个人简介
Education Experience：
1983-1988 B.Sc. Chemistry Leiden University
1984-1986 M.S. Western philosophy Leiden University
1990-1994 Ph. D. Organic Chemistry Leiden University
Professional Experience：
2016- Distinguished Perennial Guest Professor Tianjin University
1996-1997 NWO Talent Postdoc Columbia University
1997-2006 Assistant and Associate Professor Wageningen University
2007- Personal Chair in Organic Chemistry Wageningen University
2008-2016 Chair of Organic Chemistry Wageningen University
2011-2016 Distinguished Adjunct Professor of Chemical and Ma King Abdulaziz University
Honors and Awards：
2014 – present: Perennial Distinguished Guest Professor, Tianjin University, Tianjin, China.
2013 – 2014: Joseph Meyerhoff Visiting Professor, Weizmann Institute, Rehovot, Israel.
2011 – present: Distinguished Adjunct Professor, King Abdulaziz University, Jeddah, Saudi Arabia.
Spring 2007: Visiting Professor at Stanford University, Stanford, California, USA.
Oct. 2005: Visiting Professor to Lanzhou University, Lanzhou, China.
Summer 2003: Visiting Fellow to the National Canadian Nanotechnology Institute, Ottawa, Canada.
Fall 2002: Emerson Visiting Research Fellow at Emory University, Atlanta, Georgia, USA.
1994 – 1995: Postdoctoral Talent Fellowship (NWO).
1994: L. J. Oosterhoff Award (L. J. Oosterhoff Fund, administered by Leiden University).
1988 – 1989: Netherlands Ramsay Memorial Fellowship (Royal Netherlands Academy of Sciences).
研究领域
I am interest in the development of surface-bound organic chemistry, meaning organic reactions taking place at or near the confinement of a surface. This involves the synthesis of tailor-made molecules, the development and use of analytical methods to study such modified surfaces, and the use of experimental and theoretical (quantum-chemical) methods to quantitatively understand this.
This interest has recently expanded to both the (site selective) modification of protein surfaces and single polymer studies.
近期论文
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High Rates of Quinone-Alkyne Cycloaddition Reactions are Dictated by Entropic Factors
ChemRxiv
2023 | Other
DOI: 10.26434/chemrxiv-2023-2ndds
EID: 2-s2.0-85148983429
Part of ISSN: 25732293
CONTRIBUTORS: Damen, J.A.M.; Escorihuela, J.; Zuilhof, H.; van Delft, F.; Albada, B.
Bifunctional Ti4+-modified paper for selective extraction or removal of phospholipids and paper spray mass spectrometry for bioanalysis in urine and plasma
Analytica Chimica Acta
2023-10 | Journal article
DOI: 10.1016/j.aca.2023.341673
CONTRIBUTORS: Wei Luo; Teris A. van Beek; Bo Chen; Han Zuilhof; Gert IJ. Salentijn
SI-PET-RAFT in flow: improved control over polymer brush growth
Polymer Chemistry
2023 | Journal article
DOI: 10.1039/D3PY00488K
CONTRIBUTORS: Andriy R. Kuzmyn; Martijn van Galen; Barend van Lagen; Han Zuilhof
DFT Study of Imine‐Exchange Reactions in Iron(II)‐Coordinated Pincers
Chemistry – A European Journal
2023-11-02 | Journal article
DOI: 10.1002/chem.202301795
CONTRIBUTORS: Annemieke van Dam; Robin van Schendel; Satesh Gangarapu; Han Zuilhof; Maarten M. J. Smulders
Toward the Rational Design of More Efficient Mo2C Catalysts for Hydrodeoxygenation–Mechanism and Descriptor Identification
ACS Catalysis
2023-10-20 | Journal article
DOI: 10.1021/acscatal.3c03728
CONTRIBUTORS: Raghavendra Meena; Johannes Hendrik Bitter; Han Zuilhof; Guanna Li
Tunable Supramolecular Ag+-Host Interactions in Pillar[n]arene[m]quinones and Ensuing Specific Binding to 1-Alkynes
