个人简介
现任中山大学附属肿瘤医院影像与微创介入中心教授/主任医师,博士生导师。华南肿瘤学国家重点实验室(2004DA105074)课题组负责人。广东省高等学校“千百十工程”第七批省级培养对象。
研究领域
主要研究方向为定量化影像学诊断与分子影像研究,具备深厚的医学影像学基础及分子生物学研究背景,在磁共振分子影像学研究方面,如磁共振标记基因显像研究、新型磁共振纳米造影剂研发
近期论文
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1. Cao CY, Shen YY, Wang JD, Li L*, Liang GL*. Controlled intracellular self-assembly of gadolinium nanoparticles as smart molecular MR contrast agents. Sci Rep 2013,3,1024 doi:10.1038/srep01024 (2013). 2. Tian XM, Shao YZ, He HQ, Liu H, Shen YY, Huang WL*, Li L*. Nanoamplifiers synthesized from gadolinium and gold nanocomposites for magnetic resonance imaging. Nanoscale 2013, 5(8), 3322-3329 3. Shen Y, Shao Y, He H, Tan Y, Tian X, Xie F*, Li L*. Gadolinium(3+)-doped mesoporous silica nanoparticles as a potential magnetic resonance tracer for monitoring the migration of stem cells in vivo. Int J Nanomedicine 2013,8:119-127 4. Cai HM, Cui CY, Tian HY, Zhang M, Li L*. A novel approach to segment and classify regional lymph nodes on computed tomography images. Comput Math Method M 2012,2012:145926 doi:10.1155/2012/ 145926 5. Shao YZ, Tian XM, Hu WY, Zhang YY, Liu H, He HQ, Shen YY, Xie FK, Li L*. The properties of Gd2O3-assembled silica nanocomposite targeted nanoprobes and their application in MRI. Biomaterials 2012,33(27):6438-6446 6. Feng YP, Liu QC, Zhu JF, Xie FK, Li L*. Efficiency of ferritin as an MRI reporter gene in NPC cells is enhanced by iron supplementation. J Biomed Biotechnol 2012,2012:434878 doi:10.1155/2012/434878 7. Pang YC#, Li L#, Hu WY, Peng YX, Liu LZ, Shao YZ*. Computerized segmentation and characterization of breast lesions in dynamic contrast-enhanced MR images using Fuzzy c-means clustering and snake algorithm. Comput Math Method M 2012,2012:634907 doi:10.1155/2012/634907 (2011 SCI IF 0.684) 8. Cui CY, Cai HM, Liu LZ, Li LR, Tian HY, Li L*. Quantitative analysis and prediction of regional lymph node Status in rectal cancer based on computed tomography imaging. Eur Radiol 2011,21(11):2318-2325 9. Shao YZ, Liu LZ, Song XQ, Cao RH, Liu H, Cui CY, Li X, Bie MJ, Li L*. A novel one-step synthesis of Gd3+ incorporated mesoporous SiO2 nanoparticles for use as an efficient MRI contrast agent. Contrast Media Mol Imaging 2011,6(2):110-118 10. Feng YP, Liu QC, Zhu JF, Xie FK, Li L*. Development and applications of a nasopharyngeal carcinoma Tet-Off cell line. Oncol Lett 2011, 3(2):525-530 11. Shao YZ, Liu LZ, MJ, Li CC, Wu YP, Xie XM, Li L*. Characterizing the clustered microcalcifications on mammograms to predict the pathological classification and grading: a mathematical modeling approach. J Digital Imaging 2011, 24(5):764-771 12. Liu LZ, Liang SB, Li L*, Mao YP, Tang LL, Tian L, Liao XB, Cui CY, Lin AH, Ma J*. Prognostic impact of magnetic resonance imaging-detected cranial nerve involvement in nasopharyngeal carcinoma. Cancer 2009,115(9):1995-2003 13. Cui CY, Liu LZ, Ma J, Liang SB, Tian L, Tang LL, Li L*. Trigeminal nerve palsy in nasopharyngeal carcinoma: Correlation between clinical findings and magnetic resonance imaging. Head Neck 2009,31(6):822-828 14. Li L, Liu LZ, Wu QL, Mo YX, Liu XW, Cui CY, Wan DS*. CT-guided core needle in diagnosis of pancreatic diseases with an automated biopsy gun. J Vasc Interv Radiol 2008,19(1):89-94 15. Ma J, Liu L, Tang L, Zong J, Lin A, Lu T, Cui N, Cui C, Li L*. Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma: prognostic value and staging categories. Clin Cancer Res 2007,13(5):1445-1452 16. Liu LZ, Zhang GY, Xie CM, Liu XW, Cui CY, Li L*. Magnetic resonance imaging of retropharyngeal lymph node metastasis in nasopharyngeal carcinoma: patterns of spread. Int J Radiat Oncol Biol Phys 2006,66(3):721-730 17. Li L, Wu PH, Huang JL, Liu RY, Zeng YX, Huang WL*. Adenovirus-mediated intra-tumoral delivery of the human endostatin gene inhibits tumor growth in nasopharyngeal carcinoma. Int J Cancer 2006,118(8):2064-2071