个人简介
教育经历
2011-2013, 美国马里兰大学化学与生物化学系,访问学者
2007-2013, 华东师范大学, 有机化学专业, 博士
2003-2007, 大连理工大学, 制药工程专业, 学士
工作经历
2017-至今,中山大学,药学院,副教授
2016-2017,华东师范大学,化学与分子工程学院,副研究员
2013-2016,上海药明康德新药研发有限公司, 国际新药研发部项目组长
研究领域
主要从事通过设计开发高效合成新方法在抗感染及肿瘤领域进行药物开发与研究。
近期论文
查看导师最新文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
Liu Hu#, Xing Cai#, Suzhen Dong#, Yongjia Zhen, Jidi Hu, Shenjun Wang, Jingwen Jiang, Jiawu Huang, Yuqiao Han, Yu Qian*, Yanqiu Yuan*, Wenhao Hu, “Synthesis and Anticancer Activity of Novel Actinonin Derivatives as HsPDF Inhibitors” J. Med. Chem. 2020, 63, 6959-6978.
Alavala Gopi Krishna Reddy, Pedireddi Niharika, Su Zhou, Shi-Kun Jia, Taoda Shi, Xinfang Xu, Yu Qian*, Wenhao Hu* “Brønsted Acid Catalyzed Enantioselective Assembly of Spirochroman-3,3-oxindoles” Org. Lett. 2020,22,2925-2930.
Xinru Yin, Aimin Xu, Jidi Hu, Ming Bao, Wenhao Hu*, Yu Qian*, “A Rh(II)/phosphoric acid co-catalyzed three-component reaction of diazo-ketones with alcohols and azonaphthalenes: access to indole derivatives via a formal [3 + 2]-cycloaddition”, Org. Biomol. Chem. 2020, 18, 9805-9809.
Kai Zhou, Ming Bao, Jingjing Huang, Zhenghui Kang, Xingfang Xu, Wenhao Hu*, Yu Qian*, “Iron-catalyzed [3+2]-cycloaddition of in situ generated N-ylides with alkynes or olefins: access to multi-substituted/polycyclic pyrrole derivatives” Org. Bio. Chem, 2020, 18, 409-414.
Kuiyong Dong, Chao Pei, Q. Zeng, Lihua Qiu, Wenhao Hu, Yu Qian*, Xingfang Xu*, “Copper-catalyzed [4+1]-annulation of 2-alkenylindoles with diazoacetates: a facile access to dihydrocyclopenta [b]indoles” Chem. Commun. 2019, 55(45), 6393-6396.
Chao Pei, Cheng Zhang, Yu Qian*, Xinfang Xu*,“Catalytic carbene/alkyne metathesis (CAM): a versatile strategy for alkyne bifunctionalization”, Org. Bio. Chem, 2018, 16, 8677-8685.
Xichen Xu#,Yu Qian#,Peter Y. Zavalij, Michael P. Doyle*,“Selective catalyst-dependent competitive 1,2-C→C, -O→C and -N→C migrations from β-methylene-β-silyloxy-β-amido-α-diazoacetates”, J. Am. Chem. Soc. 2013, 135, 1244−1247.
Yu Qian, Xinfang Xu, Xiaochen Wang, Peter J. Zavalij, Wenhao Hu, Michael P. Doyle*, “Rhodium(II)- and Copper(II)-Catalyzed Reactions of Enol Diazoacetates with Nitrones: Metal Carbene versus Lewis Acid Directed Pathways”, Angew. Chem. Int. Ed. 2012, 51, 5900-5903.