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个人简介

现任中山大学(原中山医科大学)肿瘤防治中心妇科主任、宫颈癌诊治单病种管理首席专家。1984年7月毕业于中山医科大学医学系,在该校附属肿瘤医院妇科从事临床医疗工作至今。1993年在中山医科大学获医学硕士学位, 2004年在澳大利亚悉尼大学获博士学位。1997年10月起任妇科副主任,2004年10月至2008年10月任中山大学肿瘤医院副院长,主管科研和信息工作。2006年11月起兼任妇科主任。擅长对早期妇科恶性肿瘤保留生育功能的治疗和对晚期及复发性妇科恶性肿瘤的诊治。在国外留学期间,主要进行了宫颈癌及其癌前病变病因学的分子流行病学研究,对人乳头状瘤病毒(HPV)感染与宫颈癌的关系进行了深入的研究,并系统了解了国外妇科肿瘤的临床诊治现状。回国后,将国外先进的经验应用于临床实践,开展规范化诊治,并积极探索对晚期及复发性妇科恶性肿瘤的个体化诊治策略。同时,致力于开展宫颈癌的预防工作,热心公益活动。研究方向为宫颈癌和卵巢癌的分子分期和淋巴结转移相关问题。 一、基本情况   职称:主任医师、教授、博士生导师、宫颈癌首席专家   职务:妇科主任   专家门诊时间:周一下午、周三上午   专业特长:擅长对早期妇科恶性肿瘤保留生育功能的治疗和对晚期及复发性妇科   恶性肿瘤的诊治。 二、学习及工作经历:   1979年—1984年:中山医科大学就读   1990年—1993年:中山医科大学附属肿瘤医院就读硕士研究生   2001年—2004年:悉尼大学就读博士研究生   1984年至今:中山大学附属肿瘤医院工作

