个人简介
教育经历 2007年9月至2012年7月:理学博士,药物化学专业,四川大学华西药学院,导师:陈应春教授 2003年9月至2007年7月:理学学士,药学专业,四川大学华西药学院 工作经历 2015年1月至2016年11月:助理教授,丹麦哥本哈根大学 2012年9月至2015年1月:博士后,丹麦哥本哈根大学,合作导师:Kristian Strømgaard教授
研究领域
主要为有机合成方法学研究、不对称合成、多肽药物化学等。
近期论文
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1. Xiao-Feng Xiong, Hang Zhang, Christina R. Underwood, Kasper Harpsøe, Thomas J. Gardella, Mie F. Wöldike, Micheal Mannstadt, David. E. Gloriam, Hans Bräuner-Osore, Kristian Strømgaard. “Total synthesis and structure-activity relationship study of a series of selective Gq protein inhibiotrs “. Nature Chemistry. 2016, 8, 1035-1041. 2. Xiao-Feng Xiong, Mette H. Poulsen, Rama Ashraf, Niels G. Nørager, Kristian Strømgaard, “Structure-activity relationship study of spider polyamine toxins as inhibitors of ionotropic glutamate receptors“. ChemMedChem, 2014, 9, 2661-2670. 封面文章 3. Xiao-Feng Xiong, Quan Zhou, Jing Gu, Lin Dong, Tan-Yu Liu, Ying-Chun Chen, “Trienamine Catalysis with 2,4-Dienones: Development and Application in Asymmetric Diels-Alder Reaction”, Angew. Chem. Int. Ed. 2012, 51, 4401-4404. VIP及封面文章 4. Xiao-Feng Xiong, Hang Zhang, Jing Peng, and Ying-Chun Chen, “Direct Asymmetric Michael Addition of cyclic N-sulfonylimines to α,β-Unsaturated Aldehydes”, Chem. Eur. J. 2011, 17, 2358-2360. 5. Xiao-Feng Xiong, Zhi-Jun Jia, Wei Du, Kun Jiang, Tian-Yu liu, Ying-Chun Chen, “Merging chiral organocatalysts: enantio- and diastereoselective directvinylogous Mannich reaction of alkylimines”, Chem. Commun. 2009, 6994-6996. 6. Kelly L Roszko, Bi Ruiye, Caroline Gorvin, Hans Bräuner-Osborne, Xiao-Feng Xiong, Asuka Inoue, Rajesh V Thakker, Kristian Strømgaard, Thomas Gardella, Michael Mannstadt, "Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors", JCI Insight, 2017, 2(3):e91079. doi:10.1172/jci.insight.91079 7. Hang Zhang, Xiao-Feng Xiong, Michael W. Boesgaard, Christina R. Underwood, Hans Bruner-Osborne, and Kristian Strømgaard. "Structure–Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the Gq Protein", ChemMedChem, 2017, DOI: 10.1002/cmdc.201700155. 8. Bo Han, Qing-Ping Liu, Rui Li, Xu Tian, Xiao-Feng Xiong, Jing-Gen Deng, Ying-Chun Chen, “Discovery of Bifunctional Thiourea/Secondary-Amine Organocatalysts for the Highly Stereoselective Nitro-Mannich Reaction of α-Substituted Nitroacetates”, Chem. Eur. J. 2008,14 , 8094-8097.