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个人简介

I obtained my PhD in microbiology from the University of New South Wales in 2010. My research focused on the ecology of host associated bacterial communities from the marine environment, and I now employ the same techniques to study microbial communities associated with the human body (the human microbiota). I use observational techniques to examine differences in various states of health and disease, to infer possible relationships between our reisdent bacteria and health.

研究领域

I am interested in understanding the ecology of microbial communities, and how those communities interact with living hosts. In the case of microbial communities that live on humans (the human microbiome), these microbes are thought to play important roles in our immune development, and to protect us from pathogenic microbes. Many diseases have been linked to shifts in our microbial communities, and these shifts are implicated in disease development. My ultimate aim is to understand how our native microbial communities interact with us to keep us healthy, and how these communities can be manipulated in the case of disease to achieve better health outcomes.

近期论文

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Chahwan, B, Kwan, S, Isik, A, van Hemert, S, Burke, C & Roberts, L 2019, 'Gut feelings: A randomised, triple-blind, placebo-controlled trial of probiotics for depressive symptoms', Journal of Affective Disorders, vol. 253, pp. 317-326.View/Download from: Publisher's site Copeland, E, Leonard, K, Carney, R, Kong, J, Forer, M, Naidoo, Y, Oliver, BGG, Seymour, JR, Woodcock, S, Burke, CM & Stow, NW 2018, 'Chronic Rhinosinusitis: Potential Role of Microbial Dysbiosis and Recommendations for Sampling Sites', Frontiers in Cellular and Infection Microbiology, vol. 8, pp. 1-14.View/Download from: UTS OPUS or Publisher's site Burke, C, Burnard, D, Polkinghorne, A, Webb, J & Huston, WM 2018, 'Cloacal and Ocular Microbiota of the Endangered Australian Northern Quoll.', Microorganisms, vol. 6, no. 3.View/Download from: UTS OPUS or Publisher's site Mediati, DG, Burke, CM, Ansari, S, Harry, EJ & Duggin, IG 2018, 'High-throughput sequencing of sorted expression libraries reveals inhibitors of bacterial cell division.', BMC genomics, vol. 19, no. 1.View/Download from: UTS OPUS or Publisher's site Deutscher, AT, Burke, CM, Darling, AE, Riegler, M, Reynolds, OL & Chapman, TA 2018, 'Near full-length 16S rRNA gene next-generation sequencing revealed Asaia as a common midgut bacterium of wild and domesticated Queensland fruit fly larvae.', Microbiome, vol. 6, no. 1.View/Download from: UTS OPUS or Publisher's site Donnelly, S, Huston, WM, Johnson, M, Tiberti, N, Saunders, B, O'Brien, B, Burke, C, Labbate, M & Combes, V 2017, 'Targeting the master regulator mTOR: a new approach to prevent the neurological of consequences of parasitic infections?', Parasites & Vectors, vol. 10, no. 1, pp. 1-6.View/Download from: UTS OPUS or Publisher's site Darling, AE, Liu, M, Worden, P, Monahan, L, Demaere, M, Burke, C, Djordjevic, S & Charles, I 2017, 'Evaluation of ddRADseq for reduced representation metagenome sequencing', PeerJ, vol. 5.View/Download from: UTS OPUS or Publisher's site Gardiner, M, Vicaretti, M, Sparks, J, Bansal, S, Bush, S, Liu, M, Darling, A, Harry, E & Burke, CM 2017, 'A longitudinal study of the diabetic skin and wound microbiome.', PeerJ, vol. 5, pp. e3543-e3543.View/Download from: UTS OPUS or Publisher's site Burke, CM & Darling, AE 2016, 'A method for high precision sequencing of near full-length 16S rRNA genes on an Illumina MiSeq', PEERJ, vol. 4.View/Download from: UTS OPUS or Publisher's site Joss, TV, Burke, CM, Hudson, BJ, Darling, AE, Forer, M, Alber, DG, Charles, IG & Stow, NW 2016, 'Bacterial Communities Vary between