Jamison, Timothy F. - Massachusetts Institute of Technology

个人简介

Education 1997 Ph.D. (Chemistry), Harvard University 1990 B.S. (Chemistry), University of California, Berkeley Research and Professional Experience 2015–present Department Head, MIT, Department of Chemistry 2009 –present Professor, MIT, Department of Chemistry 2006 –2009 Associate Professor, MIT, Department of Chemistry 2004 –2006 Associate Professor (without tenure), MIT, Department of Chemistry 2002 –2005 Paul M. Cook Career Development Chair 1999 –2004 Assistant Professor, MIT, Department of Chemistry 1997 –1999 Postdoctoral Fellow, Harvard University (Prof. Eric N. Jacobsen) 1991 –1997 Graduate Student, Harvard University (Prof. Stuart L. Schreiber) 1990 –1991 Fulbright Fellow, ETH Zürich, Switzerland (Prof. Steven A. Benner) 1988 –1990 Undergraduate Research, UC Berkeley (Prof. Henry Rapoport) 1988 Summer Research Assistant, Eastman Kodak, Rochester, NY 1987 Co-op Research Assistant,ICI Americas, Richmond, CA Honors, Awards, and Professional Activities 2015 –present Chemical Reviews, Associate Editor 2014 Council of Chemical Research Collaboration Award 2013 Teaching Prize for Undergraduate Education, MIT School of Science 2012 –present Fellow of the Royal Society of Chemistry 2012 Royal Society of Chemistry Merck Award 2011 Arthur C. Cope Scholar Award, American Chemical Society 2011 –present Journal of Flow Chemistry, International Advisory Board 2011 –present Advanced Synthesis and Catalysis, Academic Advisory Board 2008 –2010 Petroleum Research Fund Advisory Board 2006 JSPS Invitation Fellowship 2004 Sloan Research Fellow 2004 GlaxoSmithKline Scholar Award 2003 Amgen Young Investigator Award 2002 Paul M. Cook Career Development Chair 2002 Boehringer Ingelheim New Investigator Award 2001 National Science Foundation CAREER Award 2000 3M Innovation Award 1997 –1999 Postdoctoral Fellow, Cancer Research Fund, Damon Runyon-Walter Winchell Foundation 1991 –1994 National Science Foundation Predoctoral Fellow 1991 –1993 Certificate of Distinction in Teaching, Harvard University (3 times) 1990 –1991 Fulbright Fellow (Swiss Universities Grant) 1990 Graduated with High Honors (Chemistry), UC Berkeley 1990 Saegebarth Prize (Undergraduate Research Excellence in Chemistry) 1990 Phi Beta Kappa 1988 –1989 President's Undergraduate Fellow, UC Berkeley 1985 –1989 Chancellor's Scholar, UC Berkeley 1986 –1989 Eastman Kodak Scholar

研究领域

Research in the Jamison Group is focused on the discovery and application of new reactions and technologies for organic synthesis. Many of the transformations we target are based on common structural motifs or functional group patterns present in molecules provided to us by nature. 1.Epoxide-Opening Cascades 2.Ni-Cat C – C Bond Formation 3.Target-Oriented Synthesis 4.Continuous-Flow Chemistry

近期论文

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Bédard, A.-C.; Adamo, A.; Aroh, K. C.; Russell, M. G.; Bedermann, A. A.; Torosian, J.; Yue, B.; Jensen, K. F.; Jamison, T. F. “Reconfigurable System for Automated Optimization of Diverse Chemical Reactions,” Science 2018, 361, 1220-1225. C&EN Article. MIT News Highlight. Weber, J. M.; Longstreet, A. R.; Jamison, T. F. “Bench-Stable Nickel Precatalysts with Heck-type Activation”, Organometallics 2018, DOI: 10.1021/acs.organomet.8b00351. Gates, Z. P.; Vinogradov, A. A.; Quartararo, A. J.; Bandyopadhyay, A.; Choo, Z.-N.; Evans, E. D.; Halloran, K. H.; Mijalis, A. J.; Mong, S. K.; Simon, M. D.; Standley, E. A.; Styduhar, E. D.; Tasker, S. Z.; Touti, F.; Weber, J. M.; Wilson, J. L.; Jamison, T. F.; Pentelute, B. L. “Xenoprotein Engineering via Synthetic Libraries”, Proc. Natl. Acad. Sci. 2018, DOI: 10.1073/pnas.1722633115. Heckman, L. M.; He, Z.; Jamison, T. F. “Synthesis of Highly Substituted 2-Arylindoles via Copper-Catalyzed Coupling of Isocyanides and Arylboronic Acids”, Org. Lett. 2018, 20, 3263-3267. DOI: 10.1021/acs.orglett.8b01132. Leibfarth, F. A.; Russell, M. G.; Langley, D. M.; Seo, H.; Kelly, L. P.; Carney, D. W.; Sello, J. K.; Jamison, T. F. “Continuous-Flow Chemistry in Undergraduate Education: Sustainable Conversion of Reclaimed Vegetable Oil into Biodiesel”, J. Chem. Ed. 2018, Accepted. DOI: 10.1021/acs.jchemed.7b00719. Ziegler, R. E.; Desai, B. K.; Jee, J.-A.; Gupton, B. F.; Roper, T. D.; Jamison, T. F. “7-Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir,” Angew. Chem. Int. Ed. 2018, 57, 7181-7185. DOI: 10.1002/anie.201802256. Kelley, E. H.; Jamison, T. F. “Synthesis of the ABC Framework of Tamulamides A and B,” Bioorg. Med.Chem. 2018, Press. DOI: 10.1016/j.bmc.2018.04.046. Strieth-Kalthoff, F.; Longstreet, A. R.; Weber, J. M.; Jamison, T. F. “Bench-Stable N-Heterocyclic Carbene Nickel Precatalysts for C-C and C-N Bond-Forming Reactions,” ChemCatChem. 2018, 10, 1-6. DOI: 10.1002/cctc.201800454. Li, H.; Breen, C. P.; Seo, H.; Jamison, T. F.; Fang, Y.-Q.; Bio, M. M. “Ni-Catalyzed Electrochemical Decarboxylative C-C couplings in Batch and Continuous Flow,” Org. Lett. 2018, 20, 1338-1341. DOI: 10.1021/acs.orglett.8b00070. Zhang, P.; Weeranoppanant, N.; Thomas, D. A.; Tahara, K.; Stelzer, T.; Russell, M. G.; O’Mahony, M.; Myerson, A. S.; Lin, H.; Kelly, L. P.; Jensen, K. F.; Jamison, T. F.; Dai, C.; Cui, Y.; Briggs, N.; Beingessner, R. L.; Adamo, A. “Advaced Continuous Flow Platform for On-Demand Pharmaceutical Manufacturing,” Chem. Eur. J. 2018, 24, 2776-2784. DOI: 10.1002/chem.201706004. Katcher, M. H.; Jamison, T. F. “Studies Toward Brevisulcenal F via Convergent Strategies for Marine Ladder Polyether Synthesis,” Tetrahedron 2018, 74, 1111-1122. DOI: 10.1016/j.tet.2018.01.039.