个人简介
Education Experience：
2001-2005 Bachelor of Science Biological Sciences Tianjin Normal University
2006-2009 M.S. Botany Tianjin Normal University
2009-2012 Ph. D. Biomolecular Engineering Tianjin University
Professional Experience：
2013- Associate Professor Tianjin University
Courses：
Bioinformatics
Laboratory Exercises in Microbiology
研究领域
Engineering and modification of Saccharomyces cerevisiae chassis for immunological
Yeast (S. cerevisiae) has served as cell factory for the production against veterinary virus, and other kinds of immunologic agents on modifying the immune response.
近期论文
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Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination
Nucleic Acids Research
2023-06-23 | Journal article
DOI: 10.1093/nar/gkad281
CONTRIBUTORS: Paula G Cerqueira; Damon Meyer; Lilin Zhang; Benjamin Mallory; Jie Liu; Becky Xu Hua Fu; Xiaoping Zhang; Wolf-Dietrich Heyer
Recombinant hemagglutinin protein and DNA-RNA-combined nucleic acid vaccines harbored by yeast elicit protective immunity against H9N2 avian influenza infection
Huixia Zhang , Ruyu Xie , Han Zhang , Ruiqi Sun , Shujun Li , Chuandao Xia , Zexing Li , Lilin Zhang , Yanyu Guo , Jinhai Huang
Poultry Science，Volume 102, Issue 6, June 2023, 102662，https://doi.org/10.1016/j.psj.2023.102662
N-Acetyltransferase 9 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Proliferation by N-Terminal Acetylation of the Structural Protein GP5
Microbiology Spectrum
2023-02-14 | Journal article
DOI: 10.1128/spectrum.02442-22
CONTRIBUTORS: Xiaoyang Li; Ruiqi Sun; Yanyu Guo; Huixia Zhang; Ruyu Xie; Xubin Fu; Lei Zhang; Lilin Zhang; Zexing Li; Jinhai Huang et al.
Oral immunization of recombinant Saccharomyces cerevisiae expressing fiber-2 of fowl adenovirus serotype 4 induces protective immunity against homologous infection
Cao Hongwei,Hua Deping,Zhang Han,Zhang Huixia,Liu Na,Feng Zhehan,Li Huliang,Zhao Baiping,Zhang Lilin,Guo Yanyu,Huang Jinhai,Zhang Lei
Page:109490 ISSN:0378-1135 2022
Container-title:Veterinary Microbiology
Oral SARS-CoV-2 Spike Protein Recombinant Yeast Candidate Prompts Specific Antibody and Gut Microbiota Reconstruction in Mice
Zhang Lilin,Yao Lan,Guo Yanyu,Li Xiaoyang,Ma Li,Sun Ruiqi,Han Xueqing,Liu Jing,Huang Jinhai
ISSN:1664-302X 2022
Container-title:Frontiers in Microbiology
PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 to Promote PRRSV Proliferation
Viruses
2022-02-18 | Journal article
DOI: 10.3390/v14020424
CONTRIBUTORS: Ruiqi Sun; Yanyu Guo; Xiaoyang Li; Ruiqiao Li; Jingxuan Shi; Zheng Tan; Lilin Zhang; Lei Zhang; Jun Han; Jinhai Huang
Complete Genome Sequence and Phylogenetic Analysis of a Goose Astrovirus Isolate in China
2022-01-14 | Preprint
DOI: 10.21203/rs.3.rs-1245798/v1
CONTRIBUTORS: ZHENG Tan; Hui Zhai; Ruqi Sun; Ruyu Xie; Zhe Sun; Lilin Zhang; Zexing Li; jinhai huang
The C/EBPβ-Dependent Induction of TFDP2 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Proliferation
Virologica Sinica
2021-12 | Journal article
DOI: 10.1007/s12250-021-00403-w
CONTRIBUTORS: Min Zhu; Xiaoyang Li; Ruiqi Sun; Peidian Shi; Aiping Cao; Lilin Zhang; Yanyu Guo; Jinhai Huang
The glycosyltransferase ST3GAL2 modulates virus proliferation and the inflammation response in porcine reproductive and respiratory syndrome virus infection
Archives of Virology
2021-10-28 | Journal article
DOI: 10.1007/s00705-021-05180-1
CONTRIBUTORS: Xiaoyang Li; Yanyu Guo; Yinna Song; Ruiqi Sun; Min Zhu; Zheng Tan; Umm E Swaiba; Lilin Zhang; Jinhai Huang
Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors
Proceedings of the National Academy of Sciences
2021-10-12 | Journal article
DOI: 10.1073/pnas.2107699118
CONTRIBUTORS: Yunjie Xiao; Hongli Chen; Haofeng Wang; Mengwen Zhang; Xia Chen; Jason M. Berk; Lilin Zhang; Yi Wei; Wenling Li; Wen Cui et al.
