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个人简介

丁建东教授,1965年生于江苏盐城。88年本科毕业于复旦大学生命科学院生物物理专业;91年6月和95年1月分别于复旦大学材料科学系和高分子科学系获得高分子化学与物理专业硕士和博士学位;98年8月至99年8月于英国剑桥大学材料系从事博士后研究;2004年8、9月在德国海德堡大学作为高级访问学者。91年毕业留校,现为复旦大学高分子科学系教授、博士生导师、生物医用材料课题组长;复旦大学药学院兼职教授。 2004年起,担任聚合物分子工程教育部重点实验室主任;2011年11月起,担任新成立的聚合物分子工程国家重点实验室主任。 教育和工作经历 1983-1988 复旦大学生命科学学院 学士 1989-1991 复旦大学材料系 硕士 1993-1995 复旦大学高分子科学系 博士 1998-1999 英国剑桥大学材料系 博士后 1991 复旦大学 毕业留校 1998-至今 复旦大学 教授 1999-2002 国家杰出青年科学基金 项目负责人 2004-2011 聚合物分子工程教育部重点实验室 主任 2009-2013 国家重大科学研究计划"面向组织修复与替代的纳米生物材料的研究" 首席科学家 2010-2012 教育部长江学者计划 特聘教授 2016-2020 国家重点研发计划“生物材料表界面与表面改性研究” 项目负责人 2011-至今 聚合物分子工程国家重点实验室 主任

研究领域

一、组织再生材料 用于体内的、降解速率可控的生物降解高分子材料的设计和合成 生物材料的体内外降解规律 可注射性高分子水凝胶 聚乳酸和PLGA等组织工程多孔支架的制备 具有复杂人体器官外形的支架的成型加工技术 组织再生材料的表面修饰 可降解高分子与金属或陶瓷的复合材料 材料的生物活性化技术、含RGD等多肽信号分子的材料合成 组织再生材料相关的纳米技术 关节软骨再生技术 骨再生材料 用于介入治疗的心脏缺损封堵器 可降解的心血管支架 防术后组织粘连材料 内镜下切除术用的粘膜下衬垫材料 二、细胞与材料相互作用 材料表面的纳米图案化技术 材料表面的微米图案化技术 相关的连接试剂以及活性分子的合成 体细胞(含干细胞)培养和表征 生物材料的细胞毒性评价 细胞在生物材料表面黏附的微观机制 基于图案化表面的细胞/生物材料相互作用研究(细胞黏附、细胞迁移等) 材料表面的干细胞分化研究 细胞骨架与相关显微标记技术 大量细胞对于聚合物水凝胶相结构和粘弹性的影响 力学刺激所导致的细胞响应 生物材料相关的小动物实验 与细胞在材料表面行为相关的理论研究 软物质的计算机模拟(蛋白质折叠、聚合反应、大分子链动力学、水凝胶的结构与粘弹流变行为等) 三、药物缓释载体 聚酯类等用于体内的、可降解的高分子材料的合成 含PEG的嵌段共聚物类可降解高分子的分子设计与合成 热致水凝胶研究以及凝胶微粒的制备 蛋白质类药物的新型包裹技术 天然药物的新型包裹技术 降糖药物相关的材料研究和应用 抗肿瘤药物的药剂学研究和应用 相关的分子影像研究 药物与高分子材料的相互作用 新型药物缓释载体的药效评价和小动物实验

生物医用材料的应用基础研究和开发(着重研究用于体内的、可降解的合成高分子材料技术) 大分子和细胞的基础研究(着重材料/细胞相互作用的科学问题)

近期论文

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Hybrid interpenetrating network of polyester coronary stent with tunable biodegradation and mechanical properties Daokun Shi, Yahong Kang, Zailai Jiang, Xin Li, Hongjie Zhang, Qunsong Wang, Jingzhen Guo, Hongyan Jiang*, Qiyi Luo, Jiandong Ding*, Biomaterials, 299, 122411 Cheap Organocatalyst Diphenyl Phosphate for Efficient Chemical Recycling of Poly(lactic acid), Other Polyesters and Polycarbonates Wanhua Wu, Kating Wu, Xin Wang, Weihan Rao, Jiandong Ding*, and Lin Yu, Chem. Eng. J., 480, 148131 Sustained delivery of chemically modified mRNA encoding amelogenin from self-assembling hydrogels for periodontal regeneration Jie Pan, Huizhong Tian, Siming Xu, Liwei Zhang, Jiandong Ding, Huijing Wang, Lin Yu*, Wei Fu*, Xin Liu*, Composites Part B, 271 111162 Effects of serum proteins on corrosion rates and product bioabsorbability of biodegradable metals Hongjie Zhang, Xin Li, Zehua Qu, Wanqian Zhang, Qunsong Wang, Dinglingge Cao, Yaoben Wang, Xin Wang, Yang Wang, Lin Yu, Jiandong Ding*, Regen. Biomater., 11 , rbad112 Degradation-influenced/induced self-assembly of copolymers with the combinatory effects of changed molecular weight and dispersity Yiman Wei, Shuquan Cui, Lin Yu, Jiandong Ding*, Macromolecules, 56 (7), 2619–2636 An injectable and active hydrogel induces mutually enhanced mild magnetic hyperthermia and ferroptosis Xiaobin Chen, Jiayue Shi, Zhiyong Chen, Siyi Gu, Hancheng Wang, Yaoben Wang, Jiale Huang, Lin Yu*, Jiandong Ding, Biomaterials, 298, 122139 Hierarchical Helical Carbon Nanotube Fibre as a Bone Integrating ACL Replacement Liyuan Wang#, Fang Wan#, Yifan Xu#, Songlin Xie#, Tiancheng Zhao#, Fan Zhang#, Han Yang, Jiajun Zhu, Jingming Gao, Xiang Shi, Chuang Wang, Linwei Lu, Yifan Yang, Xiaoye Yu, Shiyi Chen*, Xuemei Sun*, Jiandong Ding, Peining Chen*, Chen Ding*, Fan Xu, Hongbo Yu, Huisheng Peng*, Nature