杨超 - 南开大学 - 生命科学学院

个人简介

教育经历 2005.09–2009.06, 中国科学院动物研究所, 生物化学与分子生物学, 博士，导师：乔传令研究员； 2002.09–2005.06, 南开大学, 微生物学, 硕士, 导师: 宋存江教授工作经历 2015.01-至今, 南开大学, 生命科学学院, 副研究员 2011.09-2014.12, 南开大学, 生命科学学院, 助理研究员 2009.10-2011.08, 南开大学, 博士后, 合作导师: 宋存江教授

研究领域

（1）通过基因组删减构建模式微生物或工业微生物菌株的小基因组；（2）采用合成生物学方法构建生产生物材料、生物燃料和天然产物的微生物细胞工厂；（3）利用染色体无痕修饰技术构建生物安全、遗传稳定且降解谱广的多功能降解工程菌；（4）基于宏基因组学策略挖掘环境基因组中新颖的基因资源。杨超博士始终围绕“微生物代谢”这一主题，对微生物合成和分解代谢进行了系统性和创新性研究

近期论文

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Fengjie Zhao, Ting Gong, Xiangsheng Liu, Xu Fan, Rui Huang, Ting Ma, Shufang Wang,* Weixia Gao,* Chao Yang,* Morphology engineering for enhanced production of medium-chain-length polyhydroxyalkanoates in Pseudomonas mendocina NK-01. Appl. Microbiol. Biotechnol. 2019,103(4):1713-1724 Fengjie Zhao, Xiangsheng Liu, Annie Kong, Yuxin Zhao, Xu Fan, Ting Ma, Weixia Gao,* Shufang Wang,* Chao Yang,* Screening of endogenous strong promoters for enhanced production of medium-chain-length polyhydroxyalkanoates in Pseudomonas mendocina NK-01. Sci. Rep. 2019, 9:1798 Ting Gong, Xiaoqing Xu, Yulei Dang, Annie Kong, Yunbo Wu, Peixin Liang, Shufang Wang, Huilei Yu, Ping Xu, Chao Yang,* An engineered Pseudomonas putida can simultaneously degrade organophosphates, pyrethroids and carbamates. Sci. Total Environ. 2018, 628-629: 1258-1265 Yu Xia,‡Chao Yang,‡ Tong Zhang,* Microbial effects of part-stream low-frequency ultrasonic pretreatment on sludge anaerobic digestion as revealed by high-throughput sequencing-based metagenomics and metatranscriptomics. Biotechnol. Biofuels 2018, 11: 47 Chao Yang,‡ Xiaoqing Xu,‡ Yanping Liu,* Hong Jiang, Yunbo Wu, Ping Xu, Ruihua Liu,* Simultaneous hydrolysis of carbaryl and chlorpyrifos by Stenotrophomonas sp. strain YC-1 with surface-displayed carbaryl hydrolase. Sci. Rep. 2017,7: 13391 Ting Gong, Xiaoqing Xu, You Che, Ruihua Liu,* Weixia Gao, Fengjie Zhao, Huilei Yu, Jingnan Liang, Ping Xu, Cunjiang Song,* Chao Yang,* Combinatorial metabolic engineering of Pseudomonas putida KT2440 for efficient mineralization of 1,2,3-trichloropropane. Sci. Rep. 2017, 7: 7064 Chao Yang, Ying Yang, You Che, Yu Xia, Liguan Li, Wenguang Xiong, Tong Zhang,* Bioprospecting for β-lactam resistance genes using a metagenomics-guided strategy. Appl. Microbiol. Biotechnol. 2017, 101(15): 6253-6260 You Che, Peixin Liang, Ting Gong, Xiangyu Cao, Ying Zhao, Chao Yang,* Cunjiang Song,* Elucidation of major contributors involved in nitrogen removal and transcription level of nitrogen-cycling genes in activated sludge from WWTPs. Sci. Rep. 2017, 7: 44728 Weixia Gao, Fenghong Liu, Wei Zhang, Yufen Quan, Yulei Dang, Jun Feng, Yanyan Gu, Shufang Wang, Cunjiang Song,* Chao Yang,* Mutations in genes encoding antibiotic substances increase the synthesis of poly-γ-glutamic acid in Bacillus amyloliquefaciens LL3. Microbiologyopen 2017, 6(1): e00398 Ting Gong, Ruihua Liu, You Che,Xiaoqing Xu, Fengjie Zhao, Huilei Yu, Cunjiang Song,* Yanping Liu,* Chao Yang,* Engineering Pseudomonas putida KT2440 for simultaneous degradation of carbofuran and chlorpyrifos. Microbial Biotechnol. 2016, 9(6): 792-800 Chao Yang, Yu Xia, Hong Qu, An-Dong Li, Ruihua Liu, Yubo Wang, Tong Zhang,* Discovery of new cellulases from the metagenome by a metagenomics-guided strategy. Biotechnol. Biofuels 2016, 9: 138 Ting Gong, Ruihua Liu,Zhenqiang Zuo, You Che, Huilei Yu, Cunjiang Song,* Chao Yang,* Metabolic engineering of Pseudomonas putida KT2440 for complete mineralization of methyl parathion and γ-hexachlorocyclohexane.ACS Synth. Biol. 2016, 5(5): 434-442 Chao Yang,Huilei Yu,Hong Jiang,Chuanling Qiao,Ruihua Liu,* An engineered microorganism can simultaneously detoxify cadmium, chlorpyrifos and γ-hexachlorocyclohexane. J. Basic Microbiol. 2016, 56(7): 820-826 Jun Feng, Yanyan Gu, Yufen Quan, Wei Zhang, Mingfeng Cao, Weixia Gao, Cunjiang Song,* Chao Yang,* Shufang Wang,* Recruiting a new strategy to improve levan production in Bacillus amyloliquefaciens. Sci. Rep. 2015, 5: 13814 Zhenqiang Zuo, Ting Gong, You Che, Ruihua Liu,* Ping Xu, Hong Jiang, Chuanling Qiao, Cunjiang Song,* Chao Yang,* Engineering Pseudomonas putida KT2440 for simultaneous degradation of organophosphates and pyrethroids and its application in bioremediation of soil. Biodegradation 2015, 26(3): 223-233 Yuanyuan Wang, Chi Zhang, Ting Gong, Zhenqiang Zuo, Fengjie Zhao, Xu Fan, Chao Yang,* Cunjiang Song,* An upp-based markerless gene replacement method for genome reduction and metabolic pathway engineering in Pseudomonas mendocina NK-01 and Pseudomonas putida KT2440. J. Microbiol. Methods 2015, 113: 27-33 Ruihua Liu, Hong Jiang, Ping Xu, Chuanling Qiao, Qixing Zhou, Chao Yang,* Engineering chlorpyrifos-degrading Stenotrophomonas sp. YC-1 for heavy metal accumulation and enhanced chlorpyrifos degradation. Biodegradation 2014, 25(6): 903-910 Ruihua Liu, Zhenqiang Zuo, Yingming Xu, Cunjiang Song, Hong Jiang,Chuanling Qiao, Ping Xu,* Qixing Zhou,* Chao Yang,* Twin-arginine signal peptide of Bacillus subtilis YwbN can direct Tat-dependent secretion of methyl parathion hydrolase. J. Agr. Food Chem. 2014, 62(13): 2913-2918