The superposition anti-viral activity of porcine tri-subtype interferon expressed by Saccharomyces cerevisiae
Veterinary Microbiology
2021-08 | Journal article
DOI: 10.1016/j.vetmic.2021.109150
CONTRIBUTORS: Hui Zhai; Jingxuan Shi; Ruiqi Sun; Zheng Tan; Umm E. Swaiba; Wanqing Li; Lilin Zhang; Lei Zhang; Yanyu Guo; Jinhai Huang
Porcine Immunoglobulin Fc Fused P30/P54 Protein of African Swine Fever Virus Displaying on Surface of S. cerevisiae Elicit Strong Antibody Production in Swine
Virologica Sinica
2021-04-11 | Journal article
DOI: 10.1007/s12250-020-00278-3
CONTRIBUTORS: Chen Chen; Deping Hua; Jingxuan Shi; Zheng Tan; Min Zhu; Kun Tan; Lilin Zhang; Jinhai Huang
The Glycosyltransferase ST3GAL2 Modulate the Proliferation and Inflammation Response in PRRSV Infection
2021-02-15 | Preprint
DOI: 10.21203/rs.3.rs-164471/v1
CONTRIBUTORS: Yinna Song; Yanyu Guo; Xiaoyang Li; Ruiqi Sun; Min Zhu; Zheng Tan; Umm E Swaiba; Lilin Zhang; jinhai huang
Visual Detection of Clostridium perfringens Alpha Toxin by Combining Nanometer Microspheres with Smart Phones
Microorganisms
2020-11-26 | Journal article
DOI: 10.3390/microorganisms8121865
CONTRIBUTORS: Aiping Cao; Heng Chi; Jingxuan Shi; Ruiqi Sun; Kang Du; Yinna Song; Min Zhu; Lilin Zhang; Jinhai Huang
RBM39 alters phosphorylation of c-Jun and binds to viral RNA to promote PRRSV proliferation
2020-11-14 | Other
DOI: 10.1101/2020.11.13.382531
CONTRIBUTORS: Yinna Song; Yanyu Guo; Xiaoyang Li; Ruiqi Sun; Min Zhu; Jingxuan Shi; Lilin Zhang; Jinhai Huang
The antiviral protein viperin interacts with the viral N protein to inhibit proliferation of porcine epidemic diarrhea virus
Archives of Virology
2020-10-27 | Journal article
DOI: 10.1007/s00705-020-04747-8
CONTRIBUTORS: Jiaqi Wu; Heng Chi; Yali Fu; Aiping Cao; Jingxuan Shi; Min Zhu; Lilin Zhang; Deping Hua; Jinhai Huang
Porcine FcεRI Mediates Porcine Reproductive and Respiratory Syndrome Virus Multiplication and Regulates the Inflammatory Reaction
Virologica Sinica
2018-06-14 | Journal article
DOI: 10.1007/s12250-018-0032-3
CONTRIBUTORS: Peidian Shi; Lilin Zhang; Jiashun Wang; Dong Lu; Yi Li; Jie Ren; Menglu Shen; Lei Zhang; Jinhai Huang
Immunological effects of different types of synthetic CpG oligodeoxynucleotides on porcine cells
RSC Advances
2017 | Journal article
DOI: 10.1039/C7RA04493C
CONTRIBUTORS: Ruiqiao Li; Lilin Zhang; Peidian Shi; Hui Deng; Yi Li; Jie Ren; Xubin Fu; Lei Zhang; Jinhai Huang
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