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教育经历 1980年9月-1985年7月,北京农业大学,专业为兽医学,获农学学士学位 1985年9月-1988年7月,北京农业大学,专业为基础兽医学,获农学硕士学位 1994年9月-1997年7月,中国农业大学,专业为农药学,获理学博士学位 工作经历 1988年7月-1991年11月,北京农业大学兽医学院,助教 1991年11月-1996年11月,北京农业大学/中国农业大学动物医学院,讲师 1996年11月-2001年11月,中国农业大学动物医学院,系主任/副教授 2001年11月-2012年3月,中国农业大学动物医学院,系主任、副院长/教授 2012年3月至今,中国农业大学动物医学院,院长/教授 获奖及荣誉 2005年北京市科学技术一等奖 “玉米赤霉醇和氯霉素等17种重要药物残留检测技术研究”(第一完成人) 2012-2013年度中华农业科技奖优秀创新团队 “动物源性食品安全检测与控制技术研究团队”(第一完成人) 2006年国家科学技术进步二等奖 “动物性食品中药物残留和化学污染物残留检测关键技术及试剂盒产业化”(第一完成人) 2012-2013年度中华农业科技奖科学研究成果一等奖 “155种重要抗菌药物及其他有害化合物残留检测关键技术与产业化”(第一完成人) 2015年度国家技术发明二等奖 “基于高性能生物识别材料的动物性产品中小分子化合物快速检测技术”(第一完成人) 2018年度中国学位与研究生教育学会研究生教育成果奖---“兽医专业学位研究生‘一优二改三培育’培养模式创新与实践”(第一完成人) 2019年度北京市自然科学一等奖 “可转移多黏菌素耐药基因mcr的发现及其传播机制研究”(第一完成人) 2020年度国家科学技术进步二等奖“食品动物新型专用药物的创制与应用”(第三完成人) 宝钢教育基金优秀教师奖(2004年) 全国优秀农业科技工作者(2005年) 北京市教育创新标兵(2006年) 教育部人才项目特聘教授(2008年) 全国优秀科技工作者(2010年) 北京市教育先锋教书育人先进个人(2011年) 全国农业科研杰出人才(2012年) 首都劳动奖章(2016年) 全国创新争先奖(2017年) 北京高校优秀共产党员(2017年) 中华农业英才(2018年) 2020年获北京市先进工作者 2020年获何梁何利基金科学与技术进步奖-农学奖 2021年获北京市优秀共产党员

