Gorrie, Cathy - University of Technology Sydney

个人简介

Cathy is a member of the Biology and Biotechnology discipline in the School of Life Sciences. Cathy's research interest in neuroscience, in particular in neurotrauma (brain and spinal cord injury). She has conducted studies on human autopsy material and uses animal models to investigate damage and repair of the central nervous system. She completed her PhD in 2006 (UNSW), and joined UTS in 2011 teaching Biomedical Science. Her fields of expertise are in Histology and Immunohoistochemistry. She has established sucessful research collaborations with academics from Australian and overseas universities and is currently investigating the role of endogenous neural progenitor cells (stem cells) in spinal cord tissue and how spinal cord injury in the young differs from adult injury.

研究领域

An examination of the cellular and inflammatory response in rats after spinal cord injury, and the effects of age, location and survival time (UTS Center for Health Technologies) Modulation of connexin43 hemichannels in reducing secondary spinal cord injuries (Spinal Cord Injury Network & New Zealand Neurological Foundation with the Catwalk Trust) Endogenous neural progenitor cell responses following spinal cord (Early Career Research Grant, UTS) Age related cytoskeletal pathology in human brain from Sri Lanka: A correlation of morphological and molecular genetic study Spinal cord loading conditions in young and adult spinal cord injuries (SpinalCare)