Molecules
2023-10-10 | Journal article
DOI: 10.3390/molecules28207009
CONTRIBUTORS: Yumei Zhu; Jorge Escorihuela; Haiying Wang; Andrew C.-H. Sue; Han Zuilhof
Internal hydrogen bonding of imines to control and enhance the dynamic mechanical properties of covalent adaptable networks
European Polymer Journal
2023-08 | Journal article
DOI: 10.1016/j.eurpolymj.2023.112209
CONTRIBUTORS: Sybren K. Schoustra; Vahid Asadi; Han Zuilhof; Maarten M.J. Smulders
Enantiospecific Synthesis of Aniline-Derived Sulfonimidamides
Organic Letters
2023-08-04 | Journal article
DOI: 10.1021/acs.orglett.3c02132
CONTRIBUTORS: Dong-Dong Liang; Natassa Lional; Bas Scheepmaker; Muthusamy Subramaniam; Guanna Li; Fedor M. Miloserdov; Han Zuilhof
Sulfur fluoride exchange
Nature Reviews Methods Primers
2023-08-03 | Journal article
DOI: 10.1038/s43586-023-00241-y
CONTRIBUTORS: Joshua A. Homer; Long Xu; Namitharan Kayambu; Qinheng Zheng; Eun Joung Choi; Byeong Moon Kim; K. Barry Sharpless; Han Zuilhof; Jiajia Dong; John E. Moses
High Rates of Quinone‐Alkyne Cycloaddition Reactions are Dictated by Entropic Factors
Chemistry – A European Journal
2023-07-11 | Journal article
DOI: 10.1002/chem.202300231
CONTRIBUTORS: Johannes A. M. Damen; Jorge Escorihuela; Han Zuilhof; Floris L. van Delft; Bauke Albada
Modular Design for Proteins Assembling into Antifouling Coatings: Case of Gold Surfaces
Langmuir
2023-07-11 | Journal article
DOI: 10.1021/acs.langmuir.3c00389
CONTRIBUTORS: Chuanbao Zheng; Nicolò Alvisi; Robbert Jan de Haas; Zhisen Zhang; Han Zuilhof; Renko de Vries
19 nm‐Thick Grafted‐To Polymer Brushes onto Optimized Poly(Dopamine)‐Coated Surfaces
Advanced Materials Interfaces
2023-06 | Journal article
DOI: 10.1002/admi.202202503
CONTRIBUTORS: Lucas W. Teunissen; Maarten M. J. Smulders; Han Zuilhof
Correction to “Toward Improving Triplet Energy Transfer from Tetracene to Silicon Using a Covalently Bound Tetracene Seed Layer”
The Journal of Physical Chemistry Letters
2023-06-15 | Journal article
DOI: 10.1021/acs.jpclett.3c01487
CONTRIBUTORS: Alyssa F. J. van den Boom; Silvia Ferro; María C. Gelvez-Rueda; Han Zuilhof; Bruno Ehrler
Modular and Substrate-Independent Grafting-To Procedure for Functional Polymer Coatings
Langmuir
2023-06-06 | Journal article
DOI: 10.1021/acs.langmuir.3c00280
CONTRIBUTORS: Lucas W. Teunissen; Maarten M. J. Smulders; Han Zuilhof
Toward Improving Triplet Energy Transfer from Tetracene to Silicon Using a Covalently Bound Tetracene Seed Layer
The Journal of Physical Chemistry Letters
2023-05-18 | Journal article
DOI: 10.1021/acs.jpclett.3c00589
CONTRIBUTORS: Alyssa F. J. van den Boom; Silvia Ferro; María Gelvez-Rueda; Han Zuilhof; Bruno Ehrler
Correction to “Sulfur-Phenolate Exchange as a Mild, Fast, and High-Yielding Method toward the Synthesis of Sulfonamides”
Organic Letters
2023-03-03 | Journal article
DOI: 10.1021/acs.orglett.3c00361
CONTRIBUTORS: Alyssa F. J. van den Boom; Han Zuilhof
Sulfur-Phenolate Exchange as a Mild, Fast, and High-Yielding Method toward the Synthesis of Sulfonamides
Organic Letters
2023-02-10 | Journal article
DOI: 10.1021/acs.orglett.2c04292
CONTRIBUTORS: Alyssa F. J. van den Boom; Han Zuilhof
Biointerfaces and Biopolymers
Macromolecular Bioscience
2022 | Journal article
DOI: 10.1002/mabi.202200439
EID: 2-s2.0-85141715913
Part of ISSN: 16165195 16165187
CONTRIBUTORS: Rodriguez-Emmenegger, C.; Zuilhof, H.
