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个人简介

Education Background B.S. in Physics, Peking University, China (2005) Ph.D in Physics, Stanford University, USA (2011) Postdoctoral Fellow, Harvard University, USA (2014) Professor, Fudan University (2014.9 - present) Awards 2015, member of“Thousand Youth Talents Plan” 2015, Shanghai“Youth Rising Star in Science and Technology” 2010, Chinese Government Award for Outstanding Self-financed Students Abroad

研究领域

非线性光谱学和非线性光学显微成像技术。 1. 利用超快光谱技术研究材料中载流子的非平衡态动力学以及手性分子的表征 2. 利用相干拉曼成像技术研究生物和生物医学问题,包括肿瘤的非标记探测和脂类代谢等问题 3. 利用非线性光学成像手段来表征材料和器件

近期论文

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Imaging Ultrafast Dynamics of Pressure-Driven Phase Transitions in Black Phosphorus and Anomalous Coherent Phonon Softening.Wu, S.#; Chu, W.#*; Lu, Y.*; Ji, M.*, Nano Letters 2024, 24 (1), 424-432. Stimulated Raman Scattering Microscopy Enables Gleason Scoring of Prostate Core Needle Biopsy by a Convolutional Neural Network. Ao, J.#; Shao, X.#; Liu, Z.#; Liu, Q.; Xia, J.; Shi, Y.; Qi, L.; Pan, J.*; Ji, M.*, Cancer Research 2023, 83 (4), 641-651. Histological diagnosis of unprocessed breast core-needle biopsy via stimulated Raman scattering microscopy and multi-instance learning. Yang, Y.#; Liu, Z.#; Huang, J.#; Sun, X.#; Ao, J.; Zheng, B.; Chen, W.; Shao, Z.; Hu, H.*; Yang, Y.*; Ji, M.*, Theranostics 2023, 13 (4), 1342-1354. Type II collagen facilitates gouty arthritis by regulating MSU crystallisation and inflammatory cell recruitment. Xu, H.#; Zhang, B.#; Chen, Y.; Zeng, F.; Wang, W.; Chen, Z.; Cao, L.; Shi, J.; Chen, J.; Zhu, X.; Xue, Y.; He, R.*; Ji, M.*; Hua, Y.*, Annals of the Rheumatic Diseases 2023, 82(3), 416-427. Region-resolved multi-omics of the mouse eye. Xiang, H.#; Zhang, B.#; Wang, Y.; Xu, N.; Zhang, F.; Luo, R.; Ji, M.*; Ding, C.*, Cell Reports 2023, 42 (2), 112121. Significantly Accelerated Hydroxyl Radical Generation by Fe(III)–Oxalate Photochemistry in Aerosol Droplets. Wang, L.; Li, K.; Liu, Y.; Gong, K.; Liu, J.; Ao, J.; Ge, Q.; Wang, W.; Ji, M.; Zhang, L., The Journal of Physical Chemistry A 2023, 127 (1), 250-260. Imaging Low-Temperature Phases of Ice with Polarization-Resolved Hyperspectral Stimulated Raman Scattering Microscopy. Chen, Y.; Liu, Z.; Ji, M.*, The Journal of Physical Chemistry B 2023, 127 (11), 2609-2616. Stimulated Raman scattering microscopy on biological cellular machinery. Huang, J.; Ji, M., Journal of Innovative Optical Health Sciences 2023, 16 (02), 2230010. A thermodynamic model showing that information recording can drive active ion transport. Zou, X.; Song, K.; Ji, M.; Min, L.; Zhou, L.; Mao, Y.; Chen, L., Signal Transduction and Targeted Therapy 2023, 8 (1), 154. Imaging of pH distribution inside individual microdroplet by stimulated Raman microscopy. Gong, K.#; Ao, J.#; Li, K.; Liu, L.; Liu, Y.; Xu, G.; Wang, T.; Cheng, H.; Wang, Z.; Zhang, X.; Wei, H.; George, C.; Mellouki, A.; Herrmann, H.; Wang, L.; Chen, J.; Ji, M.*; Zhang, L.*; Francisco, J. S.