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个人简介

中国生理学会青年工作委员会委员 中国生理学会比较生理学专业委员会委员 中国神经科学学会感觉和运动分会委员 江苏省生理科学学会副秘书长 Cerebellum & Ataxia编委

研究领域

小脑和中枢运动系统神经生物学。 包括如下两个方面: 1. 小脑的非躯体性功能,如摄食、心血管活动和情绪情感等。 2. 下丘脑这一机体自主性/内脏性活动调节高级中枢与皮层下各重要运动调控中枢(小脑、基底神经节、前庭核和脊髓)间的功能联系,特别是源自下丘脑的中枢orexin能、组胺能和CRF能等神经系统在机体躯体运动调控、重大运动疾病(共济失调、帕金森病、眩晕、运动病和猝倒症等)、以及感觉-运动整合和躯体-非躯体反应整合(包括躯体-内脏反应整合)中的作用。

近期论文

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[1] Zhang CZ, Zhuang QX, He YC, Li GY, Zhu JN* & Wang JJ*. (2013) 5-HT2A receptor-mediated excitation on cerebellar fastigial nucleus neurons and promotion of motor behaviors in rats. Pflugers Archiv - European Journal of Physioloy, doi:10.1007/s00424-013-1378-x. [2] Zhang XY, Yu L, Zhuang QX, Peng SY, Zhu JN* & Wang JJ*. (2013) Postsynaptic mechanisms underlying the excitatory action of histamine on medial vestibular nucleus neurons in rats. British Journal of Pharmacology, 170(1):156-169. [3] He YY, Zhang XY, Yung WH, Zhu JN* & Wang JJ*. (2013) Role of BDNF in central motor structures and motor diseases. Molecular Neurobiology, 48(3):783-793. [4] Zhang XY, Yu L, Zhuang QX, Zhu JN* & Wang JJ*. (2013) Central functions of the orexinergic system. Neuroscience Bulletin, 29(3):355-365. Cover Story [5] Peng SY, Zhuang QX, He YC, Zhu JN* & Wang JJ*. (2013) Histamine excites neurons of the inferior vestibular nucleus in rats by activation of H1 and H2 receptors. Neuroscience Letter, 541:87-92. [6] Zhang XY, Yu L, Zhuang QX, Zhang J, Zhu JN* & Wang JJ*. (2013) Hypothalamic histaminergic and orexinergic modulation on cerebellar and vestibular motor control. Cerebellum, 12(3):294-296. [7] Zhuang QX, Wu YH, Wu GY, Zhu JN* & Wang JJ*. (2013) Histamine excites rat superior vestibular nuclear neurons via postsynaptic H1 and H2 receptors in vitro. NeuroSignals, 21(3-4):174-183. [8] He YC, Wu GY, Li D, Tang B, Li B, Ding Y, Zhu JN* & Wang JJ*. (2012) Histamine promotes rat motor performances by activation of H2 receptors in the cerebellar fastigial nucleus. Behavioural Brain Research, 228(1):44-52. [9] Wu GY, Han XH, Zhuang QX, Zhang J, Yung WH, Chan YS, Zhu JN* & Wang JJ*. (2012) Excitatory effect of histamine on rat spinal motoneurons by activation of both H1 and H2 receptors in vitro. Journal of Neuroscience Research, 90(1):132-142. [10] Zhang J, Li B, Yu L, He YC, Li HZ, Zhu JN* & Wang JJ*. (2011) A role for orexin in central vestibular motor control. Neuron, 69(4):793-804. [11] Yu L, Zhang XY, Zhang J, Zhu JN* & Wang JJ*. (2010) Orexins excite neurons of the rat cerebellar nucleus interpositus via orexin 2 receptors in vitro. Cerebellum, 9(1):88-95. [12] Li B, Guo CL, Tang J, Zhu JN* & Wang JJ*. (2009) Cerebellar fastigial nuclear inputs and peripheral feeding signals converge on neurons in the dorsomedial hypothalamic nucleus. NeuroSignals, 17(2):132-143. [13] Zhang J, Han XH, Li HZ, Zhu JN* & Wang JJ*. (2008) Histamine excites rat lateral vestibular nuclear neurons through activation of post-synaptic H2 receptors. Neuroscience Letters, 448(1):15-19. [14] Tang B, Zhang J, Yu L, Li HZ, Zhu JN* & Wang JJ*. (2008) Excitation of histamine on neuronal activity of cerebellar fastigial nucleus in rat. Inflammation Research, 57(Suppl.1):S41-S42. [15] Zhu JN & Wang JJ*. (2008) The cerebellum in feeding control: possible function and mechanism. Cellular & Molecular Neurobiology, 28(4):469-478. [16] Zhu JN, Yung WH, Chow BKC, Chan YS & Wang JJ*. (2006) The cerebellar-hypothalamic circuits: potential pathways underlying cerebellar involvement in somatic-visceral integration. Brain Research Reviews, 52(1):93-106.

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