Morgan, Joshua T - University of California, Riverside

个人简介

Research in my lab lies at the interface of tissue-scale biology and aging. In aging, the tissues of our bodies begin to degrade, losing function and resilience. While even healthy tissue suffers some loss-of-function with age, pathological declines in tissue function, resulting in severe impairment of quality of life or even death, are increasingly common in our aging population. Using a combination of molecular, genetic and tissue engineering approaches, my lab generates tissue-scale models of aging tissue. By investigating aging processes at the tissue-scale, we gain insight into how aging-associated changes in the tissue microenvironment propagate upwards in scale to loss of function in the tissue or organ. In the long term, by collaborating with clinical researchers at Riverside and other institutions, our research will guide the development of novel therapeutics to ameliorate degeneration associated with aging and increase the quality of life of geriatric patients.

研究领域

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Aging-Associated DiseaseTissue EngineeringCell and Tissue Mechanotransduction