孟歌 - 复旦大学

个人简介

教育经历 1985.9-1989.7 河南大學化学学士学位大学毕业化學專業 1989.9-1992.7 山東醫科大學药物化学硕士学位研究生毕业藥物化學專業 1999.9-2003.1 復旦大學有机化学博士学位博士研究生有機化學博士學位工作经历 2004.7-2006.7 清華大學化學系博士後博士後研究從事與雜環藥物合成相關的研究工作 2006.8-2017.6 西安交通大學醫學部藥學院教授教學與科研從事與藥物化學相關的教學與科研工作，期間共指導碩士研究生十餘名 2017.6至今复旦大学化学系研究员科研与教学工作从事与药物化学相关的科研和教学工作以及DFT相关计算研究工作。

研究领域

药物化学基于HIV-1逆转录的RNase H 变构位点的药物分子设计与构效关系研究

近期论文

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Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities .EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY .2020 ,186 Design and synthesis of a novel series of non-nucleoside HIV-1 inhibitors bearing pyrimidine and N-substituted aromatic piperazine .BIOORGANIC & MEDICINAL CHEMISTRY LETTERS .2018 ,28 (22) :3491-3495 孟歌. NaH催化合成3,4-二氢-2H-吡嗪并[2,1-b]喹唑啉-1,6-二酮及其抗肝癌细胞活性评价 .工业催化 .2020 ,28 (2) :58-63 孟歌. 取代硫脲衍生物的抗菌活性研究进展 .山东农业工程学院学报 .2020 ,37 (10) :46-50 Kaijun Jin, Yali Sang, Erick De Clercq, Christophe Pannecouque, Ge Meng*, Design and synthesis of a novel series of non-nucleoside HIV-1 inhibitors bearing pyrimidine and N-substituted aromatic piperazine. Bioorganic & Medicinal Chemistry Letters 2018, 3491-3495. Ge Meng*, Meilin Zheng, Mei Wang, et al. Design and synthesis of new potent PTP1B inhibitors with the skeleton of 2-substituted imino-3-substituted-5-heteroarylidene-1,3-thiazolidine-4-one: Part I[J]. Eur. J. Med. Chem., 2016, 122, 756-769. Ge Meng*, Meilin Zheng, Mengshu Dong,et al.Synthetic optimization of rosiglitazone and related intermediates for industrial purposes[J]. Res. Chem. Intermediat.,2016, 42(3), 2023-2033. Ge Meng, Meilin Zheng, Meng-shu Dong, et al. An environmental-friendly synthesis of 2,3- disubstituted-2-iminothiazoline-4-ones[J]. J. Heterocyclic Chem., 2016, 53(2): 588-594. Ge Meng*, Chunyan Liu, Shidong Qin, et al. An improved synthesis of sunitinib malate via a solvent-free decarboxylation process[J]. Res. Chem. Intermediat, 2015, 41, 8941-8954. Ge Meng*, Yang Liu, A-Qun Zheng, et al. Design and synthesis of a new series of modified CH-diaryl pyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors[J]. Eur. J. Med. Chem., 2014, 82, 600-611. Yang Liu, Ge Meng*, Aqun Zheng, et al. Design and synthesis of a new series of cyclopropyl amino-linking diarylpyrimidines as HIV non-nucleoside reverse transcriptase inhibitors[J]. Eur. J. Pharm. Sci., 2014, 62, 334-341. Ge Meng, Mei Wang, A-Qun Zheng, et al. Efficient one-pot synthesis of ethyl 2-substitued-4- methylthiazole-5-carboxylates[J]. Green Chem. Lett. Rev., 2014, 7(1), 46-49. Ge Meng, Mei-Lin Zheng, A-Qun Zheng, et al. The novel usage of thiourea nitrate in aryl nitration [J]. Chin. Chem. Lett. 2014, 25(1), 87-89. Ge Meng*, Mei-Lin Zheng, Meng-Shu Dong, et al. An eco-friendly preparation of 2-iminothiazolidin-4-ones derivatives[J]. Org. Prep. Proced. Int., 2012, 44(2), 184-186.