个人简介
Education Experience：
1991-1996 Bachelor of Science Medical Science/ Nutrition and Food Hygiene Norman Bethune University of Medical Science, Ji-L
1996-1999 M.S. Radiation Biology Norman Bethune University of Medical Science, Ji-L
1999-2002 Ph. D. Radiation Biology Jilin Universtiy, Ji-Lin, China
2007-2011 Postdoctoral Cancer Gene Therapy Columbia University, New York, USA
Professional Experience：
1999-2001 Teaching Assistant Norman Bethune University of Medical Science, Jilin, China
2002-2004 Lecturer Jilin University, Jilin, China
2005-2010 Associate Professor Jilin University, Jilin, China
2011-2012 Research Associate Mount Sinai School of Medicine, New York USA
2013- Associate Professor Tianjin University, Tianjin, China
授课信息：
Modern Biology Techniques
Pharmacology Primer
研究领域
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Human long interspersed elements 1 (LINE-1 or L1) is the only autonomous non-LTR retroelement in humans and has been associated with genome instability, inherited genetic diseases, and the development of cancer. Certain human APOBEC3 family proteins are known to have LINE-1 restriction activity. Our group focuses on exploring the mechanisms of APOBEC3 family proteins on LINE-1 restriction. Some of A3 proteins interact with LINE-1 ORF1p to target LINE-1 ribonucleoprotein particles in an RNA-dependent manner and further Inhibit the LINE-1 reverse transcriptase activity.
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