个人简介
学习和工作经历: 2004/09 – 2008/07,中山大学生命科学学院,生物技术,学士; 2008/09 – 2013/07,中山大学中山医学院,生物化学与分子生物学,博士; 2013/12 – 2015/12,中山大学肿瘤防治中心,博士后;(获中山大学优秀博士后奖励,入选2016年全国200名优秀博士后选介) 2016/01 – 至今, 中山大学肿瘤防治中心,副研究员
研究领域
1. 肿瘤定植(colonization)机制 2. 转移器官定向选择(organotropism)机制 3. 肿瘤转移标记物筛选
近期论文
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1.Lin C#, Liu A#, Zhu J, Zhang X, Wu G, Ren P, Wu J, Li M, Li J, Song L.miR-508 sustains phosphoinositide signalling and promotes aggressive phenotype of oesophageal squamous cell carcinoma. Nat Commun. 2014 Aug 6;5:4620. 2.Liu L#, Lin C#, Liang W#, Wu S, Liu A, Wu J, Zhang X, Ren P, Li M, Song L. TBL1XR1 promotes lymphangiogenesis and lymphatic metastasis in esophageal squamous cell carcinoma. Gut. 2015 Jan; 64(1):26-36. 3.Song L#, Lin C#, Gong H, Wang C, Liu L, Wu J, Tao S, Hu B, Cheng S, Li M, Li J. miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops. Cell Research. 2013 Feb; 23(2):274-89. 4.Jiang L#, Lin C#, Song L#, Wu J, Chen B, Ying Z, Fang L, Yan X, He M, Li J, Li M.MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop. J Clin Invest. 2012 Jan;122(1):33-47. 5.Liu J, Ye L, Li Q, Wu X, Wang B, Ouyang Y, Yuan Z, Li J, Lin C*. Synaptopodin-2 suppresses metastasis of triple-negative breast cancer via inhibition of YAP/TAZ activity. J Pathol. 2017 Oct 9. doi: 10.1002/path.4995. 6.Lin C#, Liao W, Jian Y, Peng Y, Zhang X, Ye L, Cui Y, Wang B, Wu X, Xiong Z, Wu S, Li J, Wang X, Song L. CGI-99 promotes breast cancer metastasis via autocrine interleukin-6 signaling. Oncogene. 2017 Jun 29;36(26):3695-3705. 7.Lin C#, Song L#, Gong H, Liu A, Lin X, Wu J, Li M, Li J. Nkx2-8 Downregulation Promotes Angiogenesis and Activates NF-κB in Esophageal Cancer. Cancer Res. 2013 Jun 15; 73(12):3638-48. 8.Lin C#, Wu Z, Lin X, Yu C, Shi T, Zeng Y, Wang X, Li J, Song L. Knockdown of FLOT1 Impairs Cell Proliferation and Tumorigenicity in Breast Cancer through Upregulation of FOXO3a. Clin Cancer Res. 2011 May 15;17(10):3089-99. 9.Lin C#, Song L#, Liu A#, Gong H, Lin X, Wu J, Li M, Li J.Overexpression of AKIP1 Promotes Angiogenesis and Lymphangiogenesis in Human Esophageal Squamous Cell Carcinoma. Oncogene. 2015 Jan 15;34(3):384-93. 10.Gong H#, Song L#, Lin C#, Liu A, Lin X, Wu J, Li M, Li J. Downregulation of miR-138 Sustains NF-κB Activation and Promotes Lipid Raft Formation in Esophageal Squamous Cell Carcinoma. Clin Cancer Res. 2013 Mar 1; 19(5):1083-93.