当前位置: X-MOL首页全球导师 国内导师 › 元云飞

个人简介

学习及工作经历: 1978年—1983年:中山医学院医学系,获学士学位 1983年—1986年:中国医学科学院血液学研究所工作 1986年—1989年:中山医科大学外科学硕士研究生,获医学硕士学位 1989年—1998年:中山大学附属肿瘤医院工作 1998年—2000年:Baylor医学院进修学习 2000年—2001年:美国MD Anderson癌症中心进修学习 2001年至今:中山大学附属肿瘤医院肝胆科工作 1962年10月出生。1983年毕业于中山医学院,获学士学位。1983年9月至1986年8月在天津市中国医学科学院血液学研究所工作。1986年9月回母校读研究生,师从著名外科学家王吉甫教授。1989年8月毕业,获医学硕士学位。1989年9月起在中山 医科大学肿瘤医院腹科工作,1998年6月肝胆科成立后一直在肝胆科工作,其中1998.8-2001.8在美国进修学习。1991年晋升为主治医师,1997年晋升为副教授,2004年破格晋升为临床研究员,随后转聘为肿瘤外科教授、主任医师。

研究领域

主要从事肝移植、肝胆胰肿瘤的外科治疗和肝癌的介入治疗。在中国率先应用ICGR15评估肝储备功能,熟练掌握各种复杂的肝切除术(如巨大肝癌切除术、肝尾状叶切除术、扩大半肝切除术,中肝叶切除术)、高位胆管癌根治术和胰十二指肠切除术等,对各种高难度肝胆外科手术及高危患者的围手术期处理积累了丰富的经验。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