近期论文

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Pelegri, NG, Gorrie, CA & Santos, J 2019, 'Rat Hippocampal Neural Stem Cell Modulation Using PDGF, VEGF, PDGF/VEGF, and BDNF.', Stem Cells International, vol. 2019, p. 4978917.View/Download from: UTS OPUS or Publisher's site Tonkin, RS, Bowles, C, Perera, CJ, Keating, BA, Makker, PGS, Duffy, SS, Lees, JG, Tran, C, Don, AS, Fath, T, Liu, L, O'Carroll, SJ, Nicholson, LFB, Green, CR, Gorrie, C & Moalem-Taylor, G 2018, 'Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice.', Experimental neurology, vol. 300, pp. 1-12.View/Download from: UTS OPUS or Publisher's site Nguyen, T, Li, GE, Chen, H, Cranfield, CG, McGrath, KC & Gorrie, CA 2018, 'Maternal E-Cigarette Exposure Results in Cognitive and Epigenetic Alterations in Offspring in a Mouse Model.', Chemical research in toxicology, vol. 31, no. 7, pp. 601-611.View/Download from: UTS OPUS or Publisher's site Chen, H, Chan, YL, Linnane, C, Mao, Y, Anwer, AG, Sapkota, A, Annissa, TF, Herok, G, Vissel, B, Oliver, BG, Saad, S & Gorrie, CA 2018, 'L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury.', Scientific reports, vol. 8, no. 1.View/Download from: UTS OPUS or Publisher's site Mao, Y, Tonkin, RS, Nguyen, T, O'Carroll, SJ, Nicholson, LF, Green, CR, Moalem-Taylor, G & Gorrie, CA 2017, 'Systemic administration of Connexin43 mimetic peptide improves functional recovery following traumatic spinal cord injury in adult rats.', Journal of Neurotrauma, vol. 34, no. 3, pp. 707-719.View/Download from: UTS OPUS or Publisher's site Sutherland, TC, Mathews, KJ, Mao, Y, Nguyen, T & Gorrie, CA 2017, 'Differences in the Cellular Response to Acute Spinal Cord Injury between Developing and Mature Rats Highlights the Potential Significance of the Inflammatory Response.', Frontiers in Cellular Neuroscience, vol. 10, pp. 1-18.View/Download from: UTS OPUS or Publisher's site Mao, Y, Nguyen, T, Tonkin, RS, Lees, JG, Warren, C, O'Carroll, SJ, Nicholson, LFB, Green, CR, Moalem-Taylor, G & Gorrie, CA 2017, 'Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats.', Experimental Brain Research, vol. 235, no. 10, pp. 3033-3048.View/Download from: UTS OPUS or Publisher's site Nguyen, T, Mao, Y, Sutherland, T & Gorrie, CA 2017, 'Neural progenitor cells but not astrocytes respond distally to thoracic spinal cord injury in rat models.', Neural regeneration research, vol. 12, no. 11, pp. 1885-1894.View/Download from: UTS OPUS or Publisher's site Wijesinghe, P, Gorrie, C, Shankar, SK, Chickabasaviah, YT, Amaratunga, D, Hulathduwa, S, Kumara, KS, Samarasinghe, K, Suh, Y-H, Steinbusch, HWM & De Silva, KRD 2017, 'Early stages of Alzheimer's disease are alarming signs in injury deaths caused by traffic accidents in elderly people (≥60 years of age): A neuropathological study.', Indian Journal of Psychiatry, vol. 59, no. 4, pp. 471-477.View/Download from: UTS OPUS or Publisher's site Mao, Y, Nguyen, T, Sutherland, T & Gorrie, CA 2016, 'Endogenous neural progenitor cells in the repair of the injured spinal cord.', Neural regeneration research, vol. 11, no. 7, pp. 1075-1076.View/Download from: UTS OPUS or Publisher's site Wijesinghe, P, Shankar, SK, Yasha, TC, Gorrie, C, Amaratunga, D, Hulathduwa, S, Kumara, KS, Samarasinghe, K, Suh, YH, Steinbusch, HW & De Silva, KR 2016, 'Vascular Contributions in Alzheimer's Disease-Related Neuropathological Changes: First Autopsy Evidence from a South Asian Aging Population.', Journal of Alzheimer's Disease, vol. 54, no. 4, pp. 1607-1618.View/Download from: UTS OPUS or Publisher's site Chen, H, Chan, YL, Nguyen, LT, Mao, Y, de Rosa, A, Beh, IT, Chee, C, Oliver, B, Herok, G, Saad, S & Gorrie, C 2016, 'Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol. 43, no. 11, pp. 1107-1114.View/Download from: UTS OPUS or Publisher's site Wijesinghe, P, Shankar, SK, Chickabasaviah, YT, Gorrie, C, Amaratunga, D, Hulathduwa, S, Kumara, KS, Samarasinghe, K, Suh, YH, Steinbusch, HW & De Silva, KRD 2016, 'Cytoskeletal pathologies of age-related diseases between elderly Sri Lankan (Colombo) and Indian (Bangalore) brain samples', Current Alzheimer Research, vol. 13, no. 3, pp. 268-280.View/Download from: UTS OPUS or Publisher's site Mao, Y, Mathews, K & Gorrie, CA 2016, 'Temporal Response of Endogenous Neural Progenitor Cells Following Injury to the Adult Rat Spinal Cord', FRONTIERS IN CELLULAR NEUROSCIENCE, vol. 10.View/Download from: UTS OPUS or Publisher's site Cawsey, T, Duflou, J, Weickert, CS & Gorrie, CA 2015, 'Nestin-Positive Ependymal Cells Are Increased in the Human Spinal Cord after Traumatic Central Nervous System Injury', JOURNAL OF NEUROTRAUMA, vol. 32, no. 18, pp. 1393-1402.View/Download from: UTS OPUS or Publisher's site Tonkin, RS, Mao, Y, O'Carroll, SJ, Nicholson, LF, Green, CR, Gorrie, CA & Moalem-Taylor, G 2015, 'Gap junction proteins and their role in spinal cord injury.', Frontiers in Molecular Neuroscience, vol. 7, pp. 1-9.View/Download from: UTS OPUS or Publisher's site Chan, YL, Saad, S, Simar, D, Oliver, B, McGrath, K, Reyk, DV, Bertrand, PP, Gorrie, C, Pollock, C & Chen, H 2015, 'Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams', International Journal of Developmental Neuroscience, vol. 46, pp. 67-75.View/Download from: UTS OPUS or Publisher's site O'Carroll, SJ, Gorrie, C, Velamoor, S, Green, CR & Nicholson, LF 2013, 'Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury', Journal Of Neuroscience Research, vol. 75, no. 3, pp. 256-267.View/Download from: UTS OPUS or Publisher's site Gorrie, C, Larsen, L & Waite, PM 2013, 'Age and gender differences in perceptions of traffic risk and safety for older pedestrians in metropolitan Sydney, Australia', Journal of Australasian College of Road Safety, vol. 24, no. 4, pp. 28-36.View/Download from: UTS OPUS Lau, NS, Gorrie, C, Chia, YJ, Bilston, LE & Clarke, EC 2013, 'Severity of spinal cord injury in adult and infant rats following vertebral dislocation depends on displacement but not speed', Journal of Neurotrauma, vol. 30, no. 15, pp. 1361-1373.View/Download from: UTS OPUS or Publisher's site Wu, A, Lauschke, JL, Gorrie, C, Cameron, N, Hayward, I, Mackay-Sim, A & Waite, PM 2011, 'Delayed olfactory ensheathing cell transplants reduce nociception after dorsal root injury', Experimental Neurology, vol. 229, no. 1, pp. 143-157.View/Download from: UTS OPUS or Publisher's site Hill, F, Kim, CF, Gorrie, C & Moalem-Taylor, G 2011, 'Interleukin-17 deficiency improves locomotor recovery and tissue sparing after spinal cord contusion injury in mice', Neuroscience Letters, vol. 487, no. 3, pp. 363-367.View/Download from: UTS OPUS or Publisher's site Gorrie, C, Hayward, I, Cameron, N, Kailainathan, G, Nandapalan, N, Sutharsan, R, Wang, J, Mackay-sim, A & Waite, P 2010, 'Effects of human OEC-derived cell transplants in rodent spinal cord contusion injury', Brain Research, vol. 1337, no. 1, pp. 8-20.View/Download from: UTS OPUS or Publisher's site Gorrie, C.A., Waite, M.E. & Rogers, L.J. 2009, 'Correlations Between Hand Preference and Cortical Thickness in the Secondary Somatosensory (SII) Cortex of the Common Marmoset, Callithrix jacchus (vol 122, pg 1343, 2008)', BEHAVIORAL NEUROSCIENCE, vol. 123, no. 2, pp. 468-III. Leong, G, Gorrie, C, Ng, K, Rutkowski, S & Waite, P 2009, 'Electrical perceptual threshold testing: A validation study', Journal Of Spinal Cord Medicine, vol. 32, no. 2, pp. 140-146.View/Download from: UTS OPUS Gorrie, C, Brown, JS & Waite, P 2008, 'Crash characteristics of older pedestrian fatalities: Dementia pathology may be related to 'at risk' traffic situations', Accident Analysis and Prevention, vol. 40, no. 3, pp. 912-919.View/Download from: UTS OPUS or Publisher's site Gorrie, C, Waite, P & Rogers, L 2008, 'Correlations between hand preference and cortical thickness in the secondary somatosensory (SII) cortex of the common marmoset, Callithrix jacchus', Behavioral Neuroscience, vol. 122, no. 6, pp. 1343-1351.View/Download from: UTS OPUS or Publisher's site