陈卓佳 - 中山大学 - 肿瘤防治中心

个人简介

主要学历： 2008年本科毕业于中山大学药学院药学专业，获理学学士学位 2013年博士毕业于中山大学药学院药理学专业，获药理学博士学位工作经历： 2013年8月就职于中山大学附属肿瘤医院药学部至今 2014年到南方医科大学南方医院进行心血管专业临床药师培训一年 2017年赴美国芝加哥大学化学系进修半年副主任药师，主要研究方向为肿瘤精准治疗策略。2008年本科毕业于中山大学药学院药学专业，获理学学士学位；2013年博士毕业于中山大学药学院药理学专业，获药理学博士学位。2013年8月就职于中山大学附属肿瘤医院药学部至今，2014年~2015年于南方医科大学南方医院进行心血管专业临床药师专业培训，2017年赴美国芝加哥大学化学系进修半年

研究领域

肿瘤精准治疗策略。

近期论文

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1.Chen ZJ, Yang XL, Liu HY, Wei W, Zhang KS, Huang HB, Giesy JP, Liu HL, Du J, Wang HS. Bisphenol A modulates colorectal cancer protein profile and promotes the metastasis via induction of epithelial to mesenchymal transitions. Archives of Toxicology (2015) 89:1371-1381. (IF: 6.637) 2.Chen ZJ, Liu HY, Cheng Z, Man YB, Zhang KS, Wei W, Du J, Wong MH, Wang HS. Polybrominated diphenyl ethers (PBDEs) in human samples of mother-newborn pairs in South China and their placental transfer characteristics. Environment International (2014) 73:77-84. (IF: 5.929) 3.Chen ZJ, Wei W, Jiang GM, Liu HY, Wei WD, Yang X, Wu YM, Wong CK, Du J, Wang HS. Activation of GPER suppresses epithelial mesenchymal transition of triple negative breast cancer cells via NF-kappaB signals. Molecular Oncology (2016) 10(6):775-788. (IF: 5.367) 4.Chen ZJ, Liu HY, Ho KL, Huang HB, Liu Q, Man YB, Lam HW, Du J, Wong MH, Wang HS. Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) in paired maternal and neonatal samples from South China: placental transfer and potential risks. Environmental Research (2016) 148:72–78. (IF: 3.088) 5.Chen ZJ, Wang XD, Wang HS, Chen SD, Zhou LM, Li JL, Shu WY, Zhou JQ, Fang ZY, Zhang Y, Huang M. Simultaneous determination of valproic acid and 2-propyl-4-pentenoic acid for the prediction of clinical adverse effects in Chinese patients with epilepsy. Seizure (2012) 21:110–117. (IF: 1.798) 6.Wang ZT, Chen ZJ*, Jiang GM, Wu YM, Liu T, Yi YM, Zeng J, Du J, Wang HS. Histone deacetylase inhibitors suppress mutant p53 transcription via HDAC8/YY1 signals in triple negative breast cancer cells. Cellular Signalling (2016) 28(5):506-515. (IF: 4.191) 7.Wu YM#, Chen ZJ#, Liu H, Wei WD, Lu LL, Yang XL, Liang WT, Liu T, Liu HL, Du J, Wang HS. Inhibition of ERRalpha suppresses epithelial mesenchymal transition of triple negative breast cancer cells by directly targeting fibronectin. Oncotarget (2015) 6(28):25588-25601. (IF: 6.627) 8.Wei W#, Chen ZJ#, Zhang KS, Yang XL, Wu YM, Chen XH, Huang HB, Liu HL, Cai SH, Du J, Wang HS. The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivo. Cell Death and Disease (2014) 5:e1428. (IF: 6.044) 9.Ge LC#, Chen ZJ#, Liu H, Zhang KS, Su Q, Ma XY, Huang HB, Zhao ZD, Wang YY, Giesy JP, Du J, Wang HS. Signaling related with biphasic effects of bisphenol A (BPA) on Sertoli cell proliferation: a comparative proteomic analysis. Biochimica Biophysica Acta (2014) 1840:2663-2673. (IF: 5.083) 10.Wu YM#, Chen ZJ#, Jiang GM, Zhang KS, Qiao L, Liang SW, Zhou Y, Huang HB, Du J, Wang HS. Inverse agonist of estrogen-related receptor alpha suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathways. Oncotarget (2016) 7(11):12568-12581. (IF: 5.008) 11.Wang HS#, Chen ZJ#, Zhang G, Ou XL, Yang XL, Wong CK, Giesy JP, Du J, Chen SY. A novel micro-linear vector for in vitro and in vivo gene delivery and its application for EBV positive tumors. Plos One (2012) 7:e47159. (IF: 4.092) 12.Ge LC#, Chen ZJ#, Liu HY, Zhang KS, Liu H, Huang HB, Zhang G, Wong CK, Giesy JP, Du J, Wang HS*. Involvement of activating ERK1/2 through G protein coupled receptor 30 and estrogen receptor alpha/beta in low doses of bisphenol A promoting growth of Sertoli TM4 cells. Toxicol Letters (2014) 226:81-89. (IF: 3.522)