研究领域

研究方向为宫颈癌和卵巢癌的分子分期和淋巴结转移相关问题。

近期论文

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1.Feng Y, He F, Yan S, Huang H, Huang Q, Deng T, Wu H, Gao B, Liu J(*). The Role of GOLPH3L in the Prognosis and NACT response in Cervical Cancer. J Cancer. 2017 Feb 10;8(3):443-454 2.Gu H, Li J, Gu Y, Tu H, Zhou Y, Liu J(*). Survival Impact of Ovarian Preservation on Women With Early-Stage Endometrial Cancer:A Systematic Review and Meta-analysis. International Journal of Gynecological Cancer.2017 Jan;27(1):77-84. 3.Feng Y, Cao T, Wang Y, Huang H, Xie Y, Liu J(*). Neoadjuvant chemotherapy followed by conization to spare fertility in cases of locally advanced cervical cancer:A case report and review of the literature. Mol Clin Oncol. 2016 Oct;5(4):411-416 4.Gu H, Li J, Gu Y, Tu H, Zhou Y, Liu J(*). Survival Impact of Ovarian Preservation on Women With Early-Stage Endometrial Cancer:A Systematic Review and Meta-analysis. Int J Gynecol Cancer. 2017 Jan;27(1):77-84 5.Tu H, Xiong Y, Huang H, Huang Y, Wan T, Deng T, Liu J(*). Individualized Treatment of Patients With Early-Stage Epithelial Ovarian Cancer After Incomplete Initial Surgery. Int J Gynecol Cancer. 2016 Jan;26(1):73-81 6.Chunyan Lan, Xin Huang, Qidan Huang, Yin Wang, Haifeng Gu, Yong Li, Jihong Liu(*). "Should the Optimal Adjuvant Treatment for Patients With Early-Stage Endometrial Cancer With High-Intermediate Risk Factors Depend on Tumor Grade?" Int J Gynecol Cancer 2015;25: 1445-1452 7.Chunyan Lan, Andreas Heindl, Xin Huang, Shaoyan Xi, Susana Banerjee, Jihong Liu(*), and Yinyin Yuan. Quantitative histology analysis of the ovarian tumour microenvironment. Sci Rep. 2015; 5: 16317. 8.Tiefeng Cao, Yanling Feng, Qidan Huang, Ting Wan, and Jihong Liu(*). Prognostic and Safety Roles in Laparoscopic Versus Abdominal Radical Hysterectomy in Cervical Cancer:A Meta-analysis. J Laparoendosc Adv Surg Tech A.2015 Dec;25(12):990-8 9.Yong-Wen Huang,* Yun Zhou,* Chun-Yan Lan,Yin Wang,Yan-Ling Feng, Rong-Zhen Luo, and Ji-Hong Liu(*). Tumor-induced VEGF-C overexpression in retroperitoneal lymph nodes in VX2 carcinoma-bearing rabbits. Drug Des Devel Ther. 2015; 9: 5949–5956. 10.Yanling Feng, Fan He, Huini Wu, He Huang, Lan Zhang, Xian Han, Jihong Liu(*)GOLPH3L is a Novel Prognostic Biomarker for Epithelial Ovarian Cancer. Journal of Cancer 2015; 6(9): 893-900. 11.Deng T, Feng Y, Zheng J, Huang Q, Liu J(*). Low initial human papillomavirus viral load may indicate worse prognosis in patients with cervical carcinoma treated with surgery. J Gynecol Oncol. 2015;26:111-7. 12.Lan C, Huang X, Huang Y, Xi S, Huang H, Feng Y, Liu J(*).The outcome and efficacy of adjuvant chemotherapy alone in patients with stage IIIA endometrial carcinoma with solitary adnexal involvement: A retrospective single-institution study..Gynecol Oncol. 2014, 135(3):446–450 13.Lan Zhang, He HuangLongjuan Zhang, Teng Hou, Shu Wu, Qidan Huang, Libing Song(*),Jihong Liu(*).URG4 overexpression is correlated with cervical cancer progression and poor prognosis in patients with early-stage cervical cancer. BMC Cancer. 2014, 14(1):1-11 14.顾海风, 刘继红. 子宫颈癌前哨淋巴结的研究进展. 中华妇产科杂志,2014,10,49(10):798-800. 15.熊樱, 刘继红. P53凋亡刺激蛋白抑制因子在人类恶性肿瘤的研究进展. 妇产与遗传2014,4(1):41-4. 16.孙 菲, 李艳芳, 刘继红, 熊 樱. 208例低危型宫颈癌患者的辅助治疗及预后相关因素分析. J South Med Univ, 2014, 34(3): 401-405. 17.Huang H, Li YJ, Lan CY, Huang QD, Feng YL, Huang YW, Liu JH(*). Clinical significance of ascites in epithelial ovarian cancer. Neoplasma. 2013;60(5):546-52. 18.Shi Y, Li L, Hu Z, Li S, Wang S, Liu J(*), etc. A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12. Nat Genet. 2013 Aug;45(8):918-22.(共同第一作者) 19.Lan C, Huang X, Cao X, Huang H, Feng Y, Huang Y, Liu J(*). Adjuvant docetaxel and carboplatin chemotherapy administered alone or with radiotherapy in a "sandwich" protocol in patients with advanced endometrial cancer: a single-institution experience. Expert Opin Pharmacother. 2013;14(5):535-42. 