个人简介
Education Experience：
2009-2016 Postdoctoral Genetics Harvard Medical School, U.S.A
2003-2009 Ph. D. Molecular Genetics Georgia Institude of Technology, U.S.A
1997-1999 M.S. Microbiology Hanyang University, S. Korea
Professional Experience：
2022-01-01 to present | Associate Professor (Division of Natural and Applied Sciences) | Duke Kunshan University
2016-10-01 to 2021-12-31 | Associate Professor (School of Pharmaceutical Science and Technology) | Tianjin University
2009-2016 Research fellow Harvard Medical School, U.S.A
2004-2009 Research and Teaching assistant Georgia Institute of Technology, U.S.A
1999-2003 Research scientist Hanyang University Medical School, S.Korea
1997-1998 Research and Teaching assistant Hanyang University, S.Korea
研究领域
We are interested in understanding the DNA repair mechanism in the germline. Especially, we have focused on investigating the epigenetic regulation of DNA damage response and repair. We use a microscopic size nematode C. elegans and mammalian cells to study epigenetic control of DNA repair mechanism. 1. The role of conserved Epigenetic regulators in DNA repair and damage response. 2.The role of novel and conserved gene of DNA repair and damage response.
近期论文
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Unlocking the Health Potential of Onobrychis cornuta and Veratrum lobelianum Extracts: Insights into MAPK Modulation, Germline Development, and Antitumor Properties in C. elegans: Implications for MAPK Modulation, Germline Development, and Antitumor Properties
2023-12-04 | Preprint
DOI: 10.20944/preprints202312.0154.v1
CONTRIBUTORS: Qinghao Meng; Nishit Pathak; Xiaojing Ren; Robert P. Borris; Hyun-Min Kim
Experimental Insights into the Interplay between Histone Modifiers and p53 in Regulating Gene Expression
International Journal of Molecular Sciences
2023-07 | Journal article | Author
DOI: 10.3390/ijms241311032
CONTRIBUTORS: Hyun-Min Kim; Xiaoyu Zheng; Ethan Lee
The Interplay between Histone Modifiers and p53 in Regulating Gene Expression
2023-05-30 | Preprint
DOI: 10.20944/preprints202305.2122.v1
CONTRIBUTORS: Hyun-Min Kim; Xiaoyu Zheng; Ethan Lee
A Decade of CRISPR-Cas Gnome Editing in C. elegans
International Journal of Molecular Sciences
2022-12-14 | Journal article
DOI: 10.3390/ijms232415863
CONTRIBUTORS: Hyun-Min Kim; Yebin Hong; Jiani Chen
A Decade of CRISPR-Cas Genome Editing in C. elegans
2022-11-17 | Preprint
DOI: 10.20944/preprints202211.0318.v1
CONTRIBUTORS: Hyun-Min Kim; Yebin Hong; Jiani Chen
Histone Demethylase AMX-1 Regulates Fertility in a p53/CEP-1 Dependent Manner
Ren Xiaojing,Tian Sisi,Meng Qinghao,Kim Hyun-Min
ISSN:1664-8021 2022
Container-title:Frontiers in Genetics
AMX-1 is necessary for proper fertility and lack of its expression induced sterility in a p53/CEP-1 dependent manner by modulating piwi expression in C. elegans
2022-02-25 | Preprint
DOI: 10.21203/rs.3.rs-1371441/v1
CONTRIBUTORS: Xiaojing Ren; Sisi Tian; Qinghao Meng; Hyun-Min Kim
Design of repair templates for CRISPR-Cas9-triggered homologous recombination in Caenorhabditis elegans.
CRISPR-Cas methods, volume2, Springer Nature.
2021-07-31 | Book chapter
Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage
PLOS Genetics
2021-07-30 | Journal article
DOI: 10.1371/journal.pgen.1009715
CONTRIBUTORS: Xiaojuan Zhang; Gregory P. Copenhaver; Sisi Tian; Sara E. Beese-Sims; Jingjie Chen; Nara Shin; Monica P. Colaiácovo; Hyun-Min Kim
An affordable plasmid miniprep suitable for proficient microinjection in Caenorhabditis elegans.
3 Biotech
2020-07-22 | Journal article
DOI: 10.1007/s13205-020-02346-7
PMID: 32728517
CRISPR-Cas9-Guided Genome Engineering in Caenorhabditis elegans.
Current protocols in molecular biology
2019-12-01 | Journal article
DOI: 10.1002/cpmb.106
Fanconi Anemia FANCM/FNCM-1 and FANCD2/FCD-2 Are Required for Maintaining Histone Methylation Levels and Interact with the Histone Demethylase LSD1/SPR-5 in Caenorhabditis elegans.
Genetics
2018-03-27 | Journal article
DOI: 10.1534/genetics.118.300823
Author Correction: Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis.
Nature communications
2018-08 | Journal article
DOI: 10.1038/s41467-018-05848-4
PMID: 30158624
PMC: PMC6115334
CONTRIBUTORS: Ferrandiz N; Barroso C; Telecan O; Shao N; Kim HM; Testori S; Faull P; Cutillas P; Snijders AP; Colaiácovo MP et al.
Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis.
Nature communications
2018-02-26 | Journal article
DOI: 10.1038/s41467-018-03229-5
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