Nanotechnology, https://doi.org/10.1038/s41565-023-01394-3 Versatile Hypoxic Extracellular Vesicles laden in an Injectable and Bioactive Hydrogel for Accelerated Bone Regeneration Jiajia Deng#, Xin Wang#, Weihua Zhang, Liangyan Sun, Xinxin Han, Xinqin Tong, Liming Yu*, Jiandong Ding, Lin Yu*, and Yuehua Liu*Adv. Funct. Mater., 2211664 Thermosensitive nanocomposite hydrogel composed of PVPylated poly(D,L-alanine) and laponite as an injectable and bioactive biomaterial Siyi Gu, Hancheng Wang, Yaoben Wang, Xin Wang, Xin Liu, Yang Wang, Peng Liu, Jiandong Ding, Lin Yu*,Chem. Eng. J., 466, 143128 Achieving long-acting local analgesia using an intelligent hydrogel encapsulated with drug and pH regulator Wen Guo, Dinglingge Cao, Weihan Rao, Tao Sun, Yiman Wei, Yang Wang, Lin Yu, and Jiandong Ding*, ACS Appl. Mater. Interfaces, 15, 42113-42129 Stereo coverage and overall stiffness of biomaterial arrays underly parts of topography effects on cell adhesion Qunsong Wang#, Qingsong Liu#, Jingming Gao, Junhao He, Hongjie Zhang, and Jiandong Ding*, ACS Appl. Mater. Interfaces, 15, 6142-6155 Blending strategy to modify PEEK-based orthopedic implants Zhiyong Chen, Yu Chen, Jiandong Ding, Lin Yu*,Composite B, 250, 110427 Polyetheretherketone implants with hierarchical porous structure for boosted osseointegration Zhiyong Chen, Yu Chen, Yang Wang, JiaJia Deng, Xin Wang, Qingqing Wang, Yuehua Liu, Jiandong Ding, Lin Yu*,Biomater. Res., 27, article number 61 Single-cell micropatterning by non-fouling hydrogels Wengang Liu, Tingshuan Chen, Jiandong Ding*, Methods in Molecular Biology, 2689, 65-70 Biaxial stretching of polytetrafluoroethylene in industrial scale to fabricate medical ePTFE membrane with node-fibril microstructure Gang Wang, Yusheng Feng, Caiyun Gao, Xu Zhang, Qunsong Wang, Jie Zhang, Hongjie Zhang, Yongqiang Wu, Xin Li, Lin Wang, Ye Fu, Xiaoye Yu, Deyuan Zhang, Jianxiong Liu, Jiandong Ding*, Regen. Biomater., 10, rbad056 Establishment of coverage-mass equation to quantify the corrosion inhomogeneity and examination of medium effects on iron corrosion Xin Li, Jiandong Ding*,Regen. Biomater., 10, rbad007 Quantitatively relating magnetic resonance T1 and T2 to glycosaminoglycan and collagen concentrations mediated by penetrated contrast agents and biomacromolecule-bound water Jingming Gao, Xian Xu*, Xiaoye Yu, Ye Fu, Hongjie Zhang, Siyi Gu, Dinglingge Cao, Quanyi Guo, Liming Xu, Jiandong Ding*,Regen. Biomater., 10, rbad035 Stride strategy to enable a quasi-ergodic search of reaction pathways demonstrated by ring-opening polymerization of cyclic esters Weihan Rao, Lin Yu, Jiandong Ding*,Chinese J. Polym. Sci., 41, 745–759 A Biosurfactant-containing TSD Strategy to Modify Bovine Pericardial Bioprosthetic Valves for Anticalcification Caiyun Gao, Gang Wang, Lin Wang, Qunsong Wang, Hancheng Wang, Lin Yu, Jianxiong Liu, Jiandong Ding*,Chinese J. Polym. Sci., 41, 51–66 Unified Therapeutic-Prophylactic Vaccine Demonstrated with a Postoperative Filler Gel to Prevent Tumor Recurrence and Metastasis Dinglingge Cao, Wen Guo, Caiyun Cai, Jingyu Tang, Weihan Rao, Yang Wang, Yaoben Wang, Lin Yu, Jiandong Ding*, Adv. Funct. Mater., 2206084 Sustained Release of Nitric Oxide and Cascade Generation of Reactive Nitrogen/Oxygen Species via an Injectable Hydrogel for Tumor Synergistic Therapy