陈新 - 复旦大学 - 高分子科学系

个人简介

教育工作经历 1986-1990 复旦大学高分子学士 1990-1993 复旦大学高分子硕士 1993-1996 复旦大学高分子博士 1996-2001 复旦大学讲师 1999-1999 美国布鲁克黑文国家实验室访问科学家 2000-2001 英国牛津大学研究院 2001-2008 复旦大学副教授 2008至今复旦大学教授主要荣誉与奖励上海市科学技术奖自然科学奖一等奖（第二完成人，2011）上海高校优秀青年教师（2008）‍ 教育部新世纪优秀人才（2006）教育部提名国家科学技术奖自然科学奖一等奖（第二完成人，2004）

研究领域

生理活性蛋白质的结构表征以及与材料性能的关系动物吐丝机理的研究和人工丝纤维的仿生纺制以天然高分子为基质的各类功能材料的设计、制备和应用‍ 先进红外光谱技术（同步辐射红外光谱，远红外光谱，红外光谱成像）在高分子材料中的应用

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Chen, Q. Y.; Liu, Y.; Gu, K.; Yao, J. R.; Shao, Z. Z.; Chen, X. Silk-based electrochemical sensor for the detection of glucose in sweat. Biomacromolecules 2022, 23 (9), 3928–3935. Wen, H. J.; Chen, X. Y.; Wang, Y.; Yao, J. R.; Chen, X.; Ling, S. J.; Shao, Z. Z. Proteinic artificial skin with molecularly encoded coloration. ACS Appl Mater Interfaces 2022, 14 (34), 39322-39331. Lu, M. Q.; Sun, L. Y.; Yao, J. R.; Zhao, B. J.; Liu, Y. H.; Shao, Z. Z.; Chen, X. Protein-inorganic hybrid porous scaffolds for bone tissue engineering. J Mater Chem B 2022, 10 (34), 6546-6556. Wen, H. J.; Yao, J. R.; Chen, X.; Ling, S. J.; Shao, Z. Z. Silk-derived peptide nanospirals assembled by self-propelled worm-like filaments. Nano Research 2022, DOI: 10.1007/s12274-022-4671-1. Xie, J. Y.; Gu, K.; Zhao, Y.; Yao, J. R.; Chen, X.; Shao, Z. Z. Enhancement of the mechanical properties of poly(lactic acid)/ epoxidized soybean oil blends by the addition of 3-aminophenylboronic acid. ACS Omega 2022, 7 (21), 17841–17848. Chen, L.; Sun, L. Y.; Yao, J. R.; Zhao, B. J.; Shao, Z. Z.; Chen, X. Robust silk protein hydrogels made by a facile one-step method and their multiple applications. ACS Appl Bio Mater 2022, 5 (6), 3086-3094. Lu, M. Q.; Wu, M.; Huang, Y. F.; Yao, J. R.; Shao, Z. Z.; Chen, X. Animal protein-plant protein composite nanospheres for dual-drug loading and synergistic cancer therapy. J Mater Chem B 2022, 10 (20), 3798-3807. Chen, Q. Y.; Tang, H.; Liu, J. L.; Wang, R. R.; Sun, J.; Yao, J. R.; Shao, Z. Z.; Chen, X. Silk-based pressure/temperature sensing bimodal ionotronic skin with stimulus discriminability and low temperature workability. Chem Eng J 2021, 422. Zhao, B. H.; Chen, Q. Y.; Da, G. H.; Yao, J. R.; Shao, Z. Z.; Chen, X. A highly stretchable and anti-freezing silk-based conductive hydrogel for application as a self-adhesive and transparent ionotronic skin. J Mater Chem C 2021, 9 (28), 8955-8965. Liu, Y.; Wang, W.; Gu, K.; Yao, J.; Shao, Z.; Chen, X. Poly(vinyl alcohol) Hydrogels with Integrated Toughness, Conductivity, and Freezing Tolerance Based on Ionic Liquid/Water Binary Solvent Systems. ACS Appl Mater Interfaces 2021, 13 (24), 29008-29020. Wu, M.; Han, Z. Y.; Liu, W.; Yao, J. R.; Zhao, B. J.; Shao, Z. Z.; Chen, X. Silk-based hybrid microfibrous mats as guided bone regeneration membranes. J Mater Chem B 2021, 9 (8), 2025-2032. Wu, K.; Zhao, Y.; Li, J. Q.; Yao, J. R.; Chen, X.; Shao, Z. Z. Crystallization, Mechanical, and Antimicrobial Properties of Diallyl Cyanuric Derivative-Grafted Polypropylene. Acs Omega 2021, 6 (19), 12794-12800. Duan, Y.; Chen, X.; Shao, Z. Z. Comparison of Native and Regenerated Antheraea Pernyi Silk Fibroin. Mater Sci-Medzg 2021, 27 (1), 57-62. Wang, W. Q.; Liu, Y. Z.; Wang, S. Q.; Fu, X. M.; Zhao, T. C.; Chen, X.; Shao, Z. Z. Physically Cross-Linked Silk Fibroin-Based Tough Hydrogel Electrolyte with