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个人简介

EDUCATIONAL BACKGROUND MD (Medicine) 1996 University of Hamburg PhD (Radiology) 2005 University of Schleswig-Holstein RESEARCH EXPERIENCE Intern 1995-1997 University of Hamburg Bone Marrow Transplantation Hematology/Oncology Department Resident 1997-2001 University of Kiel Department of Radiology Research Fellow 2002-2003 Harvard Medical School Massachusetts General Hospital Center for Molecular Imaging Research Laboratory of Ralph Weissleder Research Fellow 2006-2009 Memorial Sloan Kettering Cancer Center Molecular Imaging Service Department of Radiology Laboratory of Hedvig Hricak Clinical Fellow 2006-2007 Memorial Sloan Kettering Cancer Center Body Imaging Service Department of Radiology Laboratory of Hedvig Hricak Resident 2007-2009 Memorial Sloan Kettering Cancer Center Molecular Imaging Service Department of Radiology Laboratory of Hedvig Hricak PROFESSIONAL POSITIONS & EMPLOYMENT Instructor 01/2004- 06/2006 Department of Radiology Massachusetts General Hospital Harvard Medical School Boston, MA 02114 Assistant Member 07/2009- 01/2016 Molecular Pharmacology/Chemical Biology Program Memorial Sloan Kettering Cancer Center New York, NY 10065 Assistant Attending Radiologist 07/2009- 01/2016 Department of Radiology Memorial Hospital for Cancer and Allied Diseases New York, NY 10065 Lab Head 07/2009- Present Molecular Pharmacology Program Memorial Sloan Kettering Cancer Center New York, NY 10065 Assistant Professor 07/2009- Present Gerstner Sloan Kettering Graduate School of Biomedical Sciences Memorial Sloan Kettering Cancer Center New York, NY 10065 Assistant Professor of Radiology 08/2009- Present Department of Radiology Weill Medical College of Cornell University New York, NY 10065 Assistant Professor of Pharmacology 08/2014- 04/2016 Department of Pharmacology Weill Medical College of Cornell University New York, NY 10065 Associate Member 01/2016- Present Molecular Pharmacology Program Memorial Sloan Kettering Cancer Center New York, NY 10065 Associate Attending Radiologist 01/2016- Present Department of Radiology Memorial Hospital for Cancer and Allied Diseases New York, NY 10065 Associate Professor of Pharmacology 04/2016- Present Department of Pharmacology Weill Medical College of Cornell University New York, NY 10065 Visiting Professor 11/2016- Present King’s College London WC2R 2LS, UK

研究领域

Radiologist Jan Grimm develops novel activatable molecular imaging approaches for improved detection and monitoring of prostate and other cancers.