Yaoben Wang, Xiaowei Yang, Xiaobin Chen, Xin Wang, Yang Wang, Hancheng Wang, Zhiyong Chen, Dinglingge Cao, Lin Yu*, Jiandong Ding, Adv. Funct. Mater., 202206554 Design and Aligner-assisted Fast Fabrication of a Microfluidic Platform for Quasi-3D Cell Studies on an Elastic Polymer Yingning He, Yue Yu, Yuqian Yang, Yexin Gu, Tianjiao Mao, Yang Shen, Qiong Liu, Ruili Liu, Jiandong Ding*, Bioactive Materials, 15, 288-304 Imaging moiety-directed co-assembly for biodegradation control with synchronous four-modal biotracking Qingsong Liu, Ye Fu, Bin Wu, Jingyu Tang, Yaoben Wang, Yanping Wu, Man Zhang, Shen Shen, Yang Shen, Caiyun Gao, Jiandong Ding*, Liangliang Zhu*, Biomaterials, 287, art No. 121665 (pages 1-10) Biomaterial-related Cell Microenvironment in Tissue Engineering and Regenerative Medicine Jingming Gao, Xiaoye Yu, Xinlei Wang, Yingning He, Jiandong Ding*, Engineering, 13(6), 31-45 Intelligent Paper-Free Sprayable Skin Mask Based on an In Situ Formed Janus Hydrogel of an Environmentally Friendly Polymer Caiyun Cai, Jingyu Tang, Yi Zhang, Weihan Rao, Dinglingge Cao, Wen Guo, Lin Yu, Jiandong Ding*, Adv. Healthcare Mater., 11, 202102654 (pages 1-16) A biodegradable metal-polymer composite stent safe and effective on physiological and serum-containing biomimetic conditions Hongjie Zhang, Wanqian Zhang, Hong Qiu, Gui Zhang, Xin Li, Haiping Qi, Jingzhen Guo, Jie Qian, Xiaoli Shi, Xian Gao, Daokun Shi, Deyuan Zhang*, Runlin Gao*, Jiandong Ding*, Adv. Healthcare Mater., 11, (22), 2201740(pages 1-16) RGD nanoarrays with nanospacing gradient selectively induce orientation and directed migration of endothelial and smooth muscle cells Junhao He, Runjia Shen, Qiong Liu, Shuang Zheng, Xinlei Wang, Jingming Gao, Qunsong Wang, Jiale Huang, and Jiandong Ding*, ACS Appl. Mater. Interfaces , 14(33), 37436-37446 A facile composite strategy to prepare a biodegradable polymer based radiopaque raw material for “visualizable” biomedical implants Qunsong Wang, Xiaoye Yu, Xianmiao Chen, Jingming Gao, Daokun Shi, Yang Shen, Jingyu Tang, Junhao He, Anning Li, Lin Yu, and Jiandong Ding*, ACS Appl. Mater. Interfaces, 14(21), 24197–24212 3D-printed Porous Scaffolds of Hydrogels Modified with TGF-β1 Binding Peptide to Promote in Vivo Cartilage Regeneration and Animal Gait Restoration Xiaoquan Ding#, Jingming Gao#, Xiaoye Yu, Jiayue Shi, Jun Chen, Lin Yu, Shiyi Chen, and Jiandong Ding*, ACS Appl. Mater. Interfaces, 14(14), 15982 15995 Critical adhesion areas of cells on micro-nanopatterns Shuang Zheng, Qiong Liu, Junhao He, Xinlei Wang, Kai Ye, Xuan Wang, Ce Yan, Peng Liu, and Jiandong Ding*, Nano Res., 15(2), 1623-1635 An injectable hemostatic PEG-based hydrogel with on-demand dissolution features for emergency care Jiayue Shi, Danni Wang, Hancheng Wang, Xiaowei Yang, Siyi Gu, Yaoben Wang, Zhiyong Chen, Jingming Gao, Lin Yu*, Jiandong Ding. Acta Biomaterialia, 145, 106-121 Coordination Strategy to Achieve Instant Dissolution of a Biomedical Polymer in Water via Manual Shaking Jingyu Tang, Caiyun Cai, Dinglingge Cao, Weihan Rao, Wen Guo, Lin Yu, and Jiandong Ding*, Biomater. Sci. Recent Advances in Regenerative Biomaterials Dinglingge Cao, Jiandong Ding*,Regen. Biomater., 9, rbac098 Is polydopamine beneficial for cells on the modified surface Yue Yu, Xiuli Wang, Yi Zhu, Yingning He, Hongrui