Lois, Carlos - California Institute of Technology, Caltech - Division of Biology and Biological Engineering

个人简介

M.D., University of Valencia, 1991; Ph.D., Rockefeller University, 1995. Caltech, Visiting Associate, 2014-15; Research Professor 2015-.

研究领域

Biochemistry, Structural, and Molecular Cell Biology; Biological Engineering; Developmental Biology and Genetics; Neuroscience; Evolutionary and Organismal Biology

近期论文

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Tracing neuronal circuits in transgenic animals by transneuronal control of transcription (TRACT). Huang TH, Niesman P, Arasu D, Lee D, De La Cruz AL, Callejas A,Hong EJ, Lois C. Elife. 2017 Dec 12;6. pii: e32027. doi: 10.7554/eLife.32027. Methods to investigate the structure and connectivity of the nervous system. Lee D, Huang TH, De La Cruz A, Callejas A, Lois C. Fly (Austin). 2017 Jul 3;11(3):224-238. Liberti WA 3rd, Markowitz JE, Perkins LN, Liberti DC, Leman DP, Guitchounts G, Velho T, Kotton DN, Lois C, Gardner TJ. Unstable neurons underlie a stable learned behavior. Nat Neurosci. 2016 Dec;19(12):1665-1671. doi: 10.1038/nn.4405. View in: PubMed Huang TH, Velho T, Lois C.Monitoring cell-cell contacts in vivo in transgenic animals. Development. 2016 Nov 1;143(21):4073-4084. View in: PubMed Ravi N, Sanchez-Guardado L, Lois C, Kelsch W. Determination of the connectivity of newborn neurons in mammalian olfactory circuits. Cell Mol Life Sci. 2016 Sep 30, View in: PubMed Shima Y, Sugino K, Hempel CM, Shima M, Taneja P, Bullis JB, Mehta S, Lois C, Nelson SB. A Mammalian enhancer trap resource for discovering and manipulating neuronal cell types. Elife. 2016 Mar 21;5. pii: e13503. View in: PubMed Wu X, Zhang Y, Takle K, Bilsel O, Li Z, Lee H, Zhang Z, Li D, Fan W, Duan C, Chan EM, Lois C, Xiang Y, Han G. Dye-Sensitized Core/Active Shell Upconversion Nanoparticles for Optogenetics and Bioimaging Applications. ACS Nano. 2016 Jan 26;10(1):1060-6. View in: PubMed Bosch C, Martínez A, Masachs N, Teixeira CM, Fernaud I, Ulloa F, Pérez-Martínez E, Lois C, Comella JX, DeFelipe J, Merchán-Pérez A, Soriano E. FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons. Front Neuroanat. 2015 May 21;9:60. View in: PubMed Markowitz JE, Liberti WA 3rd, Guitchounts G, Velho T, Lois C, Gardner TJ. Mesoscopic patterns of neural activity support songbird cortical sequences. PLoS Biol. 2015 Jun 3;13(6):e1002158. View in: PubMed Velho TA, Lois C. Generation of transgenic zebra finches with replication-deficient lentiviruses. Cold Spring Harb Protoc. 2014(12):1284-9 View in: PubMed Lois C, Kelsch W. Adult neurogenesis and its promise as a hope for brain repair. Front Neurosci. 2014; 8:165. View in: PubMed Sim S, Antolin S, Lin CW, Lin Y, Lin YX, Lois C. Increased cell-intrinsic excitability induces synaptic changes in new neurons in the adult dentate gyrus that require Npas4. J Neurosci. 2013 May 1; 33(18):7928-40. View in: PubMed Ohtsuki G, Nishiyama M, Yoshida T, Murakami T, Histed M, Lois C, Ohki K. Similarity of visual selectivity among clonally related neurons in visual cortex. Neuron. 2012 Jul 12; 75(1):65-72. View in: PubMed Kelsch W, Stolfi A, Lois C. Genetic labeling of neuronal subsets through enhancer trapping in mice. PLoS One. 2012; 7(6):e38593. View in: PubMed Kelsch W, Sim S, Lois C. Increasing heterogeneity in the organization of synaptic inputs of mature olfactory bulb neurons generated in newborn rats. J Comp Neurol. 2012 Apr 15; 520(6):1327-38. View in: PubMed Magavi S, Friedmann D, Banks G, Stolfi A, Lois C. Coincident generation of pyramidal neurons and protoplasmic astrocytes in neocortical columns. J Neurosci. 2012 Apr 4; 32(14):4762-72. View in: PubMed Scott BB, Gardner T, Ji N, Fee MS, Lois C. Wandering neuronal migration in the postnatal vertebrate forebrain. J Neurosci. 2012 Jan 25; 32(4):1436-46. View in: PubMed Lois C, Groves JO. Genetics in non-genetic model systems. Curr Opin Neurobiol. 2012 Feb; 22(1):79-85. View in: PubMed Lin CW, Sim S, Ainsworth A, Okada M, Kelsch W, Lois C. Genetically increased cell-intrinsic excitability enhances neuronal integration into adult brain circuits. Neuron. 2010 Jan 14; 65(1):32-9. View in: PubMed Scott BB, Velho TA, Sim S, Lois C. Applications of avian transgenesis. ILAR J. 2010; 51(4):353-61. View in: PubMed Kelsch W, Sim S, Lois C. Watching synaptogenesis in the adult brain. Annu Rev Neurosci. 2010; 33:131-49. View in: PubMed Agate RJ, Scott BB, Haripal B, Lois C, Nottebohm F. Transgenic songbirds offer an opportunity to develop a genetic model for vocal learning. Proc Natl Acad Sci U S A. 2009 Oct 20; 106(42):17963-7. View in: PubMed Kelsch W, Lin CW, Mosley CP, Lois C. A critical period for activity-dependent synaptic development during olfactory bulb adult neurogenesis. J Neurosci. 2009 Sep 23; 29(38):11852-8. View in: PubMed Magavi SS, Lois C. Transplanted neurons form both normal and ectopic projections in the adult brain. Dev Neurobiol. 2008 Dec; 68(14):1527-37. View in: PubMed