Exceptional Water Retention and Freezing Tolerance. Acs Appl Mater Inter 2020, 12 (22), 25353-25362. Hu, L.; Chen, Q.; Yao, J.; Shao, Z.; Chen, X. Structural Changes in Spider Dragline Silk after Repeated Supercontraction-Stretching Processes. Biomacromolecules 2020, 21, 12, 5306–5314. Wu, K.; Li, J.; Chen, X.; Yao, J.; Shao, Z. Synthesis of novel multi-hydroxyl N-halamine precursors based on barbituric acid and their applications in antibacterial poly(ethylene terephthalate) (PET) materials. J Mater Chem B 2020, 8 (37), 8695-8701. Zhao, Y.; Zhao, B.; Wei, B.; Wei, Y.; Yao, J.; Zhang, H.; Chen, X.; Shao, Z. Enhanced compatibility between poly(lactic acid) and poly (butylene adipate-co-terephthalate) by incorporation of N-halamine epoxy precursor. Int J Biol Macromol 2020, 165 (Pt A), 460-471. Gong, D. F.; Lin, Q. R.; Shao, Z. Z.; Chen, X.; Yang, Y. H. Preparing 3D-printable silk fibroin hydrogels with robustness by a two-step crosslinking method. Rsc Advances 2020, 10 (45), 27225-27234. Liu, J. L.; Chen, Q. Y.; Liu, Q.; Zhao, B. H.; Ling, S. J.; Yao, J. R.; Shao, Z. Z.; Chen, X. Intelligent Silk Fibroin Ionotronic Skin for Temperature Sensing. Advanced Materials Technologies 2020, 5 (7). Wu, M.; Liu, W.; Yao, J.; Shao, Z.; Chen, X. Silk microfibrous mats with long-lasting antimicrobial function. Journal of Materials Science & Technology 2020, DOI: 10.1016/j.jmst.2020.02.060. Wei, Y.; Yao, J.; Shao, Z.; Chen, X. Water-Resistant Zein-Based Adhesives. ACS Sustainable Chemistry & Engineering 2020, 8 (20), 7668-7679 DOI: 10.1021/acssuschemeng.0c01179. Wang, H.; Dong, Q.; Yao, J.; Shao, Z.; Ma, J.; Chen, X. Colorless Silk/Copper Sulfide Hybrid Fiber and Fabric with Spontaneous Heating Property under Sunlight. Biomacromolecules 2020, 21 (4), 1596-1603 DOI: 10.1021/acs.biomac.0c00170. Hu, L.; Han, Y.; Ling, S.; Huang, Y.; Yao, J.; Shao, Z.; Chen, X. Direct Observation of Native Silk Fibroin Conformation in Silk Gland of Bombyx mori Silkworm. ACS Biomaterials Science & Engineering 2020, 6 (4), 1874-1879 DOI: 10.1021/acsbiomaterials.9b01586. Dong, Q.; Cai, J.; Wang, H.; Chen, S.; Liu, Y.; Yao, J.; Shao, Z.; Chen, X. Artificial ligament made from silk protein/Laponite hybrid fibers. Acta Biomater 2020, 106, 102-113 DOI: 10.1016/j.actbio.2020.01.045. Zhao, Y.; Wei, B.; Wu, M.; Zhang, H.; Yao, J.; Chen, X.; Shao, Z. Preparation and characterization of antibacterial poly(lactic acid) nanocomposites with N-halamine modified silica. Int J Biol Macromol 2020, 155, 1468-1477 DOI: 10.1016/j.ijbiomac.2019.11.125. Dong, Q.; Fang, G.; Huang, Y.; Hu, L.; Yao, J.; Shao, Z.; Ling, S.; Chen, X. Effect of stress on the molecular structure and mechanical properties of supercontracted spider dragline silks. J Mater Chem B 2020, 8 (1), 168-176 DOI: 10.1039/c9tb02032b. Wu, M.; Li, Z.; Yao, J.; Shao, Z.; Chen, X. Pea Protein/Gold Nanocluster/Indocyanine Green Ternary Hybrid for Near-Infrared Fluorescence/Computed Tomography Dual-Modal Imaging and Synergistic Photodynamic/Photothermal Therapy. ACS Biomaterials Science & Engineering 2019, 5 (9), 4799-4807 DOI: 10.1021/acsbiomaterials.9b00794. Fu, C.; Wang, Y.; Guan, J.; Chen, X.; Vollrath, F.; Shao, Z. Cryogenic toughness of natural silk and a proposed structure–function relationship. Materials Chemistry Frontiers 2019, 3 (11), 2507-2513 DOI: 