个人简介
Education Experience：
2005-2009 Bachelor of Engineering Bioinformatics Huazhong University of Science and Technology
2009-2014 Doctor of Philosophy Structural Biology Tsinghua University
Professional Experience：
2014-2019 Postdoc University of Pennsylvania
2019- Associate professor Tianjin Univesity
研究领域
We’re interested in solving important and interesting scientific problems with structural biology and protein engineering techniques. Currently, our research has been focused on three directions:
1) Molecular mechanism underlying the regulation of vesicle trafficking.
2) Structure based semi-rational engineering of enzymes.
3)Orthogonal system in yeast cells.
近期论文
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Acetylation of SCFD1 regulates SNARE complex formation and autophagosome-lysosome fusion
Autophagy
2023-01-02 | Journal article
DOI: 10.1080/15548627.2022.2064624
CONTRIBUTORS: Hong Huang; Qinqin Ouyang; Kunrong Mei; Ting Liu; Qiming Sun; Wei Liu; Rong Liu
Engineering of triterpene metabolism and overexpression of the lignin biosynthesis gene PAL promotes ginsenoside Rg3 accumulation in ginseng plant chassis
Yao, L (Yao, Lu) ; Zhang, HY (Zhang, Huanyu) ; Liu, YR (Liu, Yirong) ; Ji, QS (Ji, Qiushuang) ; Xie, J (Xie, Jing) ; Zhang, R (Zhang, Ru) ; Huang, LQ (Huang, Luqi) ; Mei, KR (Mei, Kunrong) ; Wang, J (Wang, Juan) ; Gao, WY (Gao, Wenyuan)，Published Sep 2022 | JOURNAL OF INTEGRATIVE PLANT BIOLOGY | DOI：10.1111/jipb.13315
mTOR-mediated phosphorylation of VAMP8 and SCFD1 regulates autophagosome maturation
Nature Communications
2021-11-16 | Journal article
DOI: 10.1038/s41467-021-26824-5
CONTRIBUTORS: Hong Huang; Qinqin Ouyang; Min Zhu; Haijia Yu; Kunrong Mei; Rong Liu
A shedding soluble form of interleukin-17 receptor D exacerbates collagen-induced arthritis through facilitating TNF-α-dependent receptor clustering
Liu, SH (Liu, Sihan) ; Fu, YX (Fu, Yanxia) ; Mei, KR (Mei, Kunrong) ; Jiang, YA (Jiang, Yinan) ; Sun, XJ (Sun, Xiaojun) ; Wang, YY (Wang, Yinyin) ; Ren, FL (Ren, Fangli) ; Jiang, CS (Jiang, Congshan) ; Meng, LS (Meng, Liesu) ; Lu, SM (Lu, Shemin) ; Qin, ZH (Qin, Zhihai) ; Dong, C (Dong, Chen) ; Wang, XQ (Wang, Xinquan) ; Chang, ZJ (Chang, Zhijie) ; Yang, SG (Yang, Shigao) DOI：10.1038/s41423-020-00548-w CELLULAR & MOLECULAR IMMUNOLOGY
ULK1 phosphorylates Exo70 to suppress breast cancer metastasis
Mao, L (Mao, Liyuan) ; Zhan, YY (Zhan, Yan-yan) ; Wu, B (Wu, Bin) ; Yu, Q (Yu, Qiang) ; Xu, L (Xu, Liang) ; Hong, XT (Hong, Xiaoting) ; Zhong, LH (Zhong, Linhai) ; Mi, PY (Mi, Panying) ; Xiao, L (Xiao, Li) ; Wang, XQ (Wang, Xinquan) ; Cao, HW (Cao, Hanwei) ; Zhang, WQ (Zhang, Wenqing) ; Chen, BB (Chen, Binbin) ; Xiang, JZ (Xiang, Jingzhou) ; Mei, KR (Mei, Kunrong) ; Radhakrishnan, R (Radhakrishnan, Ravi) ; Guo, W (Guo, Wei) ; Hu, TH (Hu, Tianhui) DOI：10.1038/s41467-019-13923-7
Nature Communications
Exocytosis: A New Exocyst Movie
Mei, KR (Mei, Kunrong) ; Guo, W (Guo, Wei) DOI：10.1016/j.cub.2018.11.022 CURRENT BIOLOGY
Analysis of the Role of Sec3 in SNARE Assembly and Membrane Fusion
Mei, Kunrong ; Yue, Peng ; Guo, Wei
Published Jan 2019 |
Methods in Molecular Biology
The exocyst complex
Mei, Kunrong and Guo, Wei
Published Sep 2018 | CURRENT BIOLOGY
Cryo-EM structure of the exocyst complex
Mei, KR (Mei, Kunrong) ; Li, Y (Li, Yan) ; Wang, SX (Wang, Shaoxiao) ; Shao, GC (Shao, Guangcan) ; Wang, J (Wang, Jia) ; Ding, YH (Ding, Yuehe) ; Luo, GZ (Luo, Guangzuo) ; Yue, P (Yue, Peng) ; Liu, JJ (Liu, Jun-Jie) ; Wang, XQ (Wang, Xinquan) ; Dong, MQ (Dong, Meng-Qiu) ; Wang, HW (Wang, Hong-Wei) ; Guo, W (Guo, Wei) DOI：10.1038/s41594-017-0016-2 Nature Structural Biology
Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion
Yue, P (Yue, Peng) ; Zhang, YB (Zhang, Yubo) ; Mei, KR (Mei, Kunrong) ; Wang, SX (Wang, Shaoxiao) ; Lesigang, J (Lesigang, Johannes) ; Zhu, YY (Zhu, Yueyao) ; Dong, G (Dong, Gang) ; Guo, W (Guo, Wei) DOI：10.1038/ncomms14236 Nature Communications
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