李晓星 - 中山大学 - 肿瘤防治中心

个人简介

2014/02–至今副研究员，中山大学肿瘤防治中心，实验研究部　2011/01–2014/01 博士后，香港中文大学，消化疾病研究所　2010/06–2010/12 研究助理，香港中文大学，内科与药物治疗学系　2007/01–2010/05 公共卫生哲学博士，香港中文大学医学院　2003/09–2006/07 细胞生物学理学硕士，厦门大学生命科学学院　1999/09–2003/07 生命科学理学学士，厦门大学生命科学学院

研究领域

主要为研究表观遗传学调控对消化道肿瘤的影响，以及相关分子标志物的研发

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.Zhang H#, Li XX#, Yang Y, Zhang YJ, Wang HY, Zheng XFS. Significance and Mechanism of Androgen Receptor (AR) Overexpression and AR-mTOR Crosstalk in Hepatocellular Carcinoma. Hepatology. 2017. Published online 2.Jiang C#, Xu R#, Li XX#, Wang YY, Liang WQ, Zeng JD, Zhang SS, Xu XY, Yang Y, Zhang MY, Wang HY, Zheng XFS. p53R2 overexpression in cervical cancer promotes AKT signaling and EMT, and is correlated with tumor progression, metastasis and poor prognosis. Cell cycle. 2017 ; 16(18): 1673-1682. 3.Wang R#, Yin C#, Li XX#, Yang XZ, Yang Y, Zhang MY, Wang HY, Zheng XF, Reduced SOD2 expression is associated with mortality of hepatocellular carcinoma patients in a mutant p53-dependent manner. Aging. 2016; 8(6):1184-1200. 4.Li XX#, Liang Q, Liu W, Zhang N, Xu L, Zhang X, Zhang J, Sung JJ and Yu J, Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway. Oncogene. 2016; 35(19):2453-2464. 5.Xu BH#, Li XX#, Yang Y, Zhang MY, Rao HL, WangHY, and Zheng XF, Aberrant Amino Acid Signaling Promotes Growth and Metastasis of Hepatocellular Carcinomas through Rab1A-dependent Activation of mTORC1 by Rab1A, Oncotarget. 2015; 6(25):20813-20828. 6.Xu LX#, Li XX#, Chu ESH, Zhao GJ, Go MYY, Tao Q, Jin HC, Zeng ZR, Sung JJY, and Yu J, Epigenetic inactivation of BCL6B, a novel functional tumor suppressor for gastric cancer, is associated with poor survival of gastric cancer. Gut. 2012; 61:977-985. 7.Li XX#, Cheung KF, Zhao JH, Ma XW, Go MYY, Chu ESH, Shen B, Cheng ASL, Tao Q, Sung JJY, Kung HF, and Yu J, Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients. Oncogene. 2012; 31(29):3419-3430. 8.Zhao GJ, Xu LX, Chu ESH, Zhang N, Shen JY, Damirin A, Li XX*. Establishment of an orthotopic transplantation tumor model of hepatocellular carcinomas in mice. World J Gastroenterol. 2012; 18(47):7087-7092. 9.Liu WL#, Li XX#, Chu ESH, Go MYY, Xu L, Zhao GJ, Li LL, Dai N, Si JM, Tao Q, Sung JJY and Yu J, Paired Box Gene 5 Is a Novel Tumor Suppressor in Hepatocellular Carcinoma Through Interaction with p53 Signaling Pathway. Hepatology. 2011; 52:843-853. 10.Li XX#, Wong GLH, To KF, Wong VWS, Lai LH, Chow DKL, Lau J YW, Sung JJY, Ding CM, Bacterial Microbiota profiling in Gastritis without Helicobacter pylori infection or Non-Steroidal Anti-Inflammatory Drug Use. PLoS One. 2009; 4(11): e7985.