Manfredi, Kirk - University of Northern Iowa - Department of Chemistry and Biochemistry

研究领域

Over the past 15 years our research has been in the area of natural products isolation and structure elucidation. Most of our current work has been involved in isolating compounds from native prairie plants.

近期论文

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Boyd, M. R.; Hallock, Y. F.; Cardellina, J.H.,II; Manfredi, K.P. et. al., "Anti-HIV Michellamines from Ancistrocladus korupensis" J. Med. Chem. 1994, 1740-1745. Bringmann, G.; Gulden, P. K.; Hallock, Y.F.; Manfredi, K.P.; Cardellina, J.H.; Boyd, M.R.; Kramer, B. and Fleischhauer J. "Circular Dichroism of Michellamines: Independent Assignment of Axial Chirality by Calculated and Experimental CD Spectra" Tetrahedron 1994, 7807-7814. Hallock, Y.F.; Dai, J.R.; Bokesch, H.R.; Dillah, K.B.; Manfredi,K.P.; Cardellina, J.H. and Boyd, M.R. "Large Scale Separation of Naphthyltetrahydroisoquinoline Alkaloids from Ancistrocladus korupensis by Centrifugal Partition Chromatography" J. Chromatography A 1994, 83-88. Hallock, Y.F.; Manfredi K.P.; Cardellina J.H.; Schaffer, M.; Kunkele, Ulrike.; et.al., "Korupensamines A-D, Novel Alkaloids from Ancistrocladus korupenesis" . J. Org. Chem. 1994, 6349-6355. Manfredi, K.P., Britton,M.,Vissieche,V. and Pannell,L.K. "Three New Napthyldihydroisoquinoline Alkaloids from Ancistrocladus tectorius, J.Nat.Prod. 1996, 59(9), 854-859. Manfredi,K.P. and McGrew, L. A. "Preparation and Properties of a Stable Organic Cation: A Microscale Experiment for Organic Chemistry" J. Chem. Ed. 1996, 73 A126-126. Hollick F. Y.; Manfredi, K. P.; Dai, Jin-Rui; Cardellina, J.H.; et.al., "Michellamines D-F, New HIV-Inhibitory Dimeric Naphthylisoquinoline Alkaloids, and Korupensamine E, a New Antimalarial Monomer, from Ancistrocladus korupensis" J. Nat.Prod. 1997, 60 677-683. Kindscher, K; Manfredi, K. P.; Britton, M.; Demidova, M. and Hurlburt, B. "Testing Prairie Plants with Ethnobotanical Importance for Anti-Cancer and Anti-AIDS Compounds" J. Ethnobiology1998 18(2):229-245. Manfredi, K.P., Valurupalli, V., Demidova, M., Pannell, K.L., Kindscher,K. "Isolation of an anti-HIV diprenylated bibenzyl from Glycyrriza lepidota" Phytochemistry 58, (2001) 153-157. Barnes, Curtis C.; Smalley Mary, K.; Manfredi, Kirk P.; Kindscher, Kelly,; Loring, Hillary and Sheeley, Douglas, M. "Characterization of an Anti-tuberculosis Resin Glycoside from the Praire Medicinal Plant Ipomoea leptophylla" J. Nat. Prod. 2003, 66, 1457-1462. Miesner, S.; Frosch, H.; Kindscher, K.; Tichy, S. and Manfredi, K.P. "Benzyl Benzoate Glycosides from Oligonurion Rigidum" J.Nat. Prod. 2012, 75, 1903-1908.