近期论文

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Grimm J, Zeller W, Zander AR. Separation and characterization of mobilized and unmobilized peripheral blood progenitor cells by counterflow centrifugal elutriation. Exp Hematol. 1995; 23(6): 535-44. Krueger W, Stockschlader M, Sobottka I, Betker R, De Wit M, Kroger N, Grimm J, Arland M, Fiedler W,Erttmann R, Zander AR. Antimycotic therapy with liposomal amphotericin-B for patients undergoing bone marrow or peripheral blood stem cell transplantation. Leuk Lymphoma. 1997; 24(5-6): 491-9.13 Stockschlader M, Hassan HT, Krog C, Kruger W, Loliger C, Horstman M, Altnoder M, Clausen J, Grimm J,Kabisch H, Zander A. Long-term follow-up of leukemia patients after related cryopreserved allogeneic bone marrow transplantation. Br J Haematol. 1997; 96(2): 382-6. Zander AR, Berger C, Kroger N, Stockshlader M, Kruger W, Horstmann M, Grimm J, Zeller W, Kabisch H, Erttmann R, Schonrock P, Kuse R, Braumann D, Illiger HJ, Fiedler W, de Witt M, Hossfeld KD, Weh HJ. High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission. Clin Cancer Res. 1997; 3(12 Pt 2): 2671-5. Grimm J, Zeller W, Zander AR. Soluble interleukin-2 receptor serum levels after allogeneic bone marrow transplantations as a marker for GVHD. Bone Marrow Transplant. 1998; 21(1): 29-32. Muller-Hulsbeck S, Grimm J, Suwelack D, Heller M. Mechanical assistance for enhancement of in vitro effectiveness for hydrodynamic thrombectomy. Invest Radiol 1999; 34(11): 669-77. Muller-Hulsbeck S, Bathe M, Grimm J, Heller M. Enhancement of in vitro effectiveness for hydrodynamic thrombectomy devices. Simultaneous high-pressure rt-PA application. Invest Radiol. 1999; 34(8): 536-42. Muller-Hulsbeck S, Schwarzenberg H, Tschach T, Grimm J, Heller M. [In vitro comparison of a size 6F and 8F high-speed rotational catheter for mechanical thrombus fragmentation]. Rofo. 1999; 170(1):94-8. Todriia TV, Drize NI, Chertkov IL, Grimm J, Zander A. [Telomerase activity in the mouse bone marrow and subpopulations of spleen colony-forming units]. Biull Eksp Biol Med. 1999; 127(3): 311-3. Grimm J, Karger N, Lusse S, Winoto-Morbach S, Krisch B, Muller-Hulsbeck S, Heller M. Characterization of ultrasmall magnetite [correction of paramagnetic magnetite] particles as superparamagnetic contrast agents in MRI. Invest Radiol 2000; 35(9): 553-6. Jahnke T, Brossmann J, Voshage G, Hilbert C, Muller-Hulsbeck S, Grimm J, Toellner D, Heller M. [Mid-term follow-up after placement of the new balloon-expendable VIP-stent into the iliac arteries]. Rofo. 2000;172(4): 381-5. Karger N, Biederer J, Lusse S, Grimm J, Steffens J, Heller M, Gluer C. Quantitation of renal perfusion using arterial spin labeling with FAIR- UFLARE. Magn Reson Imaging 2000; 18(6): 641-7. Müller-Hülsbeck S, Grimm J, Jahnke T, Brossmann J, Hilbert C, Heller M. [First results after implantation of the new balloon-expanded Bridge-Stent into the iliac artery]. Rofo. 2000; 172(10): 836- 41. Burklein D, Lochmuller E, Kuhn V, Grimm J, Barkmann R, Muller R, Eckstein F. Correlation of thoracic and lumbar vertebral failure loads with in situ vs. ex situ dual energy X-ray absorptiometry. J Biomech. 2001;34(5): 579-87. Grimm J, Mueller-Huelsbeck S, Mueller M, Egbers HJ, Brinkmann G, Heller M. Evaluation of hydroxyapatite implants in vertebral bodies and extremities by contrast-enhanced magnetic resonance imaging. Arch Orthop Trauma Surg. 2001; 121(3): 158-61. Grimm J, Muller-Hulsbeck S, Jahnke T, Hilbert C, Brossmann J, Heller M. Randomized study to compare PTA alone versus PTA with Palmaz stent placement for femoropopliteal lesions. J Vasc Interv Radiol. 2001; 12(8):935-42. Grimm J, Muller-Hulsbeck S, Heller M. Comparison of the mechanical thrombectomy efficacy of the Amplatz thrombectomy device and the Cragg thrombolytic brush in vitro. Invest Radiol. 2001; 36(4): 204-9. Grimm J, Muller-Hulsbeck S, Blume J, Biederer J, Heller M. [Comparison of biphasic spiral CT and MnDPDPenhanced MRI in the detection and characterization of liver lesions]. Rofo. 2001; 173(3): 266-72. Jahnke T, Link J, Muller-Hulsbeck S, Grimm J, Heller M, Brossman J. Treatment of infrapopliteal occlusive disease by high-speed rotational atherectomy: initial and mid-term results. J Vasc Interv Radiol. 2001; 12(2):221-6. Muhle C, Brossmann J, Biederer J, Grimm J, Mohr A, Heller M. [Value of kinematic MRI in the evaluation of patients with exacerbated pain in cervical spine motion compared with static MRI]. Rofo. 2001; 173(2): 126- 32.

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