*, Proceedings of the National Academy of Sciences 2023, 120 (20), e2219588120. Evaluating Differentiation Status of Mesenchymal Stem Cells by Label-Free Microscopy System and Machine Learning. Kong, Y.; Ao, J.; Chen, Q.; Su, W.; Zhao, Y.; Fei, Y.; Ma, J.; Ji, M.*; Mi, L.*, Cells 2023, 12 (11), 1524. 12-inch growth of uniform MoS2 monolayer for integrated circuit manufacture. Xia, Y.; Chen, X.; Wei, J.; Wang, S.; Chen, S.; Wu, S.; Ji, M.; Sun, Z.; Xu, Z.; Bao, W.; Zhou, P., Nature Materials, 2023. Photoswitchable vibrational nanoscopy with sub-100-nm optical resolution. Ao, J.; Fang, X.; Ma, L.; Liu, Z.; Wu, S.; Wu, C.; Ji, M.*, Advanced Photonics 2023, 5 (6), 066001. Fast detection and 3D imaging of nanoplastics and microplastics by stimulated Raman scattering microscopy. Ao, J.; Xu, G.; Wu, H.; Xie, L.; Liu, J.; Gong, K.; Ruan, X.; Han, J.; Li, K.; Wang, W.; Chen, T.*; Ji, M.*; Zhang, L.*, Cell Reports Physical Science 2023, 4 (10), 101623. Nondestructive Nonlinear Optical Microscopy Revealed the Blackening Mechanism of Ancient Chinese Jades. Chen, Y.; Wang, R.*; Ji, M.*, Research 2023, 6, 0266. Significantly Accelerated Photochemical Perfluorooctanoic Acid Decomposition at the Air–Water Interface of Microdroplets. Li, K.; You, W.; Wang, W.; Gong, K.; Liu, Y.; Wang, L.; Ge, Q.; Ruan, X.; Ao, J.; Ji, M.; Zhang, L., Environmental Science & Technology 2023, 57 (50), 21448-21458. Differential characterization of lumbar spine associated tissue histology with nonlinear optical microscopy. Zou, F.#; Zhang, L.#; Zou, X.#; Huang, J.; Nie, C.; Jiang, J.; Guo, C.; Wang, H.; Ma, X.*; Ji, M.*, Biomedical Optics Express 2022, 13 (1), 474-484. Generation of broadband parabolic pulses based on a pre-chirper free, core-pumped nonlinear fiber amplifier for coherent anti-Stokes Raman imaging. Yang, K.; Wu, J.; Ao, J.; Hao, Q.; Yan, M.; Huang, K.; Ji, M.; Zeng, H., Optics Express 2022, 30 (5), 7636-7646. Stimulated Raman Scattering Microscopy and Its Applications.Ao, J.; Huang, J.; Ji, M.*, Laser & Optoelectronics Progress 2022, 59 (4), 0400001. (Invited, Cover) Fiber-Enhanced Stimulated Raman Scattering and Sensitive Detection of Dilute Solutions. Guo, L.; Huang, J.; Chen, Y.; Zhang, B.; Ji, M.*, Biosensors 2022, 12 (4), 243. Ultra-Fast Synthesis of Single-Crystalline Three-Dimensional Covalent Organic Frameworks and Their Applications in Polarized Optics. Peng, L.; Sun, J.; Huang, J.; Song, C.; Wang, Q.; Wang, L.; Yan, H.; Ji, M.; Wei, D.; Liu, Y.; and Wei, D., Chemistry of Materials, 2022, 34 (7), 2886-2895. Significantly accelerated photochemical and photocatalytic reactions in microdroplets.Li, K.; Gong, K.; Liu, J.; Ohnoutek, L.; Ao, J.; Liu, Y.; Chen, X.; Xu, G.; Ruan, X.; Cheng, H.; Han, J.; Sui, G.; Ji, M.; Valev, V. K.; Zhang, L., Cell Reports Physical Science 2022, 3, 100917. Instant diagnosis of gastroscopic biopsy via deep-learned single-shot femtosecond stimulated Raman histology. Liu, Z.; Su, W.; Ao, J.; Wang, M.; Jiang, Q.; He, J.; Gao, H.; Lei, S.; Nie, J.; Yan, X.; Guo, X.; Zhou, P.*; Hu, H.*; Ji, M.