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个人简介

Education Experience: 1995-1999 Bachelor of Science Polymer materials and engineering Institution, Pol East China University of Science and Technology 2005-2008 M.S. Institute of Hematology, Biochemistry and Molecula Peking Union Medical College 2008-2013 Ph. D. Medical School, Biochemistry and Molecular Biolog Nankai University Professional Experience: 1997-2005 Lecture Peking Union Medical College/Institute of Hematology 2013- Assistant Professor Tianjin University/School of Life Sciences

研究领域

Estrogen Metabolite Prevents Hypertension. I focuses on research of estrogen metabolite inhibits proliferation of vascular smooth muscle cells (SMCs) and vascular contractility through an endothelium-dependent mechanism.

近期论文

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The solution structure of human leptin reveals a conformational plasticity important for receptor recognition Xiao Fan, Ruiqi Qin, Wensu Yuan, Jing-Song Fan, Weidong Huang, Zhi Lin Published:November 03, 2023 DOI:https://doi.org/10.1016/j.str.2023.10.009 Fan, X., Qin, R., Yuan, W. et al. Chemical shift assignments of wildtype human leptin. Biomol NMR Assign 17, 265–268 (2023). https://doi.org/10.1007/s12104-023-10153-3 Recent progress in leptin signaling from a structural perspective and its implications for diseases Fan Xiao,Yuan Wensu,Huang Weidong,Lin Zhi Page:60-75 ISSN:0300-9084 2023 Container-title:Biochimie Equilibrium between monomers and dimers of the death domain of the p75 neurotrophin receptor in solution Li Zhen,Duan Yajing,Mao Wenhui,Chen Cheng,Yuan Wensu,Jin Xinghua,Shi Shuo,Su Xun-Cheng,Ibáñez Carlos F.,Lin Zhi Page:125710 ISSN:0141-8130 2023 Container-title:International Journal of Biological Macromolecules Structural insights of the toxin-antitoxin system VPA0770-VPA0769 in Vibrio parahaemolyticus Zhang Yan,Song Xiaojie,Chen Cheng,Liu Lin,Xu Yangyang,Zhang Ning,Huang Weidong,Zheng Jun,Yuan Wensu,Tang Le,Lin Zhi Page:124755 ISSN:0141-8130 2023 Container-title:International Journal of Biological Macromolecules Artificial superstrong silkworm silk surpasses natural spider silks Wang Jingxia,Fan Tiantian,Li Xi,Hu Xiaoxia,Huang Weidong,Yuan Wensu,Lin Zhi Page:4396-4406 ISSN:2590-2385 2022 Container-title:Matter Correction: Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains Zhang Ning,Kisiswa Lilian,Ramanujan Ajeena,Li Zhen,Sim Eunice Weiling,Tian Xianbin,Yuan Wensu,Ibáñez Carlos F.,Lin Zhi Page:102583 ISSN:0021-9258 2022 Container-title:Journal of Biological Chemistry Song, X., Lin, Z. & Yuan, W. Toxin–antitoxin systems in pathogenic Vibrio species: a mini review from a structure perspective. 3 Biotech 12, 125 (2022). https://doi.org/10.1007/s13205-022-03178-3 A Structural and Functional Perspective of Death Receptor 6 Ren Xiuying,Lin Zhi,Yuan Wensu ISSN:1663-9812 2022 Container-title:Frontiers in Pharmacology 1H, 15N and 13C resonance assignments of a repetitive domain of tubuliform spidroin 2 Fan Tiantian,Zhang Yan,Fan Jing-Song,Yuan Wensu,Lin Zhi Page:475-477 ISSN:1874-2718 2021 Container-title:Biomolecular NMR Assignments Characterization and analysis of a novel diguanylate cyclase PA0847 from Pseudomonas aeruginosa PAO1 Infection and Drug Resistance 2019 | Journal article DOI: 10.2147/IDR.S194462 EID: 2-s2.0-85067574064 CONTRIBUTORS: Zhang, Y.; Guo, J.; Zhang, N.; Yuan, W.; Lin, Z.; Huang, W. Death domain of p75 neurotrophin receptor: a structural perspective on an intracellular signalling hub Biological Reviews 2019 | Journal article DOI: 10.1111/brv.12502 EID: 2-s2.0-85061591950 CONTRIBUTORS: Yuan, W.; Ibáñez, C.F.; Lin, Z. Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily Ning Zhang, Wensu Yuan, Jing-Song Fan & Zhi Lin Scientific Reports volume 7, Article number: 7073 (2017) 1H, 15N and 13C chemical shift assignments of the C-terminal domain of TRADD Biomolecular NMR Assignments 2017 | Journal article DOI: 10.1007/s12104-017-9763-6 EID: 2-s2.0-85027491353 CONTRIBUTORS: Zhang, N.; Yuan, W.; Fan, J.-S.; Lin, Z. From EST to novel spider silk gene identification for production of spidroin-based biomaterials Scientific Reports 2017 | Journal article DOI: 10.1038/s41598-017-13876-1 EID: 2-s2.0-85031818557 CONTRIBUTORS: Huang, W.; Zhang, Y.; Chen, Y.; Wang, Y.; Yuan, W.; Zhang, N.; Lam, T.J.; Gong, Z.; Yang, D.; Lin, Z.

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