Sinuses in Chronic Rhinosinusitis Patients.', Frontiers in Microbiology, vol. 6, pp. 1-11.View/Download from: UTS OPUS or Publisher's site Lu, J, Turnbull, L, Burke, CM, Liu, MY, Carter, DA, Schlothauer, RC, Whitchurch, CB & Harry, L 2014, 'Manuka-type honeys can eradicate biofilms produced by Staphylococcus aureus strains with different biofilm-forming abilities', PeerJ, vol. 2.View/Download from: UTS OPUS or Publisher's site Egan, S, Harder, T, Burke, CM, Steinberg, P, Kjelleberg, SL & Thomas, T 2013, 'The Seaweed Holobiont: Understanding Seaweed-bacteria Interactions', FEMS Microbiology Reviews, vol. 37, no. 3, pp. 462-476.View/Download from: UTS OPUS or Publisher's site Burke, CM, Liu, MY, Britton, WJ, Triccas, JA, Thomas, T, Smith, A, Allen, S, Salomon, R & Harry, L 2013, 'Harnessing Single Cell Sorting To Identify Cell Division Genes And Regulators In Bacteria', Plos One, vol. 8, no. 4, pp. 1-13.View/Download from: UTS OPUS or Publisher's site Burke, CM, Steinberg, P, Rusch, DB, Kjelleberg, SL & Thomas, T 2011, 'Bacterial community assembly based on functional genes rather than species', Proceedings of The National Academy of Sciences of the United States of America, vol. 108, no. 34, pp. 14288-14293.View/Download from: UTS OPUS or Publisher's site Yung, P, Burke, CM, Kjelleberg, SL, Thomas, T & Lewis, M 2011, 'Novel Antibacterial Proteins From The Microbial Communities Associated With The Sponge Cymbastela Concentrica And The Green Alga Ulva Australis', Applied and Environmental Microbiology, vol. 77, no. 4, pp. 1512-1515.View/Download from: UTS OPUS or Publisher's site Burke, CM, Thomas, T, Lewis, M, Steinberg, P & Kjelleberg, S 2011, 'Composition, uniqueness and variability of the epiphytic bacterial community of the green alga Ulva australis', ISME Journal, vol. 5, no. 4, pp. 590-600.View/Download from: UTS OPUS or Publisher's site Ballestriero, F, Thomas, T, Burke, C, Egan, S & Kjelleberg, S 2010, 'Identification of Compounds with Bioactivity against the Nematode Caenorhabditis elegans by a Screen Based on the Functional Genomics of the Marine Bacterium Pseudoalteromonas tunicata D2', APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 76, no. 17, pp. 5710-5717.View/Download from: UTS OPUS or Publisher's site Tujula, NA, Crocetti, GR, Burke, C, Thomas, T, Holmstrom, C & Kjelleberg, S 2010, 'Variability and abundance of the epiphytic bacterial community associated with a green marine Ulvacean alga', ISME JOURNAL, vol. 4, no. 2, pp. 301-311.View/Download from: Publisher's site Yung, PY, Burke, C, Lewis, M, Egan, S, Kjelleberg, S & Thomas, T 2009, 'Phylogenetic screening of a bacterial, metagenomic library using homing endonuclease restriction and marker insertion', NUCLEIC ACIDS RESEARCH, vol. 37, no. 21.View/Download from: UTS OPUS or Publisher's site Burke, C, Kjelleberg, S & Thomas, T 2009, 'Selective Extraction of Bacterial DNA from the Surfaces of Macroalgae', APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 75, no. 1, pp. 252-256.View/Download from: UTS OPUS or Publisher's site Thomas, T, Evans, FF, Schleheck, D, Mai-Prochnow, A, Burke, C, Penesyan, A, Dalisay, DS, Stelzer-Braid, S, Saunders, N, Johnson, J, Ferriera, S, Kjelleberg, S & Egan, S 2008, 'Analysis of the Pseudoalteromonas tunicata Genome Reveals Properties of a Surface-Associated Life Style in the Marine Environment', PLOS ONE, vol. 3, no. 9.View/Download from: UTS OPUS or Publisher's site Burke, C, Thomas, T, Egan, S & Kjelleberg, S 2007, 'The use of functional genomics for the identification of a gene cluster encoding for the biosynthesis of an antifungal tambjamine in the marine bacterium Pseudoalteromonas tunicata', ENVIRONMENTAL MICROBIOLOGY, vol. 9, no. 3, pp. 814-818.View/Download from: Publisher's site

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