Xue, Jiandong Ding*, Regen. Biomater.,9, rbac078(pages 1-14) Research and clinical translation of three-tier stent-graft of expanded polytetrafluoroethylene for interventional treatment of aortic dissection Gang Wang, Caiyun Gao, Benhao Xiao, Jie Zhang, Xunyuan Jiang, Qunsong Wang, Jingzhen Guo, Deyuan Zhang, Jianxiong Liu, Yuehui Xie*, Chang Shu*, Jiandong Ding*, Regen. Biomater., 9, rbac049 “Invisible” orthodontics by polymeric “clear” aligners molded on 3D-printed personalized dental models Xiaoye Yu, Guanghui Li, Yikan Zheng, Jingming Gao, Ye Fu, Qunsong Wang, Xiaogang Pan*, Lei Huang*, Jiandong Ding*, Regen. Biomater., 9, rbac007 (pages 1-12) Long-term Delivery of Etanercept Mediated via a Thermosensitive Hydrogel for Efficient Inhibition of Wear Debris-induced Inflammatory Osteolysis Kewen Lei#, Yang Wang#,, Xiaochun Peng*, Lin Yu*, Jiandong Ding, J. Polym. Sci. An Intelligent Transdermal Formulation of ALA-Loaded Copolymer Thermogel with Spontaneous Asymmetry by Using Temperature-Induced Sol-Gel Transition and Gel-Sol(Suspension) Transition on Different Sides Dinglingge Cao#, Xi Chen#, Feng Cao, Wen Guo, Jingyu Tang, Caiyun Cai, Shuquan Cui, Xiaowei Yang, Lin Yu, Yong Su, Jiandong Ding*, Adv. Funct. Mater., 31(22), art No. 2100349 (pages 1-12) Surface modification to enhance cell migration on biomaterials and its combination with 3D structural design of occluders to improve interventional treatment of heart diseases Yang Shen, Wanqian Zhang, Yumei Xie, Anning Li, Xiuli Wang, Xianmiao Chen, Qingsong Liu, Qunsong Wang, Gui Zhang, Qiong Liu, Jianxiong Liu, Deyuan Zhang*, Zhiwei Zhang*, Jiandong Ding*, Biomaterials, 279, art. No. 121208 (pages 1-16) Biodegradable polymeric occluder for closure of atrial septal defect with interventional treatment of cardiovascular disease Boning Li#, Zhaofeng Xie#, Qunsong Wang#, Xianmiao Chen#, Qingsong Liu, Wei Wang, Yang Shen, Xiangdong Liu, Anning Li, Yifan Li, Gui Zhang, Jianxiong Liu, Deyuan Zhang*, Cong Liu*, Shushui Wang*, Yumei Xie*, Zhiwei Zhang*, and Jiandong Ding*, Biomaterials, 274, art No. 120851 (pages 1-15) Injectable and thermosensitive hydrogels mediating a universal macromolecular contrast agent with radiopacity for noninvasive imaging of deep tissues Xiaohui Wu, Xin Wang, Xiaobin Chen, Xiaowei Yang, Qian Ma, Guohua Xu, Lin Yu*, Jiandong Ding, Bioactive Materials, 6(12), 4717-4728 In vivo degradation and endothelialization of an iron bioresorbable scaffold Wenjiao Lin, Hongjie Zhang, Wanqian Zhang, Haiping Qi, Gui Zhang, Jie Qian, Xin Li, Li Qin, Haifeng Li, Xiang Wang, Hong Qiu, Xiaoli Shi, Wei Zheng*, Deyuan Zhang*, Runlin Gao*, Jiandong Ding*, Bioactive Materials, 6(4), 1028-1039 Decisive Influence of Hydrophobic Side Chains of Polyesters on Thermoinduced Gelation of Triblock Copolymer Aqueous Solutions Kaiting Wu, Xiaobin Chen, Siyi Gu, Shuquan Cui, Xiaowei Yang, Lin Yu*, Jiandong Ding, Macromolecules, 54 (16), 7421–7433 Cell-free Bilayered Porous Scaffolds for Osteochondral Regeneration Fabricated by Continuous 3D-Printing Using Nascent Physical Hydrogel as Ink Jingming Gao#, Xiaoquan Ding#, Xiaoye Yu, Xiaobin Chen, Xingyu Zhang, Shuquan Cui, Jiayue Shi, Jun Chen, Lin Yu, Shiyi Chen*, Jiandong Ding*, Adv. Healthcare Mater., 10, art No. 2001404 (pages 1-13) NIR Light-Triggered Quantitative Pulsed Drug