Labbate, Maurizio - University of Technology Sydney

个人简介

I’m an internationally-recognised researcher in antimicrobial resistance and infectious disease. Regarding the former, I am particularly interested in movement of antimicrobial resistance genes between bacteria and their contamination in the wider environment thereby acting as a reservoir. Regarding the latter, I predominantly focus on a group of marine bacteria called Vibrio species that cause disease in humans (e.g. diarrhoeal disease such as cholera) and marine animals (e.g. aquaculture diseases). I have extensive experience and knowledge in the bacterial process of lateral gene transfer, a phenomenon that facilitates the emergence and evolution of bacterial pathogens and their resistance to antimicrobials. My work spans multiple disciplines and is focussed on the interface that microbes have with their environment and how this drives disease processes (e.g. how environmental parameters lead to disease outbreaks by Vibrio pathogens) or evolution/emergence of pathogens (e.g. selection pressure and lateral gene processes driving emergence of virulence and antimicrobial resistance). Recognising that antimicrobial resistance is an anthropogenic as well as a microbial problem, my most recent research interest, in collaboration with diverse researchers from different disciplines (e.g. medicine, pharmacy, veterinary sciences etc) is focussed on identifying the socio-cultural factors that drive stakeholder demand for antimicrobials and using this information to develop successful interventions.

研究领域

My interests are: Pathogenic Vibrio species (identification of genes involved in disease, particularly those derived by lateral gene transfer – human disease and, marine animal diseases such as oyster disease; environmental parameters leading to infectious Vibrio outbreaks) Antimicrobial resistance (resistance genes in the wider environment; socio-cultural factors driving stakeholder demand for antimicrobials) One Health (interactions between natural environmental, human and socio-economic and animal systems particularly in the fields of antimicrobial resistance and infectious disease by Vibrio species affecting humans and aquaculture) For information on Dr Maurizio Labbate's research interests - please visit his laboratory homepage (opens an external site)