(1) Yunfei Yuan, Richard Mendez, Aysegul Sahin, and Jia Le Dai*. Hypermethylation leads to silencing of the SYK gene in human breast cancer. Cancer Research 2001, 61(14):5558-5561. (2001 IF=8.302) (2) Yunfei Yuan, Hongji Liu, Aysegul Sahin and Jia Le Dai*. Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness. International Journal of Cancer 2005, 113(4):654–659. (2005 IF=4.7) (3) Yunfei Yuan*, Jianping Wang, Jinqing Li, Li Wang, Meixiang Li, Zuli Yang, Changqing Zhang, and Jia Le Dai. Frequent Epigenetic Inactivation of Spleen Tyrosine Kinase Gene in Human Hepatocellular Carcinoma. Clinical Cancer Research 2006, 12(22):6687-6695. (2006 IF=6.177) (4) Christina Pramudji, Satoru Shimura, Shin Ebara, Guang Yang, Jianxiang Wang, Chengzhen Ren, Yunfei Yuan, Salahaldin A. Tahir, Terry L. Timme, and Timothy C. Thompson*. In Situ Prostate Cancer Gene Therapy Using a Novel Adenoviral Vector Regulated by the Caveolin-1 Promoter. Clinical Cancer Research, 2001, 7(12):4272-4279.2008: (5) Li Xu, Liang Huang, Bin-kui Li, Ya-qi Zhang, Jin-qing Li, Yun-fei Yuan*. Clinicopathologic Features and Long-Term Outcomes of Chinese Patients with Hepatocellular Carcinoma in Non-Cirrhotic Liver. Digestive Surgery 2008, 25(5):376. (2008 IF=1.257) (6) Hang Su, Jing Zhao, Yujuan Xiong, Teng Xu, Fan Zhou, Yunfei Yuan, Ying Zhang, Shi-Mei Zhuang*. Large-scale analysis of the genetic and epigenetic alterations in hepatocellular carcinoma from Southeast China. Mutation Research 2008, 641:27-35. (7) Xing-Dong Xiong, Jian-Hong Fang, Fu-En Qiu, Jing Zhao, Jiasen Cheng, Yunfei Yuan, Sheng-Ping Li, Shi-Mei Zhuang*. A novel functional polymorphism in the Cdc6 promoter is associated with the risk for hepatocellular carcinoma. Mutation Research, 2008, 643:70-74. (8) Teng Xu, Ying Zhu, Qing-Kun Wei, Yunfei Yuan, Fan Zhou, Yi-Yuan Ge,JR Yang, H Su, Shi-Mei Zhuang*. A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis 2008, 29(11):2126-2131. (9) Hang Su, Jian-Rong Yang, Teng Xu, Jun Huang, Li Xu, Yunfei Yuan*, Shi-Mei Zhuang*. MicroRNA-101, Downregulated in Hepatocellular Carcinoma, Promotes Apoptosis and Suppresses Tumorigenicity. Cancer Research 2009, 69(3):1135-42. (2009 IF=7.543) (10) Jun Huang, Bin-Kui Li, Gui-Hua Chen, Jin-Qing Li, Ya-Qi Zhang, Guo-Hui Li, Yun-fei Yuan*. Long-Term Outcomes and Prognostic Factors of Elderly Patients with Hepatocellular Carcinoma Undergoing Hepatectomy. Journal of Gastrointestinal Surgery 2009, 13(9):1627-1635. (2009 IF=2.402) (11) Binkui Li, Wenji Liu, Li Wang, Meixiang Li, Jianping Wang, Liang Huang, Pinzhu Huang, and Yunfei Yuan*. CpG Island Methylator Phenotype Associated with Tumor Recurrence in Tumor-Node-Metastasis Stage I Hepatocellular Carcinoma. Annals of Surgical Oncology, 2010, 17(7):1917-1926. (2010 IF=4.182) (12) Binkui Li, Yunfei Yuan*, Guihua Chen, Liru He, Yaqi Zhang, Jinqing Li, Guohui Li, and Wan Yee Lau. Application of tumor-node-metastasis staging 2002 version in locally advanced hepatocellular carcinoma: is it predictive of surgical outcome? BMC Cancer. 2010, 10:535-43. (2010 IF=3.153) (13) Yu-Xiong Feng, Jiang-Sha Zhao, Jing-Jing Li, Tao Wang, Shu-Qun Cheng, Yunfei Yuan, Fudi Wang, Xiao-Fan Wang, Dong Xie*. Liver Cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF- B signaling pathway. Hepatology, 2010, 51(2):535-544. (14) Chunxian Zeng, Ruizhi Wang, Daochuan Li, Xue-Jia Lin, Qing-Kun Wei, Yunfei Yuan, Qing Wang, Wen Chen, and Shi-Mei Zhuang*. A Novel GSK-3 beta–C/EBP alpha–miR-122–Insulin-Like Growth Factor 1 Receptor Regulatory Circuitry in Human Hepatocellular Carcinoma. Hepatology 2010, 52:1702-1712. (15) Leilei Chen, Tim Hon Man Chan, Yun-Fei Yuan, Liang Hu, Jun Huang, Stephanie Ma, Jian Wang, Sui-Sui Dong, Kwan Ho Tang, Dan Xie, Yan Li, and Xin-Yuan Guan*. CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. The Journal of Clinical Investigation. 2010, 120(4):1178-91. (16) Hongxing Zhang, Yun Zhai, Zhibin Hu, Chen Wu, Ji Qian, Weihua Jia, Fuchao Ma, Wenfeng Huang, Lixia Yu, Wei Yue, Zhifu Wang, Peiyao Li, Yang Zhang, Renxiang Liang, Zhongliang Wei, Ying Cui, Weimin Xie, Mi Cai, Xinsen Yu, Yunfei Yuan, Xia Xia, Xiumei Zhang, Hao Yang, Wei Qiu, Jingmin Yang, Feng Gong, Minshan Chen, Hongbing Shen, Dongxin Lin, Yi-Xin Zeng, Fuchu He* & Gangqiao Zhou*. Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers. Nature Genetics. 2010, 42(9):755-8. (17) Ming Shi, Ji-An Chen, Xiao-Jun Lin, Rong-Ping Guo, Yun-Fei Yuan, Min-Shan Chen, Ya-Qi Zhang, Jin-Qing Li*. Transarterial chemoembolization as initial treatment for unresectable hepatocellular carcinoma in southern China. World Journal of Gastroenterology 2010, 16(2): 264-269. (18) Guo-Liang Huang, Bin-Kui Li, Mei-Yin Zhang, Hui-Zhong Zhang, Rong-Rong Wei, Yun-Fei Yuan, Ming Shi, Xiao-Qian Chen, Long Huang, An-Hua Li, Bi-Jun Huang, Hong-Hua Li, Hui-Yun Wang*. LOH analysis of genes around D4S2964 identifies ARD1B as a prognostic predictor of hepatocellular carcinoma. World Journal of Gastroenterology 2010, 16(16): 2046-2054.

推荐链接
down
wechat
bug