Sternberg, Paul W - California Institute of Technology, Caltech - Division of Biology and Biological Engineering

个人简介

B.A., Hampshire College, 1978; Ph.D., Massachusetts Institute of Technology, 1984. Assistant Professor, Caltech, 1987-92; Associate Professor, 1992-96; Professor, 1996-2004; Morgan Professor, 2004-17; Bren Professor, 2017-; HHMI Investigator, 1992-2017.

研究领域

Biological Engineering; Developmental Biology and Genetics; Microbiology and Immunology; Neuroscience; Systems Biology; Evolutionary and Organismal Biology

近期论文

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Yu, H., Aleman-Meza, B., Gharib, S., Labocha, M.K., Cronin, C.J., Sternberg, P.W., Zhong, W. Systematic profiling of Caenorhabditis elegans locomotive behaviors reveals additional components in G-protein Gαq signaling. Proc Natl Acad Sci U S A. 110(29):11940-11945 PMID: 23818641. Schwarz, E. M., Kato, M. and Sternberg, P. W. (2012). Functional transcriptomics of a migrating cell in Caenorhabditis elegans. Proc Natl. Acad. USA, (40):16246-51. doi: 10.1073/pnas.1203045109. Schaedel, O. N., Gerisch, B., Antebi, A., and Sternberg, P.W. (2012). Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood. PLoS Biol. 2012 Apr;10(4):e1001306. Epub 2012 Apr 10. PMID: 22505848 Zhong, W. and Sternberg, P.W. (2006). Genome-wide prediction of C. elegans genetic interactions. Science 311: 1481-1484. Rakowski, F., Srinivasan, J., Sternberg, P. W., Karbowski, J. (2013). Synaptic polarity of the interneuron circuit controlling C. elegans locomotion. Front. Neurosci. 7:128. PMID:24106473 Dillman A.R., Guillermin M.L., Lee J.H., Kim B., Sternberg P.W., Hallem E.A.. (2012). Olfaction shapes host-parasite interactions in parasitic nematodes. Proc Natl Acad Sci U S A. 2012 Jul 31. [Epub ahead of print] PubMed PMID: 22851767. Narayan, A., Laurent, G., and Sternberg, P.W. (2011). Transfer characteristics of a thermosensory synapse in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 108:9667-72. PMID: 21606366; PMCID: PMC3111291. Hallem, E.A., Dillman, A. R., Hong, A. V., Zhang, Y., Yano, J. M., DeMarco, S. F., and Sternberg, P. W. (2011). A sensory code for host seeking in parasitic nematodes. Current Biology 21(5):377-83. PMID: 21353558. Hallem, E. A., Spencer, W. C., McWhirter, R. D., Zeller, G. Henz, S. R., Rätsch, G. Miller, D. M. III, Horvitz, H. R., Sternberg, P. W., and Ringstad, N. (2010). A receptor-type guanylate cyclase is required for carbon dioxide sensation by C. elegans. Proc Natl Acad Sci U S A. 108(1):254-9. PMID: 2117323. PMCID: PMC3017194 Whittaker, A. J. and Sternberg, P. W. (2009). Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior. BMC-Biology, Jun 22;7:33. Van Buskirk, C. and Sternberg, P. W. (2007). EGF signaling induces behavioral quiescence in C. elegans. Nature Neuroscience 10: 1300-1307. Liu, K. and Sternberg, P. W. (1995). Sensory regulation of male mating behavior in Caenorhabditis elegans. Neuron 14: 79-89. Hsueh, Y.-P., Mahanti, P., Schroeder, F. C., and Sternberg, P.W. (2013). Nematode-trapping fungi eavesdrop on nematode pheromones. Curr Biol. 2013 Jan 7;23(1):83-6. doi: 10.1016/j.cub.2012.11.035. Epub 2012 Dec 13. PubMed PMID: 23246407. Choe, A., von Reuss, S.H., Kogan, D., Gasser, R. B., Platzer, E. G., Schroeder, F. C., and Sternberg, P.W. (2012). Ascaroside signaling is widely conserved among nematodes. Curr Biol. 2012 May 8;22(9):772-80. Epub 2012 Apr 12.PMID:22503501 Izrayelit, Y., Srinivasan, J., Sternberg, P.W., and Schroeder, F. (2012). Targeted metabolomics reveals a male pheromone and sex-specific ascaroside biosynthesis in C. elegans. ACS Chem Biol. 2012 Jun 12. [Epub ahead of print] PubMed PMID: 22662967. Srinivasan, J., von Reuss, S.H., Bose, N., Zaslaver, A., Mahanti, P., Ho, M.C., O'Doherty, O. Edison, A. S. Sternberg, P.W. and Schroeder, F. C. (2012). A modular library of chemical signals regulates social behaviors in Caenorhabditis elegans. PLoS-Biology 10(1):e1001237. PMID: 22253572. von Reuss, S., Bose, Neelanjan; Srinivasan, J.; Yim, J.; Sternberg, P.; Schroeder, F. (2012). Comparative metabolomics reveals biogenesis of C. elegans ascarosides, a modular library of small molecule signals. J. Am. Chem. Soc. http://pubs.acs.org/doi/pdf/10.1021/ja210202y Srinivasan, J., Kaplan, F., Ajredini, R., Zachariah, C., Alborn, H., Teal, P., Malik, R. U., Edison, A. E., Sternberg, P. W., and Schroeder, F. C. (2008). A blend of small molecules regulates both mating and development in Caenorhabditis elegans. Nature 454: 1115-1118. Artyukhin, A. B., Yim, J. J., Srinivasan, J., Izrayelit, Y., Bose, N., von Reuss, S. H., Jo, Y., Jordan, J. M., Baugh, L. R., Cheong, M., Sternberg, P. W., Avery, L., and Schroeder, F. C. (2013). Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in C. elegans. J Biol Chem. 2013 Jun 28;288(26):18778-83. doi: 10.1074/jbc.C113.477000. PMID: 23689506.