Calibrating catalytic DNA nanostructures for site-selective protein modification
ChemRxiv
2022 | Other
DOI: 10.26434/chemrxiv-2022-kbglv
EID: 2-s2.0-85128849464
Part of ISSN: 25732293
CONTRIBUTORS: Keijzer, J.F.; Zuilhof, H.; Albada, B.
Crown ether-modified polyelectrolytes and their interactions with cations – A QCM study
Applied Surface Science Advances
2022 | Journal article
DOI: 10.1016/j.apsadv.2022.100271
EID: 2-s2.0-85135881945
Part of ISSN: 26665239
CONTRIBUTORS: Sahin, S.; van Weeren, E.; Zuilhof, H.; de Smet, L.C.P.M.
Degradable click-reaction-based polymers as highly functional materials
Matter
2022 | Journal article
DOI: 10.1016/j.matt.2022.06.033
EID: 2-s2.0-85135534646
Part of ISSN: 25902385 25902393
CONTRIBUTORS: Subramaniam, M.; Ruggeri, F.S.; Zuilhof, H.
Enhanced monovalent over divalent cation selectivity with polyelectrolyte multilayers in membrane capacitive deionization via optimization of operational conditions
Desalination
2022 | Journal article
DOI: 10.1016/j.desal.2021.115391
EID: 2-s2.0-85122521147
Part of ISSN: 00119164
CONTRIBUTORS: Sahin, S.; Zuilhof, H.; Zornitta, R.L.; de Smet, L.C.P.M.
Recent progress in the structural study of ion channels as insecticide targets
Insect Science
2022 | Journal article
DOI: 10.1111/1744-7917.13032
EID: 2-s2.0-85132615512
Part of ISSN: 17447917 16729609
CONTRIBUTORS: Hadiatullah, H.; Zhang, Y.; Samurkas, A.; Xie, Y.; Sundarraj, R.; Zuilhof, H.; Qiao, J.; Yuchi, Z.
Ryanodine Receptor as Insecticide Target
Current Pharmaceutical Design
2022 | Journal article
DOI: 10.2174/1381612827666210902150224
EID: 2-s2.0-85122241522
Part of ISSN: 18734286 13816128
CONTRIBUTORS: Samurkas, A.; Yao, L.; Hadiatullah, H.; Ma, R.; Xie, Y.; Sundarraj, R.; Zuilhof, H.; Yuchi, Z.
Synthesis of well-defined linear–bottlebrush–linear triblock copolymer towards architecturally-tunable soft materials
Polymer Chemistry
2022 | Journal article
DOI: 10.1039/D2PY00841F
CONTRIBUTORS: Vahid Asadi; Xuecong Li; Francesco Simone Ruggeri; Han Zuilhof; Jasper van der Gucht; Thomas E. Kodger
Twisted pentagonal prisms: AgnL2 metal-organic pillars
Chem
2022 | Journal article
DOI: 10.1016/j.chempr.2022.04.001
EID: 2-s2.0-85129245455
Part of ISSN: 24519294 24519308
CONTRIBUTORS: Wan, X.; Li, S.; Tian, Y.; Xu, J.; Shen, L.-C.; Zuilhof, H.; Zhang, M.; Sue, A.C.-H.
