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个人简介

Ph.D. University of Washington, 2006

研究领域

Nanomaterials and nanotechnology Our research focuses on synthesis and characterization of nanomaterials with multifunctions for biological and environmental applications. Specifically, we will develop new wet chemical methods to synthesize nanomaterials with well-controlled size, shape and composition. We will employ analytical tools in both chemistry and materials science to characterize these nanomaterials. They include UV-vis-NIR, IR, Raman, NMR, Mass spectrometry, as well as powder X-ray diffraction, SEM, TEM, XPS, AFM, and so forth. These nanomaterials are expected to find use in a variety of applications, such as catalysis, fuel cells, disease diagnosis and treatment. We will further study, for example, the effects of different parameters (e.g. size, shape, composition and surface layer) on catalytic and electrocalytic activities of these materials. For biomedical applications, we will emphasize on drug delivery using these nanomaterials through exploration of their bioconjugation, stability, as well as cellular interactions.

近期论文

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Crane, C.C.; Tao, J.; Wang, F.; Zhu, Y.; Chen, J. Mask-Assisted Seeded Growth of Segmented Metallic Heteronanostructures, J. Phys. Chem. C 2014, 118, 28134-28142. (PDF) Beckford, S.; Cai, J.; Chen, J.; Zou, M. Use of Au Nanoparticle-Filled PTFE Films to Produce Low-Friction and Low-Wear Surface Coatings, Tribology Lett. 2014, 56, 223-230. (PDF) Milana L.; Justin N.; Wei, X.; Jenkins, S.V.; Chen, J.; Roper, K.D. Aqueous Dispersion of Plasmonic Hollow Metal Nanoparticles, Materials Lett. 2014, 117, 241-243. (PDF) Srivatsan, A.; Jenkins, S.V.; Jeon, M.; Wu, Z.; Kim, C.;* Chen, J.;* Pandey, R.* Gold Nanocage-Photosensitizer Conjugates for Dual-Modal Image-Guided Enhanced Photodynamic Therapy, Theranostics, 2014, 4, 163-174. (PDF) Jeon, M.; Jenkins, S.V.; Oh, J.; Kim, J.; Peterson, T.; Chen, J.;* Kim, C.* Nonionizing Photoacoustic Cystography with Near-Infrared Absorbing Gold Nanostructures as Optical-Opaque Tracers, Nanomedicine, 2014, 9, 1377-1388. (PDF) Taylor, E.; 2 Chen, S.; Tao, J.; Wu, L.; Zhu, Y.; Chen, J. Synthesis of Pt-Cu Nanodendrites by Controlling Reduction Kinetics for Enhanced Electro-Oxidation of Methanol, ChemSusChem 2013, 6, 1863-1867. (PDF) Chen, S.; Jenkins, S.V.; Tao, J.; Zhu, Y.; Chen, J. Anisotropic Seeded Growth of Cu-M (M = Au, Pt, or Pd) Bimetallic Nanorods with Tunable Optical and Catalytic Properties, J. Phys. Chem. C 2013, 117, 8924-8932. (PDF) Chen, S.; Si, R.; Taylor, E.; Janzen, J.; Chen, J. Synthesis of Pd/Fe3O4 hybrid nanocatalysts with controllable interface and enhanced catalytic activities for CO oxidation, J. Phys. Chem. C 2012, 116, 12969-12976. (PDF) Xia, X.; Yang, M.; Wang, Y.; Zheng, Y.; Li, Q.; Chen, J.;* Xia, Y.* Quantifying the Coverage Density of Poly(ethylene glycol) Chains on the Surface of Gold Nanostructures, ACS Nano 2012, 6, 512-522. Wang, Y.; Xu, J.; Xia, X.; Yang, M.; Vangveravong, S.; Chen, J.; Mach, R.H.; Xia, Y. SV119-Gold Nanocage Conjugates: A New Platform for Targeting Cancer Cell via Sigma-2 Receptors, Nanoscale 2012, 4, 421-424. Li, W.; Cai, X.; Kim, C.; Sun, G.; Zhang, Y.; Deng, R.; Yang, M.; Chen, J.; Achilefu, S.; Wang, L.V.; Xia, Y. Gold Nanocages Covered with Thermally-Responsive Polymers for Controlled Release by High-Intensity Focused Ultrasound, Nanoscale 2011, 3, 1724-1730. Xia, X.; Yang, M.; Oetjen, L.K.; Zhang, Y.; Li, Q.; Chen, J.;* and Xia, Y.* An Enzyme-Sensitive Probe for Photoacoustic Imaging and Fluorescence Detection of Protease Activity, Nanoscale 2011, 3, 950-953. Xia, Y.; Li, W.; Cobley, C. M.; Chen, J.; Xia, X.; Zhang, Q.; Yang, M.; Cho, E. C. and Brown, P. K. Gold Nanocages: From Synthesis to Theranostic Applications, Acc. Chem. Res. 2011, 44, 914-924. Cobley, C. M.; Chen, J.; Cho, E. C.; Wang, L. V. and Xia, Y. Gold Nanostructures: A Class of Multifunctional Materials for Biomedical Applications, Chem. Soc. Rev. 2011, 40, 44-56 (invited tutorial review). Zhang, Q.; Li, W.; Moran, C.; Zeng, J.; Chen, J.; Wen, L. and Xia, Y. Seed-Mediated Synthesis of Ag Nanocubes with Controllable Edge Lengths in the Range of 30-200 nm and Comparison of Their Optical Properties, J. Am. Chem. Soc. 2010, 132, 11372-11378. Kim, C.; Cho, E. C.; Chen, J.; Song, K. H.; Au, L.; Favazza, C.; Zhang, Q.; Cobley, C. M.; Xia, Y. and Wang, L. V. Cancer Targeting in vivo with Bio-Conjugated Gold Nanocages as Monitored and Quantified using Photoacoustic Tomography, ACS Nano 2010, 4, 4559-4564. Chen, J.;* Yang, M.; Zhang, Q.; Cho, E. C.; Cobley, C. M.; Claus, C.; Kim, C.; Wang, L. V.; Welch, M. J. and Xia, Y.* Gold Nanocages: A Novel Class of Multifunctional Nanomaterials for Theranostic Applications, Adv. Funct. Mater. 2010, 20, 3684-3694 (feature article). Tong, L.; Cobley, C. M.; Chen, J.; Xia, Y. and Cheng, J.-X. Bright Three-Photon Luminescence from Au-Ag Alloyed Nanostructures for Bio-imaging with Negligible Phototoxicity, Angew. Chem. Int. Ed. 2010, 49, 3485-3488. Chen, J.;* Claus, C.; Laforest, R.; Zhang, Q.; Yang, M.; Gidding, M.; Welch, M. J.* and Xia, Y.* Gold Nanocages as Photothermal Transducers for Cancer Treatment, Small 2010, 6, 811-817. (*Corresponding authors) Au, L.; Zhang, Q.; Cobley, C. M.; Gidding, M.; Schwartz, A. G.; Chen, J.;* Xia, Y.* Quantifying the Cellular Uptake of Antibody-Conjugated Au Nanocages by Two-Photon Microscopy and Inductively Coupled Plasma Mass Spectrometry, ACSNano 2010, 4, 35-42. (*Corresponding authors)

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