Release Yang Yang, Kaiqi Long, Yiqun Wang, Lei Li, Jiayue Shi, Jican Liu, Lingxi Kong, Lin Yu, Jiandong Ding, Zhili Huang,* Weiping Wang,* and Changyou Zhan*, Adv. Healthcare Mater., 10, art No. 2102362 (pages 1-10) Enlargement, Reduction and Even Reversal of Relative Migration Speeds of Endothelial and Smooth Muscle Cells on Biomaterials Simply by Adjusting RGD Nanospacing Junhao He#, Qiong Liu#, Shuang Zheng, Runjia Shen, Xinlei Wang, Jingming Gao, Qunsong Wang, Jiale Huang, and Jiandong Ding*, ACS Appl. Mater. Interfaces, 13(36), 42344-42356 Injectable Thermogel Generated by the “Block Blend” Strategy as a Biomaterial for Endoscopic Submucosal Dissection Shuquan Cui, Yiman Wei, Qiao Bian, Yan Zhu, Xiaobin Chen, Yaping Zhuang, Mingyan Cai, Jingyu Tang, Lin Yu, and Jiandong Ding*, ACS Appl. Mater. Interfaces, 13(17), 19778–19792 Critical frequency and critical stretching rate for reorientation of cells on a cyclically stretched polymer in a microfluidic chip Tianjiao Mao, Yingning He, Yexin Gu, Yuqian Yang, Yue Yu, Xinlei Wang, and Jiandong Ding*, ACS Appl. Mater. Interfaces, 13(12), 13934 13948 Exploration of possible cell chirality using material techniques of surface patterning Xiang Yao, Xinlei Wang, Jiandong Ding*. Acta Biomaterialia, 126, 92-108 PEG-based thermosensitive and biodegradable hydrogels Jiayue Shi, Lin Yu*, Jiandong Ding. Acta Biomaterialia, 128, 42-59 Biological sealing and integration of fibrinogen-modified titanium alloy with soft and hard tissues in a rat model Xiuli Wang#, Xing Lei#, Yue Yu, Sheng Miao, Jingyu Tang, Ye Fu, Kai Ye, Yang Shen, Jiayue Shi, Hao Wu, Yi Zhu, Lin Yu, Guoxian Pei, Long Bi*, and Jiandong Ding*, Biomater. Sci., 9(15), 5192 – 5208 An oxygen-enriched thermosensitive hydrogel for the relief of hypoxic tumor microenvironment and enhancement of radi therapy Xiaowei Yang, Yaoben Wang, Tianjiao Mao, Yang Wang, Ruili Liu, Lin Yu*, and Jiandong Ding, Biomater. Sci., 9(22), 7471–7482 Magnetic resonance imaging for non-invasive clinical evaluation of normal and regenerated cartilage Xian Xu#, *, Jingming Gao#, Shuyun Liu, Liang Chen, Min Chen, Xiaoye Yu, Ning Ma, Jun Zhang, Xiaobin Chen, Lisen Zhong, Lin Yu, Liming Xu*, Quanyi Guo*, and Jiandong Ding*, Regen. Biomater., 8(5), art No. rbab038 (pages 1-13) Coordination insertion mechanism of ring-opening polymerization of lactide catalyzed by stannous octoate Weihan Rao, Caiyun Cai, Jingyu Tang, Yiman Wei, Caiyun Gao, Lin Yu, Jiandong Ding*, Chinese J. Chem., 39, 1965-1974 (2021) 两亲性共聚物热致水凝胶 王耀本,俞麟*,丁建东. 科学通报(2021) Progress of amphiphilic copolymers thermogels Yaoben Wang, Lin Yu*, Jiandong Ding. Chinese Science Bulletin (2021) Cell migration regulated by RGD nanospacing and enhanced under moderate cell adhesion on biomaterials Qiong Liu#, Shuang Zheng#, Kai Ye, Junhao He, Yang Shen, Shuquan Cui, Jiale Huang, Yexin Gu, and Jiandong Ding*, Biomaterials, 263, art. No. 120327 (2020) Strategy of “block blends” to generate polymeric thermogels versus that of one-component block copolymer Shuquan Cui, Lin Yu, Jiandong Ding*, Macromolecules, 53, 11051 - 11064 (2020) Synergism among polydispersed amphiphilic block copolymers leading to spontaneous physical hydrogelation upon heating Shuquan Cui, Liang Chen, Lin Yu, Jiandong Ding*, Macromolecules, 53, 7726 - 7739 (2020) A simplified yet