夏小俊 - 中山大学 - 肿瘤防治中心

个人简介

夏小俊，2007年毕业于美国得克萨斯大学MD安德森癌症中心（University of Texas MD Anderson Cancer Center），获得癌症生物学专业博士，随后在贝勒医学院 (Baylor College of Medicine）和休斯顿卫理会医院研究所（Houston Methodist Research Institute）进行博士后研究和从事讲师工作。现为中山大学肿瘤防治中心，华南肿瘤学国家重点实验室研究员、博士生导师。

研究领域

夏小俊研究员长期从事肿瘤生物学和肿瘤免疫学研究，在天然免疫反应信号通路，肿瘤炎症的分子机制

近期论文

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Feifei Xu#, Zining Wang#, Hongxia Zhang, Jiemin Chen, Xiaojuan Wang, Lei Cui, Chunyuan Xie, Mengyun Li, Fang Wang, Penghui Zhou, Jinyun Liu, Peng Huang, Xiaodong Xia*, Xiaojun Xia*. Mevalonate blockade in cancer cells triggers CLEC9a+ dendritic cell-mediated antitumor immunity. Cancer Res, 2021, Sep 1;81(17):4514-4528. doi: 10.1158/0008-5472.CAN-20-3977. Epub 2021 Jul 15. Zining Wang#,*, Feifei Xu#, Jie Hu, Hongxia Zhang, Lei Cui, Wenhua Lu, Wenzhuo He, Xiaojuan Wang, Mengyun Li, Huanling Zhang, Wenjing Xiong, Chunyuan Xie, Yongxiang Liu, Penghui Zhou, Jinyun Liu, Peng Huang, Xiaofeng Qin, Xiaojun Xia*. Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity. J Immunother Cancer. 2021, May; 9(5): e002155. Doi: 10.1136/jitc-2020-002155. (#, co-first authorship, *, co-correspondence) Hongxia Zhang#, Xinru You#, Xiaojuan Wang, Lei Cui, Zining Wang, Feifei Xu, Mengyun Li, Zhenggang Yang, Jinyun Liu, Peng Huang, Yang Kang, Jun Wu*, Xiaojun Xia*. Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling. PNAS. 2021, Feb 9;118(6):e2005191118. doi: 10.1073/pnas.2005191118. Wang Z, Chen J, Hu J, Zhang H, Xu F, He W, Wang X, Li M, Lu W, Zeng G, Zhou P, Huang P, Chen S, Li W, Xia LP*, Xia X*. cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity. J Clin Invest. 2019 Aug 13;130. pii: 127471. doi: 10.1172/JCI127471.