郑敏 - 中山大学 - 肿瘤防治中心

个人简介

受教育经历： 2000/03 - 2003/05：瑞士苏黎世大学和伯尔尼大学医学院，获双医学博士学位 1999/09 – 2000/03：中山大学肿瘤防治中心在职硕士 1980/09 - 1985/07：南华大学医学院，全日制大学本科毕业工作经历： 2011/12 –现在：中山大学肿瘤防治中心妇科教授、博士导师、主任医生 2004/12 - 2011/12：中山大学肿瘤防治中心妇科副主任医师 1997/12 - 2004/12：中山大学肿瘤防治中心妇科主治医师 1992/05 - 1997/12：先后赴瑞士巴塞尔大学、美国波多黎各大学和美国佛罗里达大学作为访问学者从事科研工作。 1988/04 - 1992/05：中山大学肿瘤防治中心妇科医师 1985/07 - 1988/03：南华大学医学院第一附属医院妇产科医师

研究领域

1．卵巢恶性肿瘤发生发展作用机制及临床意义的研究 2．宫颈癌发生发展相关癌基因的研究

近期论文

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1. Huang L, Zheng M*, Zhou QM, Zhang MY, Jia WH, Yun JP, and Wang HY, Identification of a gene-expression signature for predicting lymph node metastasis in early stage patients with cervical carcinoma, Cancer,117(15):3363-3373, 2011 IF: 5.1 　　2. Zheng M*, Tang L, Huang L, Ding H, Liao WT, Zeng MS and Wang HY, Overexpression of Karyopherin-2 in Epithelial Ovarian Cancer and Correlation With a Poor Prognosis, Obst and Gynecol, 116(4):884-891, 2010 IF: 4.7 　　3. Huang L, Lin J-X, Yu Y-H, Zhang M-Y, Wang H-Y, Zheng M*, Down regulation of Six MicroRNAs Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix, PLoS ONE, 7(3):e33762, 2012 IF:4.1 　　4. He L, Ding H, Wang JH, Zhou Y, Li JD, Huang L, Yun JP, Luo RZ, Yu YH, Jia WH, Zeng MS and Zheng M*, Overexpression of Karyopherin 2 in Human Ovarian Malignant Germ Cell Tumor Correlates with Poor Prognosis, PLoS ONE, 7(9):e42992, 2012 IF: 4.1 　　5. Huang L, Liao LM, Wang HY, Zheng M*, Clinicopathologic character and prognostic factors of the ovarian fibrosarcoma: results of a multi-center retrospective study, BMC cancer, 10:585, 2010 IF: 3.0 　　6. Zheng M*, Huang L, He L, Ding H, Wang HY, and Zheng LM, Evaluation of the effects of type II radical hysterectomy in the treatment of 960 patients with stage IB-IIB cervical carcinoma: a retrospective study, J surg oncol, 103(5):435-441, 2011 IF: 2.4 　　7. Zheng M *, Huang L, Liu JH, Xiong Y, Li JD, Huang X, He L, Ren YF and Wang HY, Type II radical hysterectomy and adjuvant therapy for pelvic lymph node metastasis with stage IB-IIB cervical carcinoma: A retrospective study of 288 patients, J surg oncol, 104(5):480-5, 2011 IF: 2.4 　　8. Huang L, Wang HY, Zhou QM, Zhang MY, Yu YH, Jia WH, Yun JP and Zheng M*, Identification of a 7-Gene Signature that Predicts Relapse and Survival for Early Stage Cervical Carcinoma Patients, Med oncol, 29(4)：2911-2918, 2012 IF: 2.2 　　9. Liao LM, Zheng M*, Huang L, Zhang Y, Wang HY, Molecular characterization of early adenocarcinoma of the uterine cervix by oligonucleotide microarray, Arch Gynecol Obstet, 283(4):861-9, 2011 IF: 1.3 　　10. Huang L, Zheng M*, Liu JH, Xiong Y, Ding H, Tang L,Wang HY, Risk factors and prognosis of IB-IIB cervical carcinoma with common iliac lymph node metastasis, Chin J Cancer，29(4): 300-306, 2010 　　11. Wang J-H#, Chen X-T#, Wen Z-S#, Zheng M, Deng J-M, Wang M-Z, Lin H-X, Chen K, Li J, Yun J-P, Luo R-Z, Song L-B, High Expression of GOLPH3 in Esophageal Squamous Cell Carcinoma Correlates with Poor Prognosis, PLoS ONE,7(10): e45622, 2012 IF: 4.1 　　12. Kocher T, Zheng M, Bolli M, et al. Prognostic relevance of MAGE-A4 tumor antigen expression in transitional cell carcinoma of the urinary bladder: a tissue microarray study. Int J Cancer 2002,100(6):702-5. IF: 4.7 　　13. Zheng M, Simon R, Mirlacher M, et al. TRIO Amplification and Abundant mRNA Expression Is Associated with Invasive Tumor Growth and Rapid Tumor Cell Proliferation in Urinary Bladder Cancer. Am J Pathol 2004, 165(1): 63-9. IF: 6.4 　　14. Zheng M, Simon R, Kononen J, Sauter G, et al. Analysis of gene expression profiles among 3 epithelial ovarian tumor subtypes using cDNA and tissue microarrays. Int J Gyn Cancer 2004,14 (suppl.1):31-32. IF: 1.9 　　15. Zheng M, Kuffler DP. Guidance of regenerating motor axons in vivo by gradients of diffusible peripheral nerve?derived factors. J Neurobiol 2000, 42 (2)212-19. IF: 3.9 　　16. 郑敏, Simon R, Kononen J, Struckmann K, Sauter G, Mihatsch MJ., Moch H。使用cDNA微阵列和组织微阵列对三种上皮性卵巢肿瘤基因表达的分析。癌症2004，23(7):771-776　　