enhanced and versatile microfluidic platform for cyclic cell stretching on an elastic polymer Yingning He, Tianjiao Mao, Yexin Gu, Yuqian Yang, Jiandong Ding*, Biofabrication, 12, art. No. 045032 (2020) Visualizing the in vivo evolution of an injectable and thermosensitive hydrogel using tri-modal bioimaging Xiaobin Chen, Jiulong Zhang, Kaiting Wu, Xiaohui Wu, Jingyu Tang, Shuquan Cui, Dinglingge Cao, Ruili Liu, Chen Peng*, Lin Yu*, and Jiandong Ding, Small Methods, 4, art. No. 202000310 (2020) Sustained release of lipophilic gemcitabine from an injectable polymeric hydrogel for synergistically enhancing tumor chemoradiotherapy Xiaowei Yang, Xiaobin Chen, Yaobeng Wang, Guohua Xu, Lin Yu*, and Jiandong Ding, Chem. Eng. J., 396, art. No. 125320 (2020) Long-term efficacy of biodegradable metal-polymer composite stents after the first and the second implantations into porcine coronary arteries Xin Li#, Wanqian Zhang#, Wengjiao Lin, Hong Qiu, Yongli Qi, Xun Ma, Haiping Qi, Yao He, Hongjie Zhang, Jie Qian, Gui Zhang, Runlin Gao*, Deyuan Zhang*, and Jiandong Ding*, ACS Appl. Mater. Interfaces, 12(13), 15703-15715 (2020) Effects of microstripe geometry on guided cell migration Xiang Yao, Jiandong Ding*, ACS Appl. Mater. Interfaces, 12(25), 27971–27983 (2020) Matrix-metalloproteinase-responsive gene delivery surface for enhanced in situ endothelialization Lingchuang Bai, Jing Zhao, Meiyu Wang, Yakai Feng*, Jiandong Ding, ACS Appl. Mater. Interfaces, 12: 40121-40132 (2020) Chromosomal repositioning and gene regulation of cells on a micropillar array Ruili Liu, Jiandong Ding*, ACS Appl. Mater. Interfaces, 12, 35799 35812 (2020) An excitation-dependent ratiometric dual-emission strategy for the large-scale enhancement of fluorescent tint control Dongxiao Zheng, Man Zhang, Xiuli Wang, Bin Wu, Pei Zhao, Bingbing Yue, Xiaoyong Jia, Jiandong Ding, Qi Zou*, and Liangliang Zhu*, Nanoscale, 12(24), 12773-12778 (2020) Fixed-point “blasting” triggered by the second near-infrared light for augmented interventional photothermal therapy Yongbin Cao#, Boshu Ouyang#, Xiaowei Yang, Qin Jiang, Lin Yu*, Shun Shen*, Jiandong Ding, and Wuli Yang*, Biomater. Sci., 8, 2955-2965 (2020) An injectable thermosensitive hydrogel loaded with an ancient natural drug colchicine for myocardial repair after infarction Yu Chen#, Jiayue Shi#, Yaping Zhang, Jiajun Miao, Zhe Zhao, Xian Jin, Liang Liu, Di Wang, Lin Yu*, Chengxing Shen*, Jiandong Ding, J. Mater. Chem. B, 8, 980-992 (2020) Synthesis of PCL-PEG-PCL triblock copolymer via organocatalytic ring-opening polymerization and its application as an injectable hydrogel — an interdisciplinary learning trial Kaiting Wu, Lin Yu*, Jiandong Ding, J. Chem. Edu., 97, 4158-4165 (2020) Thermogelling of amphiphilic block copolymers in water: ABA type versus AB or BAB type Shuquan Cui, Lin Yu, Jiandong Ding*, Macromolecules, 52, 3697-3715 (2019) (2019 SCI Impact factor: 5.918) Critical areas of proliferation of single cells on micropatterned surfaces and corresponding cell type dependence Xiang Yao, Ruili Liu, Xiangyu Liang, Jiandong Ding*, ACS Appl. Mater. Interfaces, 11(17), 15366-15380 (2019) Mechanism of acceleration of iron corrosion by a polylactide coating Yongli Qi, Xin Li, Yao He, Deyuan Zhang, Jiandong Ding*, ACS Appl. Mater. Interfaces, 11(1), 202-218 (2019) Sustained release strategy designed for lixisenatide delivery to synchronously treat diabetes and associated complications Yaping Zhuang, Xiaowei Yang, Yamin Li, Yipei Chen, Xiaochun Peng, Lin Yu*, and Jiandong Ding, ACS Appl. Mater. Interfaces, 11, 29604-29618 (2019) Injectable hydrogels for the sustained delivery of a HER2-targeted antibody for preventing local relapse of HER2 breast cancer after breast-conserving surgery Xiaobin Chen#, Maoli Wang#, Xiaowei Yang, Yaoben Wang, Lin Yu*, Jian Sun*, and Jiandong Ding, Theranostics, 9(21):6080-6098 (2019) Structural mechanics of 3D-printed poly(lactic acid) scaffolds with tetragonal, hexagonal and wheel-like designs Xiangyu Liang, Jingming Gao, Weike Xu, Xiuli Wang, Yang Shen, Jingyu Tang, Shuquan Cui, Xiaowei Yang, Qingsong Liu, Lin Yu, Jiandong Ding*, Biofabrication, 11(3), art No. 035009(pages 1-22) (2019) TBX6 compound inheritance leads to congenital vertebral malformations in humans and mice Nan Yang#, Nan Wu#, Ling Zhang#, Yanxue Zhao, Jiaqi Liu, Xiangyu Liang, Xiaojun Ren, Weiyu Li, Weisheng Chen, Shuangshuang Dong, Sen Zhao, Jiachen Lin, Hang Xiang, Huadan Xue, Lu Chen, Hao Sun, Jianguo Zhang, Jiangang Shi, Shuyang Zhang, Daru Lu, Xiaohui Wu, Li Jin, Jiandong Ding, Guixing Qiu, Zhihong Wu*, James R. Lupski*, Feng Zhang*, Human Molecular Genetics, 28(4), 539-547 (2019) Injectable PEG/polyester themogel: a new liquid embolization agent for temporary vascular interventional therapy Hantao Yang#, Kewen Lei#, Feng Zhou, Xiaowei Yang, Qingzhu An, Wei Zhu*, Lin Yu*, Jiandong Ding, Mater Sci Eng C Mater. Biol. Appl., 102, 606-615 (2019) Polydopamine-mediated covalent functionalization of collagen on titanium alloy to promote biocompatibility with soft tissues Yi Zhu#, Dandan Liu#, Xiuli Wang, Yao He, Wenjie Luan*, Fazhi Qi*, Jiandong Ding*, J. Mater. Chem. B, 7(12): 2019-2031 (2019) Proliferation of Cells with Severe Nuclear Deformation on a Micropillar Array Ruili Liu, Xiang Yao, Xiangnan Liu, and Jiandong Ding*, Langmuir, 35(1), 284-299 (2019) Cell type and nuclear size dependence of the nuclear deformation of cells on a micropillar array Ruili Liu, Qiong Liu, Zhen Pan, Xiangnan Liu, and Jiandong Ding*, Langmuir, 35(23), 7469-7477 (2019) Restoration of osteochondral defects by implanting bilayered poly(lactide-co-glycolide) porous scaffolds in rabbit joints for 12 and 24 weeks Pingguo Duan#, Zhen Pan#, Lu Cao, Jingming Gao, Haoqun Yao, Xiangnan Liu, Runsheng Guo, Xiangyu Liang, Jian Dong*, Jiandong Ding*, J. Orthopaedic Translation, 19, 68-80 (2019) Accelerated Cutaneous Wound Healing using an Injectable Teicoplanin-loaded PLGA-PEG-PLGA Thermogel Dressing Weike Xu, Jingyu Tang, Zhang Yuan, Caiyun Cai, Xiaobin Chen, Shuquan Cui, Peng Liu, Lin Yu*, Kaiyong Cai, Jiandong Ding, Chinese J. Polym. Sci., 37(6), 548-559 (2019) Endoscopic ultrasonography-guided poly (lactic acid-co-glycolic acid)-poly (ethylene glycol)-poly (lactic acid-co-glycolic acid) thermogel tunnel creation for natural orifice transluminal endoscopic surgery in porcine model Xiaotian Sun, Lin Yu, Jianbin Zhu, Shengzhou Zu; Jiandong Ding, Yan Liu*, J. Cancer Res. Therapeutics, 15(2): 415-419 (2019) 可X射线显影的新型碘代聚碳酸酯的设计与合成 马前, 吴晓慧, 俞麟*, 丁建东, 高等学校化学学报, 40: 2233-2240 (2019) Design and synthesis of novel iodinated polycrabonates with inherent X-ray opacity