个人简介

B.S., University of California, Los Angeles (1986): Chemistry M.S., California State Polytechnic University, Pomona (1988): Chemistry Advisor: Joseph Sneddon Ph.D., University of California, Riverside (1993): Analytical Chemistry Advisor: Werner G. Kuhr Postdoctoral Associate, Ecole Normale Superieure, Paris, France (1993–94) Advisor: Christian Amatore Postdoctoral Associate, Tufts University (1994-96) Advisor: David R. Walt

研究领域

Bioanalytical Chemistry, Bionanotechnology

Our work involves improving the accuracy of nanomaterial toxicity assessments, and advancing the diagnostic and therapeutic applications of nanomaterials. Our areas of expertise include the physiochemical characterization of nanomaterials, the reproducible preparation of purified nanomaterial samples, and direct measurements of metal oxide and carbon nanomaterials inside mammalian cells and aquatic organisms. We are also interested in developing label-free methods to detect carbon nanomaterial contamination in workplace areas.

近期论文

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R.K. Draper, C.A. Mikoryak, R.-H. Wang and P. Pantano, Method to Measure Carbon Nanotubes Taken-Up by a Plurality of Living Cells, U.S. Patent Application No. 2011/0203927 (published 25 August 2011). K.J. Balkus, Jr., P. Pantano, C.C. Meek and D.H. Coutinho, Encoded Molecular Sieve Particle-based Sensors, U.S. Patent 6,790,672 (awarded 14 September 2004). P. Pantano, S.S. Khan, E.S. Jin and H.W. Stokes, Jr., Thin Film Fiber Optic Electrode Sensor Array and Apparatus for Concurrent Viewing and Chemical Sensing of a Sample, U.S. Patent 6,487,326 (awarded 26 November 2002). D.R. Walt and P. Pantano, Superresolution Imaging Fiber for Subwavelength Light Energy Generation and Near-Field Optical Microscopy, U.S. Patent 5,633,972 (awarded 27 May 1997). Wang, R.; Hughes, T.; Beck, S.; Vakil, S.; Li, S.; Pantano, P. and Draper, R.K. Generation of Toxic Degradation Products by Sonication of Pluronic® Dispersants: Implications for Nanotoxicity Testing, Nanotoxicology (Early Online), 1-10 (2012). Pantano, P.; Draper, R.K.; Mikoryak, C. and Wang, R. Electrophoretic Methods to Quantify Carbon Nanotubes in Biological Cells, in Handbook of Carbon Nano Materials, F. D’Souza and K. M. Kadish, Eds.; World Scientific Publishers, Singapore, Vol. 3, pp. 83-106 (2012). Sheardy, A.T.; Taylor, J.J.; Chilek, J.L.; Li, S.; Wang, R.; Draper, R.K and Pantano, P. Study of the Near Infrared Heating of Dispersions of Protein-coated Pristine and Carboxylated Single-Walled Carbon Nanotubes, International Journal of Nanoscience, 11, 1250034 (2012). Jacobsen, N.J. and Pantano, P. Determining the Percentages of Semiconducting and Metallic Single-Walled Carbon Nanotubes in Bulk Soot, Carbon 49, 1998-2006 (2011). Wang, R.; Mikoryak, C.; Li, S.; Bushdiecker II, D.; Musselman, I.H.; Pantano, P. and Draper, R.K. (2011) Cytotoxicity Screening of Single-Walled Carbon Nanotubes: Detection and Removal of Cytotoxic Contaminants from Carboxylated Carbon Nanotubes, Molecular Pharmaceutics 8, 1351-1361 (2011). Marches, R.; Mikoryak, C.; Wang, R.; Pantano, P.; Draper, R.K. and Vitetta, E.S. The Importance of Cellular Internalization of Antibody-Targeted Carbon Nanotubes in the Photothermal Ablation of Breast Cancer Cells, Nanotechnology 22, 095101 (2011). Marches, R.; Chakravarty, P.; Bajaj, P.; Musselman, I.H.; Pantano, P.; Draper, R.K. and Vitetta, E.S. Specific Thermal Ablation of Tumor Cells using a Monoclonal Antibody Covalently Coupled to a Single-Walled Carbon Nanotube, International Journal of Cancer 125, 2970-2977 (2009). Katari, S.C.; Wallack, M.; Hubenscmidt, M.; Pantano, P. and Garner, H.R. Fabrication and Evaluation of a Near-Infrared Hyperspectral Imaging System, Journal of Microscopy 236, 11-17 (2009). R. Wang, C. Mikoryak, E. Chen, S. Li, P. Pantano and R.K. Draper, Gel Electrophoresis Method to Measure the Concentration of Single-Walled Carbon Nanotubes Extracted from Biological Tissue, Analytical Chemistry 81, 2944-2952 (2009). P. Chakravarty, R. Marches, N.S. Zimmerman, A.D.-E. Swafford, P. Bajaj, I.H. Musselman, P. Pantano, R.K. Draper and E.S. Vitetta, Thermal Ablation of Tumor Cells with Antibody-Functionalized Single-Walled Carbon Nanotubes, Proceedings of the National Academy of Science, USA 105, 8697-8702 (2008). H.N. Yehia, R.K. Draper, C. Mikoryak, E.K. Walker, M.C. Daigrepont, I.H. Musselman, P. Bajaj, G.R. Dieckmann and P. Pantano, Single-Walled Carbon Nanotube Interactions with HeLa Cells, Journal of Nanobiotechnology 5, 8-24 (2007). K.A. Hartzell, K.L. Danowski and P. Pantano, Combined Imaging and Chemical Sensing with a Disposable Microscope Objective Chemical Sensor, Applied Spectroscopy Reviews 43, 1-21 (2007). S.-F. Chin, R.H. Baughman, A.B. Dalton, G.R. Dieckmann, R.K. Draper, C. Mikoryak, I.H. Musselman, V.Z. Poenitzsch, H. Xie and P. Pantano, Amphiphilic Helical Peptide Enhances the Uptake of Single-Walled Carbon Nanotubes by Living Cells, Experimental Biology and Medicine 232, 1236-1244 (2007). S.-F. Chin and P Pantano, Antibody-Modified Microwell Arrays and Photobiotin Patterning on Hydrocarbon-Free Glass, Microchemical Journal 84, 1-9 (2006). P. Zhao, Y. Zhao, A. D. Sherry and P. Pantano, Concurrent 31P Nuclear Magnetic Resonance Spectroscopy and Fiber-Optic Oxygen Consumption Measurements in Perfused Rat Hearst, Methods in Enzymology 381, 735-746 (2004). S.E. Carranza and P. Pantano, Fluorescence Microscopy and Flow Cytofluorometry of Reactive Oxygen Species, Applied Spectroscopy Reviews 38, 245-261 (2003).