近期论文

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King, WL, Jenkins, C, Go, J, Siboni, N, Seymour, JR & Labbate, M 2019, 'Characterisation of the Pacific Oyster Microbiome During a Summer Mortality Event.', Microbial Ecology.View/Download from: Publisher's site Green, TJ, Siboni, N, King, WL, Labbate, M, Seymour, JR & Raftos, D 2019, 'Simulated Marine Heat Wave Alters Abundance and Structure of Vibrio Populations Associated with the Pacific Oyster Resulting in a Mass Mortality Event.', Microbial ecology.View/Download from: UTS OPUS or Publisher's site King, WL, Jenkins, C, Seymour, JR & Labbate, M 2019, 'Oyster disease in a changing environment: Decrypting the link between pathogen, microbiome and environment.', Marine environmental research.View/Download from: UTS OPUS or Publisher's site King, WL, Siboni, N, Williams, NLR, Kahlke, T, Nguyen, KV, Jenkins, C, Dove, M, O'Connor, W, Seymour, JR & Labbate, M 2019, 'Variability in the Composition of Pacific Oyster Microbiomes Across Oyster Families Exhibiting Different Levels of Susceptibility to OsHV-1 mu var Disease', FRONTIERS IN MICROBIOLOGY, vol. 10.View/Download from: Publisher's site Zhuo, A, Labbate, M, Norris, JM, Gilbert, GL, Ward, MP, Bajorek, BV, Degeling, C, Rowbotham, SJ, Dawson, A, Ky-Anh, N, Hill-Cawthorne, GA, Sorrell, TC, Govendir, M, Kesson, AM, Iredell, JR & Dominey-Howes, D 2018, 'Opportunities and challenges to improving antibiotic prescribing practices through a One Health approach: results of a comparative survey of doctors, dentists and veterinarians in Australia', BMJ OPEN, vol. 8, no. 3.View/Download from: UTS OPUS or Publisher's site Mahbub, KR, Bahar, M, Megharaj, M & Labbate, M 2018, 'Are the existing guideline values adequate to protect soil health from inorganic mercury contamination?', Environment International, vol. 117, pp. 10-15.View/Download from: UTS OPUS or Publisher's site Mahbub, KR, Bahar, MM, Labbate, M, Krishnan, K, Andrews, S, Naidu, R & Mallavarapu, M 2017, 'Bioremediation of mercury: not properly exploited in contaminated soils!', Applied Microbiology and Biotechnology, vol. 101, no. 3, pp. 963-976.View/Download from: UTS OPUS or Publisher's site Mahbub, KR, Kader, M, Krishnan, K, Labbate, M, Naidu, R & Megharaj, M 2017, 'Toxicity of Inorganic Mercury to Native Australian Grass Grown in Three Different Soils', Bulletin of Environmental Contamination and Toxicology, vol. 98, no. 6, pp. 850-855.View/Download from: UTS OPUS or Publisher's site Donnelly, S, Huston, WM, Johnson, M, Tiberti, N, Saunders, B, O'Brien, B, Burke, C, Labbate, M & Combes, V 2017, 'Targeting the master regulator mTOR: a new approach to prevent the neurological of consequences of parasitic infections?', Parasites & Vectors, vol. 10, no. 1, pp. 1-6.View/Download from: UTS OPUS or Publisher's site Global Alliance for Infections in Surgery Working Group & Labbate, M 2017, 'A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway.', Surgical Infections, vol. 18, no. 8, pp. 846-853.View/Download from: UTS OPUS or Publisher's site Labbate, M, Seymour, JR, Lauro, F & Brown, MV 2016, 'Anthropogenic Impacts on the Microbial Ecology and Function of Aquatic Environments', FRONTIERS IN MICROBIOLOGY, vol. 7.View/Download from: UTS OPUS or Publisher's site Labbate, M, Orata, FD, Petty, NK, Jayatilleke, ND, King, WL, Kirchberger, PC, Allen, C, Mann, G, Mutreja, A, Thomson, NR, Boucher, Y & Charles, IG 2016, 'A genomic island in Vibrio cholerae with VPI-1 site-specific recombination characteristics contains CRISPR-Cas and type VI secretion modules.', Scientific Reports, vol. 6, pp. 1-7.View/Download from: UTS OPUS or Publisher's site Michael, CA, Franks, AE & Labbate, M 2016, 'The antimicrobial resistance crisis: management through gene monitoring', OPEN BIOLOGY, vol. 6, no. 11.View/Download from: UTS OPUS or Publisher's site Siboni, N, Balaraju, V, Carney, R, Labbate, M & Seymour, JR 2016, 'Spatiotemporal Dynamics of Vibrio spp. within the Sydny harbour Estuary', FRONTIERS IN MICROBIOLOGY, vol. 7.View/Download from: UTS OPUS or Publisher's site Dominey-Howes, D, Bajorek, B, Michael, CA, Betteridge, B, Iredell, J & Labbate, M 2015, 'Applying the emergency risk management process to tackle the crisis of antibiotic resistance', FRONTIERS IN MICROBIOLOGY, vol. 6.View/Download from: UTS OPUS or Publisher's site Labbate, M, Islam, A, Monahan, LG, Stokes, HW, Rapa, R, Mutreja, A, Thomson, N & Charles, IG 2015, 'A genomic island integrated into recA of Vibrio cholerae contains a divergent recA and provides multi-pathway protection from DNA damage', Environmental Microbiology.View/Download from: UTS OPUS or Publisher's site Laczka, OF, Labbate, M, Seymour, JR, Bourne, DG, Fielder, SS & Doblin, MA 2014, 'Surface Immuno-Functionalisation for the Capture and Detection of Vibrio Species in the Marine Environment: A New Management Tool for Industrial Facilities', PLOS ONE, vol. 9, no. 10.View/Download from: UTS OPUS or Publisher's site Michael, CA, Dominey-Howes, D & Labbate, M 2014, 'The antimicrobial resistance crisis: causes, consequences, and management.', Frontiers in Public Health, vol. 2, pp. 1-6.View/Download from: UTS OPUS or Publisher's site Dominey-Howes, D, Michael, C & Labbate, M 2014, 'Why emergency management should be interested in the emergence of antibiotic resistance', The Australian Journal of Emergency Management, vol. 29, no. 3, pp. 11-15.View/Download from: UTS OPUS Laczka, OF, Labbate, M & Doblin, MA 2014, 'Application of an ELISA-type amperometric assay to the detection of Vibrio species with screenprinted electrodes', Analytical Methods, vol. 6, pp. 2020-2023.View/Download from: UTS OPUS or Publisher's site