Boronate affinity paper spray mass spectrometry for determination of elevated levels of catecholamines in urine
Analytica Chimica Acta
2022-12 | Journal article
DOI: 10.1016/j.aca.2022.340508
CONTRIBUTORS: Wei Luo; Teris A. van Beek; Bo Chen; Han Zuilhof; Gert IJ. Salentijn
Sulfur-Phenolate Exchange As a Fluorine-Free Approach to S(VI) Exchange Chemistry on Sulfonyl Moieties
Organic Letters
2022-12-02 | Journal article
DOI: 10.1021/acs.orglett.2c03421
CONTRIBUTORS: Alyssa F.J. van den Boom; Muthusamy Subramaniam; Han Zuilhof
Biointerfaces and Biopolymers
Advanced Materials Interfaces
2022-11 | Journal article
DOI: 10.1002/admi.202202252
CONTRIBUTORS: Cesar Rodriguez‐Emmenegger; Han Zuilhof
Thermoresponsive Polymer Brushes for Switchable Protein Adsorption via Dopamine‐Assisted Grafting‐To Strategy
Advanced Materials Interfaces
2022-11 | Journal article
DOI: 10.1002/admi.202201198
CONTRIBUTORS: Lucas W. Teunissen; Jelle van den Beukel; Maarten M. J. Smulders; Han Zuilhof
Antiviral Polymer Brushes by Visible-Light-Induced, Oxygen-Tolerant Covalent Surface Coating
ACS Omega
2022-11-01 | Journal article
DOI: 10.1021/acsomega.2c03214
CONTRIBUTORS: Andriy R. Kuzmyn; Lucas W. Teunissen; Michiel V. Kroese; Jet Kant; Sandra Venema; Han Zuilhof
Semiquantitative Screening of THC Analogues by Silica Gel TLC with an Ag(I) Retention Zone and Chromogenic Smartphone Detection
Analytical Chemistry
2022-10-11 | Journal article
DOI: 10.1021/acs.analchem.2c01627
CONTRIBUTORS: Si Huang; Ruiying Qiu; Zhengfa Fang; Ke Min; Teris A. van Beek; Ming Ma; Bo Chen; Han Zuilhof; Gert IJ. Salentijn
Calibrating Catalytic DNA Nanostructures for Site‐Selective Protein Modification**
Chemistry – A European Journal
2022-09-12 | Journal article
DOI: 10.1002/chem.202200895
CONTRIBUTORS: Jordi F. Keijzer; Han Zuilhof; Bauke Albada
Sulfur–Phenolate Exchange: SuFEx‐Derived Dynamic Covalent Reactions and Degradation of SuFEx Polymers
Angewandte Chemie International Edition
2022-09-05 | Journal article
DOI: 10.1002/anie.202207456
CONTRIBUTORS: Yang Chao; Akash Krishna; Muthusamy Subramaniam; Dong‐Dong Liang; Sidharam P. Pujari; Andrew C.‐H. Sue; Guanna Li; Fedor M. Miloserdov; Han Zuilhof
“Rim‐Differentiated” Pillar[6]arenes
Angewandte Chemie International Edition
2022-08 | Journal article
DOI: 10.1002/anie.202204589
CONTRIBUTORS: Yang Chao; Tushar Ulhas Thikekar; Wangjian Fang; Rong Chang; Jiong Xu; Nianfeng Ouyang; Jun Xu; Yan Gao; Minjie Guo; Han Zuilhof et al.