20.Huang Q, Huang H, Wan T, Deng T, Liu J(*). Clinical outcome of 31 patients with primary malignant melanoma of the vagina. J Gynecol Oncol. 2013 ;24(4):330-5. 21.Huang YW, Guan MF, Liu JH, Lan CY, Wan T, Huang X. Large animal model for retroperitoneal lymphatic and lung metastasis.Mol Med Rep. 2013;8(6):1617-22. 22.Lan C, Huang X, Lin S, Huang H, Cai Q, Wan T, Lu J, Liu J(*). Expression of M2-Polarized Macrophages is Associated with Poor Prognosis for Advanced Epithelial Ovarian Cancer. Technol Cancer Res Treat. 2013;12(3):259-67. 23.Lan C, Huang X, Lin S, Huang H, Cai Q, Lu J, Liu J(*).High density of IL-17-producing cells is associated with improved prognosis for advanced epithelial ovarian cancer. Cell Tissue Res. 2013 May;352(2):351-9. 24.Xiong Y, Liu JH, Zheng M, Cao LP, Liang LZ. Use of preoperative clinicopathologic characteristics to identify patients with low-risk cervical cancer suitable for Piver class II radical hysterectomy. INT J GYNECOL OBSTET. 2013 Apr 1. pii: S0020-7292(13)00138-0. 25.Li Z, Yu CP, Zhong Y, Liu TJ, Huang QD, Zhao XH, Huang H, Tu H, Jiang S, Zhang Y, Liu JH(*)& Song LB(*). Sam68 expression and cytoplasmic localization is correlated with lymph node metastasis as well as prognosis in patients with early-stage cervical cancer. Ann Oncol. 2012 Mar;23(3):638-46. Epub 2011 Jun 23. 26.Huang YW, Zeng Z, Li S, Liu JH(*). Differential routes of carboplatin administration influence lymphocyte apoptosis in retroperitoneal lymph nodes. Tumour Biol. 2012 Dec;33(6):2053-9. 27.Lan C, Huang X, Lin S, Cai M, Liu J(*). Endometrial Stromal Sarcoma Arising from Endometriosis: A Clinicopathological Study and Literature Review. Gynecol Obstet Invest 2012;74:288-297. 28.Huang H, Li Y, Liu J(*), Zheng M, Feng Y, Hu K, Huang Y, Huang Q. Screening and identification of biomarkers in ascites related to intrinsic chemoresistance of serous epithelial ovarian cancers. PLoS One. 2012;7(12):e51256. doi: 10.1371/journal.pone.0051256. Epub 2012 Dec 10. 29.Ying Xiong, Li-Ping Cao , Hui-Lan Rao , Mu-Yan Cai ,Li-Zhi Liang , Ji-Hong Liu(*). Clinical significance of peritumoral lymphatic vessel density and lymphatic vessel invasion detected by D2-40 immunostaining in FIGO Ib1-IIa squamous cell cervical cancer. Cell Tissue Res (2012) 348:515–522 30.Xiong Y, Liang LZ, Cao LP, Min Z, Liu JH(*). Clinical effects of irinotecan hydrochloride in combination with cisplatin as neoadjuvant chemotherapy in locally advanced cervical. Gynecol Oncol. 2011 Oct;123(1):99-104. Epub 2011 Jul 8. 31.Huang H, Liu J(*), Li Y, Wan T, Feng Y, Li Z, Huang Q.Metastasis to deep obturator and para-aortic lymph nodes in 649 patients withcervical carcinoma. Eur J Surg Oncol. 2011 Nov;37(11):978-83. Epub 2011 Sep 9. 32.Liu JH, B Rose,Huang X, Liao GW, J Carter, Wu XJ, C Thompson , Comparative analysis of characteristics of women with cervical cancer in high- versus low- incidence regions Gynecologic Oncology 2004,3(94):803-810 33.Yang GF, Xie D, Liu JH, Luo JH, Li LJ, Hua WF, Wu HM, Kung HF, Zeng YX, Guan XY. Expression and amplification of eIF-5A2 in human epithelial ovarian tumors and overexpression of eJF-5A2 is a new independent predictor of outcome in patients with ovarian carcinoma. Gynecology Oncology,2008. 34.Li W, C Thompson, Y E Cossart, C J O’Brien, Liu JH, R A Scolyer, J Carter, C Dalrymple, B Rose. The site of infection and ethnicity of the patient influence the biological pathways to HPV-induced mucosal cancer Modern Pathology 2004, 17:1031-1037 35.黄绮丹,黄鹤,刘继红. 64 例 Ⅳ期上皮性卵巢癌的临床分析. 热带医学杂志,2013,1,13(1):79-82 36.涂画,黄鹤,黄绮丹,李政,冯艳玲,刘继红(*).卵巢上皮性癌患者术后单纯淋巴结区域复发的治疗及预后分析. 中华妇产科杂志,2012,12,47(12):928-33 37.李玉洁,黄鹤,刘继红(*),蓝春燕.三阶梯技术在436例宫颈病变中的应用价值探讨. 实用妇产科杂志. 2012.28(1):53-56. 38.陈鹏,曾峥,黄鹤,涂画,刘继红(*). 吲哚胺-2,3-双加氧酶在卵巢浆液性腺癌中的表达及临床意义. 中国实用妇科与产科杂志. 2012.28(增刊):20-22 39.李明伟, 刘继红(*).TrkB及其配体BDNF在卵巢上皮癌中的表达及其临床意义. 中国妇产科临床杂志 2012,13(2):122-125

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