, Williams, E, Horvat, J, Simpson, JL, Young, P, Oliver, BG & Baines, KJ 2019, 'Saturated fatty acids, obesity, and the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in asthmatic patients.', Allergy and Clinical Immunology, vol. 143, no. 1, pp. 305-315.View/Download from: UTS OPUS or Publisher's site Rutting, S, Xenaki, D, Malouf, M, Horvat, JC, Wood, LG, Hansbro, PM & Oliver, BG 2019, 'Short-chain fatty acids increase TNFα-induced inflammation in primary human lung mesenchymal cells through the activation of p38 MAPK.', American journal of physiology. Lung cellular and molecular physiology, vol. 316, no. 1, pp. L157-L174.View/Download from: UTS OPUS or Publisher's site Ng, SW, Chan, Y, Chellappan, DK, Madheswaran, T, Zeeshan, F, Chan, YL, Collet, T, Gupta, G, Oliver, BG, Wark, P, Hansbro, N, Hsu, A, Hansbro, PM, Dua, K & Panneerselvam, J 2019, 'Molecular modulators of celastrol as the keystones for its diverse pharmacological activities', BIOMEDICINE & PHARMACOTHERAPY, vol. 109, pp. 1785-1792.View/Download from: UTS OPUS or Publisher's site Rutting, S, Zakarya, R, Bozier, J, Xenaki, D, Horvat, JC, Wood, LG, Hansbro, PM & Oliver, BG 2019, 'Dietary Fatty Acids Amplify Inflammatory Responses to Infection through p38 MAPK Signaling', AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, vol. 60, no. 5, pp. 554-568.View/Download from: UTS OPUS or Publisher's site Saad, S, Al-Odat, I, Chan, YL, McGrath, KC, Pollock, CA, Oliver, BG & Chen, H 2018, 'Maternal L-carnitine supplementation improves glucose and lipid profiles in female offspring of dams exposed to cigarette smoke.', Clinical and experimental pharmacology & physiology, vol. 45, no. 7, pp. 694-703.View/Download from: UTS OPUS or Publisher's site Sukjamnong, S, Chan, YL, Zakarya, R, Nguyen, LT, Anwer, AG, Zaky, AA, Santiyanont, R, Oliver, BG, Goldys, E, Pollock, CA, Chen, H & Saad, S 2018, 'MitoQ supplementation prevent long-term impact of maternal smoking on renal development, oxidative stress and mitochondrial density in male mice offspring.', Scientific reports, vol. 8, no. 1.View/Download from: UTS OPUS or Publisher's site Mitchell, AB, Tang, B, Shojaei, M, Barnes, LS, Nalos, M, Oliver, BG & McLean, AS 2018, 'A novel sampling method to detect airborne influenza and other respiratory viruses in mechanically ventilated patients: a feasibility study.', Annals of intensive care, vol. 8, no. 45.View/Download from: UTS OPUS or Publisher's site Mitchell, AB, Mourad, B, Buddle, L, Peters, MJ, Oliver, BGG & Morgan, LC 2018, 'Viruses in bronchiectasis: a pilot study to explore the presence of community acquired respiratory viruses in stable patients and during acute exacerbations', BMC PULMONARY MEDICINE, vol. 18.View/Download from: UTS OPUS or Publisher's site Eapen, MS, Kota, A, Vindin, H, McAlinden, KD, Xenaki, D, Oliver, BG, Deshpande, DA, Sohal, SS & Sharma, P 2018, 'Apoptosis signal-regulating kinase 1 (ASK1) inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease (COPD).', Clinical Science.View/Download from: UTS OPUS or Publisher's site Li, G, Saad, S, Oliver, BG & Chen, H 2018, 'Heat or Burn? Impacts of Intrauterine Tobacco Smoke and E-Cigarette Vapor Exposure on the Offspring's Health