Qian Ma, Xiaohui Wu, Lin Yu*, Jiandong Ding, Chem. J. Chinese Univ., 40, 2233-2240 (2019) (in Chinese) 突破手套箱依赖的α-氨基酸N-羧基环内酸酐(NCA)快速开环聚合 丁建东*,功能高分子学报, 32(2): 120-122 (2019) Glovebox free and rapid ring-opening polymerization of α-Amino acid N-carboxyanhydrides in open-vessels Jiandong Ding*, J. Funct. Polym., 32(2): 120-122 (2019) (in Chinese) 治疗Ⅱ型糖尿病的GLP-1受体激动剂及其高分子递送系统的研究进展 庄亚平,杨孝伟,俞麟*,丁建东,功能高分子学报, 32(2): 126-139 (2019) Progress of GLP-1 receptor agonists and their polymeric delivery systems for the treatment of typeⅡdiabetes Yaping Zhuang, Xiaowei Yang, Lin Yu*, Jiandong Ding, J. Funct. Polym., 32(2): 126-139 (2019) (in Chinese) Degradation rate affords a dynamic cue to regulate stem cells beyond varied matrix stiffness Yuanmeng Peng, Qiongjie Liu, Tianlei He, Kai Ye, Xiang Yao, Jiandong Ding*, Biomaterials, 178, 467-480 (2018) Semi-bald micelles and corresponding percolated micelle networks of thermogels Shuquan Cui, Lin Yu, Jiandong Ding*, Macromolecules, 51, 6405 6420 (2018) Precisely controlling dimerization and trimerization in topochemical reaction templated by biomacromolecules Xiaoyong Jia, Mingjie Zhu, Qiao Bian, Bingbing Yue, Yaping Zhuang, Bin Wu, Lin Yu, Jiandong Ding, Junji Zhang, Liangliang Zhu*, Macromolecules, 51(20): 8038-8045 (2018) Thermogel loaded with low-dose paclitaxel as a facile coating to alleviate periprosthetic fibrous capsule formation Jiabin Luan, Zheng Zhang, Wenjia Shen, Yipei Chen, Lin Yu*, Jian Sun*, Jiandong Ding, ACS Appl. Mater. Interfaces, 10, 30235 30246 (2018) Strategy of metal-polymer composite stent to accelerate biodegradation of iron-based biomaterials Yongli Qi, Haiping Qi, Yao He, Wenjiao Lin, Peize Li, Li Qin, Yiwen Hu, Liping Chen, Qingsong Liu, Hongtao Sun, Qiong Liu, Gui Zhang, Shuquan Cui, Jun Hu, Lin Yu, Deyuan Zhang*, Jiandong Ding*, ACS Appl. Mater. Interfaces, 10, 182 192 (2018) Enzymatically cross-linked hydrogels based on a linear poly(ethylene glycol) analogue for controlled protein release and 3D cell culture Danni Wang, Qiong Liu, Xiaowei Yang, Lin Yu*, Jiandong Ding, J. Mater. Chem. B,: 6, 6067-6079 (2018) Bilayered PLGA/PLGA-HAp composite scaffold for osteochondral tissue engineering and tissue regeneration Xiangyu Liang#, Pingguo Duan#, Jingming Gao, Runsheng Guo, Zehua Qu, Xiaofeng Li, Yao He, Haoqun Yao, Jiandong Ding*, ACS Biomater. Sci. Eng., 4, 3506 3521 (2018) Design and preparation of quasi-spherical salt particles as water-soluble porogens to fabricate hydrophobic porous scaffolds for tissue engineering and tissue regeneration Xiangyu Liang, Yongli Qi, Zhen Pan, Yao He, Xiangnan Liu, Shuquan Cui, Jiandong Ding*, Mater. Chem. Front., 2, 1539-1553 (2018) A composite strategy to fabricate high-performance biodegradable stents for tissue regeneration Jiandong Ding*, Science China Materials, 61(8), 1132-1134 (2018) Left-right symmetry or asymmetry of cells on stripe-like micropatterned material surfaces Yiwen Hu, Xiang Yao, Qiong Liu, Yi Wang, Ruili Liu, Shuquan Cui, Jiandong Ding*, Chinese J. Chem., 36, 605-611 (2018) 基于适度两亲性嵌段共聚物的可注射性热致水凝胶 崔书铨,俞麟,丁建东*,高分子学报, (8), 997-1015 (2018) Injectable Thermogels Based on Block Copolymers of Appropriate Amphiphilicity Shuquan Cui, Lin Yu, Jiandong Ding*, Acta Polym. Sin., (8), 997-1015 (2018) (in Chinese)

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