PUFA-Derived N-Acylethanolamide Probes Identify Peroxiredoxins and Small GTPases as Molecular Targets in LPS-Stimulated RAW264.7 Macrophages
ACS Chemical Biology
2022-08-19 | Journal article
DOI: 10.1021/acschembio.1c00355
CONTRIBUTORS: Ian-Arris de Bus; Antoine H. P. America; Norbert C. A. de Ruijter; Milena Lam; Jasper W. van de Sande; Mieke Poland; Renger F. Witkamp; Han Zuilhof; Michiel G. J. Balvers; Bauke Albada
Synthetic Strategy towards a Carbocyclic N‐Acetylneuraminic Acid
European Journal of Organic Chemistry
2022-07-21 | Journal article
DOI: 10.1002/ejoc.202200297
CONTRIBUTORS: Pieter de Saint Aulaire; Jorin Hoogenboom; Michiel T. Uiterweerd; Han Zuilhof; Tom Wennekes
Binding S(VI) to alkynes
Nature Synthesis
2022-05-30 | Journal article
DOI: 10.1038/s44160-022-00081-w
CONTRIBUTORS: Fedor Miloserdov; Han Zuilhof
Highly Specific Protein Identification by Immunoprecipitation–Mass Spectrometry Using Antifouling Microbeads
ACS Applied Materials & Interfaces
2022-05-25 | Journal article
DOI: 10.1021/acsami.1c22734
CONTRIBUTORS: Esther van Andel; Mark Roosjen; Stef van der Zanden; Stefanie C. Lange; Dolf Weijers; Maarten M. J. Smulders; Huub F. J. Savelkoul; Han Zuilhof; Edwin J. Tijhaar
Self-healing antifouling polymer brushes: Effects of degree of fluorination
Applied Surface Science
2022-03 | Journal article
DOI: 10.1016/j.apsusc.2021.152264
CONTRIBUTORS: Annemieke van Dam; Maarten M.J. Smulders; Han Zuilhof
Thermoresponsive, Pyrrolidone‐Based Antifouling Polymer Brushes
Advanced Materials Interfaces
2022-02 | Journal article
DOI: 10.1002/admi.202101717
CONTRIBUTORS: Lucas W. Teunissen; Andriy R. Kuzmyn; Francesco S. Ruggeri; Maarten M. J. Smulders; Han Zuilhof
Configurationally Chiral SuFEx‐Based Polymers
Angewandte Chemie
2022-02-14 | Journal article
DOI: 10.1002/ange.202116158
CONTRIBUTORS: Dong‐Dong Liang; Sidharam P. Pujari; Muthusamy Subramaniam; Maarten Besten; Han Zuilhof
Frontispiece: Vectorial Catalysis in Surface‐Anchored Nanometer‐Sized Metal–Organic Frameworks‐Based Microfluidic Devices
Angewandte Chemie International Edition
2022-02-14 | Journal article
DOI: 10.1002/anie.202280861
CONTRIBUTORS: Anna Lisa Semrau; Philip M. Stanley; Dominik Huber; Michael Schuster; Bauke Albada; Han Zuilhof; Mirza Cokoja; Roland A. Fischer
Vectorial Catalysis in Surface‐Anchored Nanometer‐Sized Metal–Organic Frameworks‐Based Microfluidic Devices
Angewandte Chemie International Edition
2022-02-14 | Journal article
DOI: 10.1002/anie.202115100
CONTRIBUTORS: Anna Lisa Semrau; Philip M. Stanley; Dominik Huber; Michael Schuster; Bauke Albada; Han Zuilhof; Mirza Cokoja; Roland A. Fischer
Diblock and Random Antifouling Bioactive Polymer Brushes on Gold Surfaces by Visible‐Light‐Induced Polymerization (SI‐PET‐RAFT) in Water
Advanced Materials Interfaces
2022-01 | Journal article
DOI: 10.1002/admi.202101784
CONTRIBUTORS: Andriy R. Kuzmyn; Lucas W. Teunissen; Pina Fritz; Barend van Lagen; Maarten M. J. Smulders; Han Zuilhof
Antibiotic-Like Activity of Atomic Layer Boron Nitride for Combating Resistant Bacteria
ACS Nano
2021 | Journal article
DOI: 10.1021/acsnano.1c11353
EID: 2-s2.0-85130030435
Part of ISSN: 1936086X 19360851
CONTRIBUTORS: Pan, Y.; Zheng, H.; Li, G.; Li, Y.; Jiang, J.; Chen, J.; Xie, Q.; Wu, D.; Ma, R.; Liu, X. et al.
Ionization of glycans from alkali metal salt-impregnated paper
Talanta
2021 | Journal article
DOI: 10.1016/j.talanta.2021.122674
EID: 2-s2.0-85109431926
Part of ISSN: 00399140
CONTRIBUTORS: Guo, P.; Min, K.; Luo, W.; Huang, S.; Yang, Z.; Ma, M.; Liu, S.; Fang, Z.; Chen, B.; Zuilhof, H.
Molecular control over vitrimer-like mechanics – tuneable dynamic motifs based on the Hammett equation in polyimine materials
Chemical Science
2021 | Journal article
DOI: 10.1039/D0SC05458E
CONTRIBUTORS: Sybren K. Schoustra; Joshua A. Dijksman; Han Zuilhof; Maarten M. J. Smulders
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