*, Nature Communications 2022, 13 (1), 4050. Label-Free Delineation of Human Uveal Melanoma Infiltration With Pump–Probe Microscopy. Zhang, B.; Yao, T.; Chen, Y.; Wang, C.; Bao, Y.; Wang, Z.*; Zhao, K.*; Ji, M.*, Frontiers in Oncology 2022, 12, 891282. Composite acousto-optical modulation. Liu, R.; Ma, Y.; Ji, L.; Qiu, L.; Ji, M.; Tao, Z.; Wu, S., Optics Express 2022, 30 (15), 27780-27793. Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering. Zhang, B.; Xu, H.; Chen, J.; Zhu, X.; Xue, Y.; Yang, Y.; Ao, J.; Hua, Y.*; Ji, M.*, Theranostics 2021, 11(7), 3074-3088.(Cover story) Angle-tunable intersubband photoabsorption and enhanced photobleaching in twisted bilayer graphene. Pogna, E. A. A.; Miao, X.; von Dreifus, D.; Alencar, T. V.; Moutinho, M. V. O.; Venezuela, P.; Manzoni, C.; Ji, M.*; Cerullo, G.*; de Paula, A. M.*, Nano Research 2021. Microcalcification-Based Tumor Malignancy Evaluation in Fresh Breast Biopsies with Hyperspectral Stimulated Raman Scattering. Yang, Y.; Yang, Y.*; Liu, Z.; Guo, L.; Li, S.; Sun, X.; Shao, Z.; Ji, M.*, Analytical Chemistry, 2021, 93(15), 6223-6231. Fast tunable all-polarization-maintaining supercontinuum fiber laser for CARS microscopy. Yang, K.; Huo, L.; Ao, J.; Wang, Q.; Hao, Q.; Yan, M.; Huang, K.; Ji, M.; Zeng, H., Applied Physics Express, 2021, 14(6), 062004. Switchable stimulated Raman scattering microscopy with photochromic vibrational probes. Ao, J#; Fang, X.#; Miao, X.; Ling, J.; Kang, H.; Park, S.; Wu, C.*; Ji, M.*, Nature Communications, 2021, 12, 3089. Dichroic Photoelasticity in Black Phosphorus Revealed by Ultrafast Coherent Phonon Dynamics. Wu, S.#; Lu, Z.#; Hu, A.; Miao, X.; Wang, F.; Sun, Z.; Yan, H.; Zhang, H.*; Ji, M.*, Journal of Physical Chemistry Letters, 2021, 12(5), 5871-5878. Pump-probe Microscopy:Applications in Biomedicine and Materials Science. Wu, S.; Zhang, B.; Zheng, B.; and Ji, M.*, Acta Photonica Sinica, 2021, 50(8), 0850211-0. (Invited) Label-Free Histology and Evaluation of Human Pancreatic Cancer with Coherent Nonlinear Optical Microscopy. Zhang, L.#; Zou, X.#; Huang, J.#; Fan, J.; Sun, X.; Zhang, B.; Zheng, B.; Guo, C.; Fu, D.; Yao, L.*; Ji, M.*, Analytical Chemistry 2021, 93(46), 15550-15558. Rapid, 3D Chemical Profiling of Individual Atmospheric Aerosols with Stimulated Raman Scattering Microscopy. Ao, J., Feng, Y., Wu, S., Wang, T., Ling, J., Zhang, L.*, Ji, M.*, Small Methods 2020, 4(2), 1900600 Passively synchronized mode-locked fiber lasers for coherent anti-Stokes Raman imaging.Yang, K. W.; Shen, Y.; Ao, J. P.; Zheng, S. K.; Hao, Q.; Huang, K.; Ji, M. B.; Zeng, H. P., Optics Express 2020, 28 (9), 13721-13730. Rapid Histological Imaging Using Stimulated Raman Scattering Microscopy. Zhang, B. H.; Guo, L.; Yao, L.; Zou, X.; Ji, M. B.*, Chinese Journal of Lasers, 2020, 47 (2). Hybrid Label-Free Molecular Microscopies for Simultaneous Visualization of Changes in Cell Wall Polysaccharides of Peach at Single- and Multiple-Cell Levels during Postharvest Storage. Huang, W. N.; Nie, Y. T.; Zhu, N.; Yang, Y. F.; Zhu, C. Q.; Ji, M. B.; Wu, D.; Chen, K. S., Cells 2020, 9 (3). Rapid histology of laryngeal squamous cell carcinoma with deep-learning based stimulated Raman scattering microscopy. Zhang, L.; Wu, Y.; Zheng, B.