蔡于琛 - 中山大学 - 肿瘤防治中心

个人简介

1977年12月生，1999年本科毕业于中山大学，2009年在中山大学肿瘤防治中心获得医学博士学位。2012年至2014年在香港大学李嘉诚医学院进修。现在中山大学肿瘤防治中心华南肿瘤学国家重点实验室工作。

研究领域

微管靶向剂对缺氧诱导因子的抑制作用；靶向药物诱导自噬对肿瘤细胞的生长调节作用

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

　1.Yang H, Xia Q, Zou Y, Wang KF, Jiang WQ, Cai YC*. M410, a combretastatin A4 analogue, disrupts microtubules and inhibits HIF-1α in human breast cancer cells. Oncol Rep. 2015 Jul; 34(1): 334-340. 　2.Cai YC, Zou Y, Ye YL, Sun HY, Su QG, Wang ZX, Zeng ZL, Xian LJ. Anti-tumor activity and mechanisms of a novel vascular disrupting agent, (Z)-3,4'',5-trimethoxylstilbene-3''-O-phosphate disodium(M410). Invest New Drugs. 2011 Apr; 29(2): 300-311. 　3.Xia Q#, Cai YC#, Peng R,Wu G, Shi Y, Jiang W. The CDK1 inhibitor RO3306 improves the response of BRCA-pro?cient breast cancer cells to PARP inhibition. Int J Oncol. 2014 Mar; 44(3): 735-744. 　4.Cai YC, Wang ZH, Sun TM, Shi YX, Guo GF, Sun YL, Wu MW, Huang PY, Li S, Jiang WQ. Diarylquinoline compounds induced autophagy-associated cell death though inhibiting Akt pathway and increasing reactive oxygen species in human nasopharyngeal carcinoma cells. Oncol Rep. 2013 Mar; 29(3): 983-992. 　5.Cai YC, Xia Q, Su QG, Luo RZ, Sun YL, Shi YX, Jiang WQ. mTOR inhibitor RAD001 (everolimus) induces apoptotic, not autophagic cell death in human nasopharyngeal carcinoma cells. Int J Mol Med. 2013 Apr; 31(4): 904-912. 　6.Cai YC, Xia Q, Huang PY, Sun YL, Shi YX, Jiang WQ. Berberine inhibits the growth of Human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan; 68(1): 53-62.