个人简介
薛箭飞,副研究员,博士,毕业于北京协和医学院,现为中山大学孙逸仙纪念医院肿瘤学科博士生导师。
研究领域
主要从事蛋白翻译后修饰在肿瘤信号传导中的作用研究。
近期论文
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1. Xue J, Lin X, Chiu WT, Chen YH, Yu G, Liu M, Feng XH, Sawaya R, Medema RH, Hung MC, Huang S*. Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis. J Clin Invest. 2014; 124(2):564-79. 2. Xue J#, Chen Y#, Wu Y, Wang Z, Zhou A, Zhang S, Lin K, Aldape K, Majumder S, Lu Z, Huang S*. Tumour suppressor TRIM33 targets nuclear β-catenin degradation. Nat Commun. 2015; 6:6156. Chen Y#, Li Y#, Xue J#, Gong A, Yu G, Zhou A, Lin K, Zhang S, Zhang N, Gottardi CJ, Huang S. Wnt-induced deubiquitination FoxM1 ensures nucleus β-catenin transactivation. EMBO J. 2016;35(6):668-84。 3. Xue J#, Zhou A#, Wu Y#, Morris SA, Lin K, Amin SB, Verhaak R, Fuller GN, Xie K, Heimberger AB, Huang S*. STAT3 activation promotes glioma tumorigenesis by inducing miR-182-5p. Cancer Res. 2016; Epub ahead of print 4. Xue J*, Zhou A, Tan C, Wu Y, Lee H-T, Li W, Xie K, Huang S*. Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression. J Biol Chem. 2015;290(30):18662-70. 5. Lee HT#, Xue J#, Chou PC, Zhou A, Yang P, Conrad CA, Aldape KD, Priebe W, Patterson C, Sawaya R, Xie K, Huang S*. Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells. Oncotarget. 2015; 6(12):10016-29.