*; Su, L.; Chen, Y.; Ma, S.; Hu, Q.; Zou, X.; Yao, L.; Yang, Y.; Chen, L.; Mao, Y.; Chen, Y.*; Ji, M.*, Theranostics 2019, 9(9), 2541-2554. (Cover story) Controlled-releasing hydrogen sulfide donor based on dual-modal iron oxide nanoparticles protects myocardial tissue from ischemia-reperfusion injury. Wang, W.; Liu, H.; Lu, Y.; Wang, X.; Zhang, B.; Cong, S.; Zhao, Y.; Ji, M.; Tao, H.; Wei, L., International Journal of Nanomedicine 2019, 14, 875-888. Label-free visualization of lignin deposition in loquats using complementary stimulated and spontaneous Raman microscopy. Zhu, N.; Yang, Y.; Ji, M.; Wu, D.*; Chen, K., Horticulture Research 2019, 6 (1), 72. Advances in Fiber Laser Sources for Coherent Raman Scattering Microscopy. Zheng, S., Yang, K., Ao, J., Ye, P., Hao, Q., Huang, K., Ji, M., and Zeng, H. Chinese Journal of Lasers2019, 46(5), 0508008. Vibrational Imaging and Quantification of Two-Dimensional Hexagonal Boron Nitride with Stimulated Raman Scattering. Ling, J., Miao, X., Sun, Y., Feng, Y., Zhang, L., Sun, Z., Ji, M.*, ACS Nano 2019, 13(12), 14033-14040 Layer-depdendent ultrafast carrier and coherent phonon dynamics in black phosphorous. Miao, X.; Zhang, G.; Wang, F.; Yan, H.*; Ji, M.*, Nano Letters 2018, 18 (5), 3053-3059. Rapid, large-scale stimulated Raman histology with strip mosaicing and dual-phase detection. Zhang, B., Sun, M., Yang, Y., Chen, L., Zou, X., Yang, T., Hua, Y., and Ji, M.*, Biomedical Optics Express 2018, 9 (6), 2604-2613. Label-free imaging of hemoglobin degradation and hemosiderin formation in brain tissues with femtosecond pump-probe microscopy. Zhang, L.; Zou, X.; Zhang, B.; Cui, L.; Zhang, J.; Mao, Y.; Chen L.*; and Ji, M.*, Theranostics 2018, 8(15), 4129-4140. Canonical Wnt signaling remodels lipid metabolism in zebrafish heptocytes following Ras oncogenic insult.Yao, Y.; Sun, S.; Wang, J.; Fei, F.; Dong, Z.; Ke, A.-W.; He, R.; Wang, L.; Zhang, L.; Ji, M.-B.; Li, Q.; Yu, M.; Shi, G.-M.; Fan, J.; Gong, Z.; Wang, X., Cancer Research 2018, 78(19), 5548-5560. Label-free imaging of amyloid plaques in Alzheimer's Disease with stimulated Raman scattering microscopy. Ji, M.#*; Arbel, M.#; Zhang, L.; Freudiger, W. C.; Hou, S. S.; Lin, D.; Yang, X.; Bacskai, J. B.*; Xie, X. S.*, Science Advances 2018, 4(11), eaat7715. Dual-phase stimulated Raman scattering microscopy for real-time two-color imaging. He, R.; Xu, Y.; Zhang, L.; Ma, S.; Wang, X.; Ye, D.; Ji, M.*, Optica 2017, 4 (1), 44-47. (Cover story) L2hgdh deficiency accumulates L-2-hydroxyglutarate with progressive leukoencephalopathy and neurodegeneration. Ma, S.; Sun, R.; Jiang, B.; Gao, J.; Deng, W.; Liu, P.; He, R.; Cui, J.; Ji, M.; Yi, W.; Yang, P.; Wu, X.; Xiong, Y.; Qiu, Z.; Ye, D.; Guan, K.