Outcome.', Toxics, vol. 6, no. 3.View/Download from: UTS OPUS or Publisher's site Mitchell, AB, Mourad, B, Morgan, LC, Oliver, BGG & Glanville, AR 2018, 'Transplanting the pulmonary virome: Dynamics of transient populations', JOURNAL OF HEART AND LUNG TRANSPLANTATION, vol. 37, no. 9, pp. 1111-1118.View/Download from: Publisher's site Nissen, G, Hollaender, H, Tang, FSM, Wegmann, M, Lunding, L, Vock, C, Bachmann, A, Lemmel, S, Bartels, R, Oliver, BG, Burgess, JK, Becker, T, Kopp, MV & Weckmann, M 2018, 'Tumstatin fragment selectively inhibits neutrophil infiltration in experimental asthma exacerbation', CLINICAL AND EXPERIMENTAL ALLERGY, vol. 48, no. 11, pp. 1483-1493.View/Download from: UTS OPUS or Publisher's site Pech, M, Weckmann, M, Koenig, IR, Franke, A, Heinsen, F-A, Oliver, B, Ricklefs, I, Fuchs, O, Rabe, K, Hansen, G, Mutius, E & Kopp, M 2018, 'Rhinovirus infections change DNA methylation and mRNA expression in children with asthma', PLOS ONE, vol. 13, no. 11.View/Download from: UTS OPUS or Publisher's site Kota, A, Deshpande, D, Haghi, M, Oliver, B & Sharma, P 2018, 'Autophagy and airway fibrosis: Is there a link?', F1000Research, vol. 6.View/Download from: UTS OPUS or Publisher's site Chen, H, Li, G, Chan, YL, Chapman, DG, Sukjamnong, S, Nguyen, T, Annissa, T, McGrath, KC, Sharma, P & Oliver, BG 2018, 'Maternal E-Cigarette Exposure in Mice Alters DNA Methylation and Lung Cytokine Expression in Offspring.', American Journal of Respiratory Cell and Molecular Biology, vol. 58, no. 3, pp. 366-377.View/Download from: UTS OPUS or Publisher's site Burgess, JK, Ketheson, A, Faiz, A, Limbert Rempel, KA, Oliver, BG, Ward, JPT & Halayko, AJ 2018, 'Phenotype and Functional Features of Human Telomerase Reverse Transcriptase Immortalized Human Airway Smooth Muscle Cells from Asthmatic and Non-Asthmatic Donors.', Scientific Reports, vol. 8, no. 1, pp. 805-805.View/Download from: UTS OPUS or Publisher's site Copeland, E, Leonard, K, Carney, R, Kong, J, Forer, M, Naidoo, Y, Oliver, BGG, Seymour, JR, Woodcock, S, Burke, CM & Stow, NW 2018, 'Chronic Rhinosinusitis: Potential Role of Microbial Dysbiosis and Recommendations for Sampling Sites', Frontiers in Cellular and Infection Microbiology, vol. 8, pp. 1-14.View/Download from: UTS OPUS or Publisher's site Wang, J, Faiz, A, Ge, Q, Vermeulen, CJ, Van der Velden, J, Snibson, KJ, van de Velde, R, Sawant, S, Xenaki, D, Oliver, B, Timens, W, Ten Hacken, N, van den Berge, M, James, A, Elliot, JG, Dong, L, Burgess, JK & Ashton, AW 2018, 'Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling.', Journal of Cellular and Molecular Medicine, vol. 22, no. 5, pp. 2826-2837.View/Download from: UTS OPUS or Publisher's site Rutting, S, Xenaki, D, Lau, E, Horvat, J, Wood, LG, Hansbro, PM & Oliver, BG 2018, 'Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells', AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, vol. 314, no. 6, pp. L922-L935.View/Download from: UTS OPUS or Publisher's site Faiz, A, Weckmann, M, Tasena, H, Vermeulen, CJ, Van den Berge, M, Ten Hacken, NHT, Halayko, AJ, Ward, JPT, Lee, TH, Tjin, G, Black, JL, Haghi, M, Xu, C-J, King, GG, Farah, CS, Oliver, BG, Heijink, IH & Burgess, JK 2018, 'Profiling of