研究领域

动物源性食品药物残留检测技术 细菌耐药性形成与控制

近期论文

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Meirong Song#, Ying Liu#, Tingting Li, Xiaojia Liu, Zhihui Hao, Shuangyang Ding, Pharkphoom Panichayupakaranant, Kui Zhu*, Jianzhong Shen*, Panichayupakaranant P, Zhu K, Shen J. Plant Natural Flavonoids Against Multidrug Resistant Pathogens, Advanced Science, 2021,8(15):e2100749. Yang Wang#, Chunyan Xu#, Rong Zhang#, Yiqiang Chen#, Yingbo Shen#, Fupin Hu#, Dejun Liu, Jiayue Lu, Yan Guo, Xi Xia, Junyao Jiang, Xueyang Wang, Yulin Fu, Lu Yang, Jiayi Wang, Juan Li, Chang Cai, Dandan Yin, Jie Che, Run Fan, Yongqiang Wang, Yan Qing, Yi Li, Kang Liao, Hui Chen, Mingxiang Zou, Liang Liang, Jin Tang, Zhangqi Shen, Shaolin Wang, Xiaorong Yang, Congming Wu, Shixin Xu*, Timothy R Walsh*, Jianzhong Shen*. Changes in Colistin Resistance and mcr-1 Abundance in Escherichia Coli of Animal and Human Origins Following the Ban of Colistin-Positive Additives in China: An Epidemiological Comparative Study. Lancet Infectious Disease, 2020, S1473-3099(20)30149-3. Chunyan Xu, Ziquan Lv, Yingbo Shen, Dejun Liu, Yulin Fu, Lan Zhou, Weiwen Liu, Kun Chen, Hailing Ye, Xi Xia, Junjie Xia, Yang Wang, Yuebin Ke, Jianzhong Shen, Metagenomic insights into differences in environmental resistome profiles between integrated and monoculture aquaculture farms in China. Environ Int. 2020,144:106005. Baolei Dong, Hongfang Li, Jiefang Sun, Ghulam Mujtaba Mari, Jun Ai, Diangang Han, Xuezhi Yu, Kai Wen, Jianzhong Shen*, Zhanhui Wang*, Homogeneous fluorescent immunoassay for the simultaneous detection of chloramphenicol and amantadine via the duplex FRET between carbon dots and WS2 nanosheets, Food Chemistry, 2020, 327:127107. Meirong Song#, Yuan Liu#, Xiaoyong Huang, Shuangyang Ding, Yang Wang, Jianzhong Shen*, Kui Zhu*, A Broad-Spectrum Antibiotic Adjuvant Reverses Multidrug-Resistant Gram-negative Pathogens, Nature Microbiology. 2020, 5(8):1040-1050. Yingyu Wang, Xiaowei Li, Yulin Fu, Yiqiang Chen, Yang Wang, Dongyang Ye, Chengfei Wang, Xue Hu, Lan Zhou, Jingjing Du, Jianzhong Shen*, Xi Xia*, Association of Florfenicol Residues with the Abundance of Oxazolidinone Resistance Genes in Livestock Manures, Journal of Hazard Materials. 2020, 399:123059. Tao He#, Ran Wang#, Dejun Liu#, Timothy R. Walsh, Rong Zhang, Yuan Lv, Yuebin Ke, Quanjiang Ji, Ruicheng Wei, Zhihai Liu, Yingbo Shen, Gang Wang, Lichang Sun, Lei Lei, Ziquan Lv, Yun Li, Maoda Pang, Liyuan Wang, Qiaoling Sun, Yulin Fu, Huangwei Song, Yuxin Hao, Zhangqi Shen, Shaolin Wang, Gongxiang Chen, Congming Wu, Jianzhong Shen*, Yang Wang*. Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans. Nature Microbiology, 2019, 4(9):1450-1456. Shen Yingbo#, Zhou, Hongwei#, Xu Jiao, Wang Yongqiang, Zhang Qijing, Walsh Timothy R., Shao Bing, Wu Congming, Hu Yanyan, Yang Lu, Shen Zhangqi, Wu Zuowei, Sung Qiaoling, Ou Yanran, Wang Yueling, Wang Shaolin, Wu Yongning, Cai Chang, Li Juan, Shen Jianzhong*, Zhang Rong*, Wang Yang*. Anthropogenic and environmental factors associated with high incidence of mcr-1 carriage in humans across China. Nature Microbiology. 2018, 3(9), 1054-1062. Wenbo Yu, Tingting Zhang, Mingfang Ma, Chaochao Chen, Xiao Liang, Kai Wen, Zhanhui Wang*, Jianzhong Shen*. Highly sensitive visual detection of amantadine residues in poultry at the ppb level: A colorimetric immunoassay based on a Fenton reaction and gold nanoparticles aggregation. Analytica Chimica Acta. 2018, 1027:130-136 Yang Wang#, Guobao Tian#, Rong Zhang#, Yingbo Shen#, Jonathan M. Tyrrell, Xi Huang, Hongwei Zhou, Lei Lei, Hongyu Li, Yohei Doi, Ying Fang, Hongwei Ren, Lanlan Zhong, Zhangqi Shen, Kunjiao Zeng, Shaolin Wang, Jian-Hua Liu, Congming Wu, Timothy R. Walsh*, Jianzhong Shen*. Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study. Lancet Infectious Diseases, 2017, 17(4), 390-399. Yang Wang#, Rongmin Zhang#, Jiyun Li, Zuowei Wu, Wenjuan Yin, Stefan Schwarz, Jonathan M. Tyrrell, Yongjun Zheng, Shaolin Wang, Zhangqi Shen, Zhihai Liu, Jianye Liu, Lei Lei, Mei Li, Qidi Zhang, Congming Wu, Qijing Zhang, Yongning Wu, Timothy R. Walsh* & Jianzhong Shen*. Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production. Nature Microbiology, 2017, 2, 1-7. Yiyun Liu#, Yang Wang#, Timothy R Walsh, Lingxian Yi, Rong Zhang, James Spencer, Yohei Doi, Guobao Tian, Baolei Dong, Xianhui Huang, Linfeng Yu, Danxia Gu, Hongwei Ren, Xiaojie Chen, Luchao Lv, Dandan He, Hongwei Zhou, Zisen Liang, Jianhua Liu*, Jianzhong Shen*. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infectious Diseases. 2016, 16(2), 161-168. Xuezhi Yu, Kai Wen, Zhanhui Wang, Xiya Zhang, Chenglong Li, Suxia Zhang, Jianzhong Shen*. General Bioluminescence Resonance Energy Transfer Homogeneous Immunoassay for Small Molecules Based on Quantum Dots. Analytical Chemistry, 2016, 88(7), 3512-3520 Hong Yao#, Zhangqi Shen#, Yang Wang, Fengru Deng, Dejun Liu, Gaowa Naren, Lei Dai, Chih-Chia Su, Bing Wang, Shaolin Wang, Congming Wu, Edward W. Yu, Qijing Zhang, Jianzhong Shen*. Emergence of a Potent Multidrug Efflux Pump Variant That Enhances Campylobacter Resistance to Multiple Antibiotics. MBio, 2016, 7:e01543-165. Zhanhui Wang, Xiao Liang, Kai Wen, Suxia Zhang, Chenglong Li, Jianzhong Shen. A highly sensitive and class-specific fluorescence polarisation assay for sulphonamides based on dihydropteroate synthase. Biosensors & Bioelectronics. 2015, 70, 1-4 Yang Wang#, Yuan Lv#, Jiachang Cai#, Stefan Schwarz#, Lanqing Cui, Zhidong Hu, Rong Zhang, Jun Li, Qin Zhao, Tao He, Dacheng Wang, Zheng Wang, Yingbo Shen, Yun Li, Andrea T. Fessler, Congming Wu, Hao Yu, Xuming Deng, Xi Xia, Jianzhong Shen*. A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin. Journal of Antimicrobial Chemotherapy, 2015, 70(8): 2182-2190. Wenxiao Jiang, Natalia V Beloglazova, Zhanhui Wang, Haiyang Jiang, Kai Wen, Sarah de Saeger, Pengjie Luo, Yongning Wu, Jianzhong Shen*. Development of a multiplex flow-through immunoaffinity chromatography test for the on-site screening of 14 sulfonamide and 13 quinolone residues in milk. Biosensors and Bioelectronics. 2015, 66, 124-128.

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