-L., Molecular and Cellular Biology 2017, 37 (8), e00492-16. Stimulated Raman scattering microscopy and spectroscopy with a rapid scanning optical delay line. He, R.; Liu, Z.; Xu, Y.; Huang, W.; Ma, H.; Ji, M.*, Optics Letters 2017, 42 (4), 659-662. Label-Free, Quantitative Imaging of MoS2-Nanosheets in Live Cells with Simultaneous Stimulated Raman Scattering and Transient Absorption Microscopy. Zhang, L.#; Shen, S.#; Liu, Z.*; Ji, M.*, Advanced Biosystems 2017, 1 (4), 1700013-1700020. Towards the standardization of graphene growth through carbon depletion, refilling and nucleation. Liu, B.; Xuan, N.; Ba, K.; Miao, X.; Ji, M.; Sun, Z., Carbon 2017, 119, 350-354. Imaging laser triggered drug release from gold nanocages with transient absorption lifetime microscopy. Xu, Y.; Liu, Q; He, R.; Miao, X.; Ji, M.*, ACS Applied Materials & Interfaces 2017, 9(23), 19653-19661. Stimulated Raman scattering microscopy for rapid brain tumor histology. Yang, Y.; Chen, L.; Ji, M.*, Journal of Innovative Optical Health Sciences 2017, 11(2), 1730010-1730021. Optimizing Nonlinear Optical Visibility of Two-dimensional Materials. Miao, X.#; Xuan, N.#; Liu, Q.; Wu, W.; Liu, H.; Sun, Z.*; Ji, M.*, ACS Applied Materials & Interfaces 2017, 9(39), 34448-34455. Microsphere Assisted Super-resolution Optical Imaging of Plasmonic Interaction between Gold Nanoparticles. Hou, B.; Xie, M.; He, R.; Ji, M.; Trummer, S.; Fink, R. H.; Zhang, L., Scientific Reports 2017, 7 (1), 13789. Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging. Tian, F.; Yang, W.; Mordes, D. A.; Wang, J. Y.; Salameh, J. S.; Mok, J.; Chew, J.; Sharma, A.; Leno-Duran, E.; Suzuki-Uematsu, S.; Suzuki, N.; Han, S. S.; Lu, F. K.; Ji, M.; Zhang, R.; Liu, Y.; Strominger, J.; Shneider, N. A.; Petrucelli, L.; Xie, X. S.; Eggan, K., Nature Communications 2016, 7, 13283. Destabilization of fatty acid synthase by acetylation inhibits de novo lipogenesis and tumor cell growth. Lin, H. P.; Cheng, Z. L.; He, R. Y.; Song, L.; Tian, M. X.; Zhou, L.; B, S. G.; Liu, W.; Ji, M. B.; Ding, C.; Shi, Y. H.; Guan, K. L.; Ye, D.; Xiong, Y., Cancer Research. 2016, 76 (23), 6924-6936. Highly Efficient Destruction of Amyloid-beta Fibrils by Femtosecond Laser-Induced Nanoexplosion of Gold Nanorods. Lin, D.; He, R.; Li, S.; Xu, Y.; Wang, J.; Wei, G.; Ji, M.; Yang, X., ACS Chem Neuroscience 2016, 7 (12), 1728-1736. Laser beam controlled drug release from Ce6-gold nanorod composites in living cells: a FLIM study. Xu, Y. K.*, He, R. Y., Lin, D. D., Ji, M.*, and Chen, J. Y. Nanoscale, 2015, 7, 2433-2441. Detection of human brain tumor infiltration with quantitative stimulated Raman scattering microscopy. Ji, M.#, Lewis, S.#, Camelo-Piragua, S., Ramkissoon, S. H., Snuderl, M., Venneti, S., Fisher-Hubbard, A., Garrard, M., Fu, D., Wang, A. C., Heth, J. A., Maher, C. O., Sanai, N., Johnson, T. D., Freudiger, C. W., Sagher, O., Xie, X. S., and Orringer, D. A. Science Translational Medicine 2015, 7, 309ra163. Label-free DNA imaging in vivo with stimulated Raman scattering microscopy. Lu, F. K., Basu, S., Igras, V., Hoang, M. P., Ji, M., Fu, D., Holtom, G. R., Neel, V. A., Freudiger, C. W., Fisher, D. E., and