healthy and asthmatic airway smooth muscle cells following interleukin-1β treatment: a novel role for CCL20 in chronic mucus hypersecretion.', European Respiratory Journal, vol. 52, no. 2, pp. 1-12.View/Download from: UTS OPUS or Publisher's site Chen, H, Li, G, Chan, YL, Nguyen, T, van Reyk, D, Saad, S & Oliver, BG 2018, 'Modulation of neural regulators of energy homeostasis, and of inflammation, in the pups of mice exposed to e-cigarettes.', Neuroscience letters, vol. 684, pp. 61-66.View/Download from: UTS OPUS or Publisher's site Fricker, M, Goggins, BJ, Mateer, S, Jones, B, Kim, RY, Gellatly, SL, Jarnicki, AG, Powell, N, Oliver, BG, Radford-Smith, G, Talley, NJ, Walker, MM, Keely, S & Hansbro, PM 2018, 'Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction.', JCI insight, vol. 3, no. 3.View/Download from: UTS OPUS or Publisher's site Chen, H, Chan, YL, Linnane, C, Mao, Y, Anwer, AG, Sapkota, A, Annissa, TF, Herok, G, Vissel, B, Oliver, BG, Saad, S & Gorrie, CA 2018, 'L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury.', Scientific reports, vol. 8, no. 1.View/Download from: UTS OPUS or Publisher's site Tonga, KO, King, GG, Farah, CS, Thamrin, C, Tang, FS, Santos, J, Sharma, P, Chapman, DG & Oliver, BG 2018, 'Steroid insensitive fixed airflow obstruction is not related to airway inflammation in older non-smokers with asthma.', Respiratory research, vol. 19, no. 1, pp. 176-176.View/Download from: UTS OPUS or Publisher's site Rutting, S, Papanicolaou, M, Xenaki, D, Wood, LG, Mullin, AM, Hansbro, PM & Oliver, BG 2018, 'Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD.', Respiratory research, vol. 19, no. 1, pp. 211-211.View/Download from: UTS OPUS or Publisher's site Ghadiri, M, Young, PM, Jarolimek, W, Grau, GER, Oliver, BGG & Traini, D 2017, 'The effect of non-specific tight junction modulators on the transepithelial transport of poorly permeable drugs across airway epithelial cells.', Journal of Drug Targeting, vol. 25, no. 4, pp. 342-349.View/Download from: UTS OPUS or Publisher's site Patel, BS, Rahman, MM, Baehring, G, Xenaki, D, Tang, FS-M, Oliver, BG & Ammit, AJ 2017, 'Roflumilast N-Oxide in Combination with Formoterol Enhances the Antiinflammatory Effect of Dexamethasone in Airway Smooth Muscle Cells.', American Journal of Respiratory Cell and Molecular Biology, vol. 56, no. 4, pp. 532-538.View/Download from: UTS OPUS or Publisher's site Chan, YL, Saad, S, Al-Odat, I, Oliver, BG, Pollock, C, Jones, NM & Chen, H 2017, 'Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers.', Frontiers in Molecular Neuroscience, vol. 10, pp. 1-15.View/Download from: UTS OPUS or Publisher's site Sharma, P, Yi, R, Nayak, A, Wang, N, Knight, MJ, Pan, S, Oliver, B & Deshpande, DA 2017, 'Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice.', Scientific Reports, vol. 7, pp. 1-14.View/Download from: UTS OPUS or Publisher's site Sukjamnong, S, Chan, YL, Zakarya, R, Saad, S, Sharma, P, Santiyanont, R, Chen, H & Oliver, BG 2017, 'Effect of long-term maternal smoking on the offspring's lung health.', American Journal of Physiology - Lung Cellular and Molecular Physiology, vol. 313, no. 2, pp. L416-L423.View/Download from: UTS OPUS or Publisher's site