Xie, X. S. Proc. Natl. Acad. Sci. U. S. A. 2015, 112, 11624-11629. Visualizing Brain Tumor Infiltration With Stimulated Raman Scattering Microscopy. Orringer, D.;Ji, M. B.; Lewis, S.; Camelo-Piragua, S.; Johnson, T.; Sagher, O.; Wang, A.; Maher, C.; Heth, J.; Xie, X. L., Journal of Neurosurgery 2015, 123 (2), A523-A523. Use of Stimulated Raman Scattering Microscopy for Quantitative Brain Tumor Imaging. Lewis, S.; Ji, M. B. A.; Camelo-Piragua, S.; Venneti, S.; Fisher-Hubbard, A.; Garrard, M.; Wang, A.; Heth, J.; Maher, C.; Johnson, T.; Sagher, O.; Xie, X. L.; Orringer, D. Journal of Neuropathology and Experimental Neurology 2015, 74 (6), 595-595. Real-time image guidance for brain tumor surgery through stimulated Raman scattering microscopy. Bentley, J. N., Ji, M. B., Xie, X. S. and Orringer, D. A. Expert Review of Anticancer Therapy 2014, 14 (4), 359-361. Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy. Ji, M.#, Orringer, D. A.#, Freudiger, C. W., Ramkissoon, S., Liu, X. H., Lau, D., Golby, A. J., Norton, I., Hayashi, M., Agar, N. Y. R., Young, G. S., Spino, C., Santagata, S., Camelo-Piragua, S., Ligon, K. L., Sagher, O., and Xie, X. S. Science Translational Medicine 2013, 5, 201ra119. (Cover story) Fiber optical parametric oscillator for coherent anti-Stokes Raman scattering microscopy. E. S. Lamb, S. Lefrancois, M. Ji, W. J. Wadsworth, X. Sunney Xie, F. W. Wise. Optics Letters. 2013, 38, 4154. Aqueous Mg2+ and Ca2+ Ligand Exchange Mechanisms Identified with 2DIR Spectroscopy. Sun Z., W. Zhang, M. Ji, R. Hartsock, K. Gaffney. J. Phys. Chem. B. 2013, 117,12268. Contact Ion Pair Formation between Hard Acids and Soft Bases in Aqueous Solutions Observed with 2DIR Spectroscopy. Sun Z., W. Zhang, M. Ji, R. Hartsock, K. J. Gaffney. J. Phys. Chem. B, 2013, 117,15306. Multi-color stimulated Raman scattering microscopy with a rapidly tunable optical parametric oscillator. Kong L.,# M. Ji,# Gary R. Holtom, X. Sunney Xie, et al. Optics Letters 2013, 38(2): 145-147. Site-Specific Measurement of Water Dynamics in the Substrate Pocket of Ketosteroid Isomerase Using Time-Resolved Vibrational Spectroscopy. Jhaa, S. K.#, M. Ji#, K. J. Gaffney, S. G. Boxer. J. Phys. Chem. B, 2012, 116(37): 11414-11421. Multicolor stimulated Raman scattering microscopy. Lu, F.-K., M. Ji, X. Sunney Xie, et al. Molecular Physics 2012, 1-6. Multicolored Stain-free Histopathology with Coherent Raman Imaging. Freudiger C. W., R. Pfannl, D. A. Orringer, B. G. Saar, M. Ji, X. Sunney Xie, et al. Laboratory Investigation 2012, 92, 1492-1502. Influence of Solute-Solvent Coordination on the Orientational Relaxation of Ion Assemblies in Polar Solvents. Ji, M., R. W. Hartsock, Z. Sun, K. J. Gaffney. J. Chem. Phys. 2012, 136(1): 014501. (Cover story) Dynamics of Solvent Mediated Electron Localization in Electronically Excited Hexacyanoferrate(III). Zhang, W., M. Ji, Z. Sun, K. J. Gaffney. J. Am. Chem. Soc. 2012, 134(5): 2581-2588.

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