10.1039/c9qm00282k. Dong, T.; Mi, R.; Wu, M.; Zhong, N.; Zhao, X.; Chen, X.; Shao, Z. The regenerated silk fibroin hydrogel with designed architecture bioprinted by its microhydrogel. Journal of Materials Chemistry B 2019, 7 (27), 4328-4337 DOI: 10.1039/c9tb00783k. Cao, H.; Duan, Y.; Lin, Q.; Yang, Y.; Gong, Z.; Zhong, Y.; Chen, X.; Shao, Z. Dual-loaded, long-term sustained drug releasing and thixotropic hydrogel for localized chemotherapy of cancer. Biomater Sci 2019, 7 (7), 2975-2985 DOI: 10.1039/c9bm00540d. Wei, Y.; Hu, L.; Yao, J.; Shao, Z.; Chen, X. Facile Dissolution of Zein Using a Common Solvent Dimethyl Sulfoxide. Langmuir 2019, 35 (20), 6640-6649 DOI: 10.1021/acs.langmuir.9b00670. Wei, B.; Zhao, Y.; Wei, Y.; Yao, J.; Chen, X.; Shao, Z. Morphology and Properties of a New Biodegradable Material Prepared from Zein and Poly(butylene adipate-terephthalate) by Reactive Blending. ACS Omega 2019, 4 (3), 5609-5616 DOI: 10.1021/acsomega.9b00210. Dong, T.; Mi, R.; Wu, M.; Zhong, N.; Zhao, X.; Chen, X.; Shao, Z. The regenerated silk fibroin hydrogel with designed architecture bioprinted by its microhydrogel. J Mater Chem B 2019, 7 (27), 4328-4337 DOI: 10.1039/C9TB00783K. Lin, Q.; Yang, Y.; Ma, Y.; Zhang, R.; Wang, J.; Chen, X.; Shao, Z. Bandgap Engineered Polypyrrole–Polydopamine Hybrid with Intrinsic Raman and Photoacoustic Imaging Contrasts. Nano Lett 2018, 18 (12), 7485-7493 DOI: 10.1021/acs.nanolett.8b02901. Liu, J.; He, T.; Fang, G.; Wang, R.; Kamoun, E. A.; Yao, J.; Shao, Z.; Chen, X. Environmentally responsive composite films fabricated using silk nanofibrils and silver nanowires. J Mater Chem C 2018, 6 (47), 12940-12947 DOI: 10.1039/C8TC04549F. Yao, M.; Su, D.; Wang, W.; Chen, X.; Shao, Z. Fabrication of Air-Stable and Conductive Silk Fibroin Gels. Acs Appl Mater Inter 2018, 10 (44), 38466-38475 DOI: 10.1021/acsami.8b14521. Liu, J.; Li, Z.; Lin, Q.; Jiang, X.; Yao, J.; Yang, Y.; Shao, Z.; Chen, X. A Robust, Resilient, and Multi-Functional Soy Protein-Based Hydrogel. Acs Sustain Chem Eng 2018, 6 (11), 13730-13738 DOI: 10.1021/acssuschemeng.8b01450. Han, Y.; Ling, S.; Qi, Z.; Shao, Z.; Chen, X. Application of far-infrared spectroscopy to the structural identification of protein materials. Physical Chemistry Chemical Physics 2018, 20 (17), 11643-11648 DOI: 10.1039/C8CP00802G. Wen, J.; Yao, J.; Chen, X.; Shao, Z. Silk Fibroin Acts as a Self-Emulsifier to Prepare Hierarchically Porous Silk Fibroin Scaffolds through Emulsion–Ice Dual Templates. ACS Omega 2018, 3 (3), 3396-3405 DOI: 10.1021/acsomega.7b01874. Wang, Y.; Wen, J.; Peng, B.; Hu, B.; Chen, X.; Shao, Z. Understanding the Mechanical Properties and Structure Transition of Antheraea pernyi Silk Fiber Induced by Its Contraction. Biomacromolecules 2018, 19 (6), 1999-2006 DOI: 10.1021/acs.biomac.7b01691. Wu, M.; Yang, W.; Chen, S.; Yao, J.; Shao, Z.; Chen, X. Size-controllable dual drug-loaded silk fibroin nanospheres through a facile formation process. J Mater Chem B 2018, 6 (8), 1179-1186 DOI: 10.1039/C7TB03113K. Li, Z.; Peng, H.; Liu, J.; Tian, Y.; Yang, W.; Yao, J.; Shao, Z.; Chen, X. Plant Protein-Directed Synthesis of Luminescent Gold Nanocluster Hybrids for Tumor Imaging. Acs Appl Mater Inter 2018, 10 (1), 83-90 DOI: 10.1021/acsami.7b13088. Fang, G.; Tang, Y.; Qi, Z.; Yao, J.; Shao, Z.; Chen, X. Precise correlation of macroscopic mechanical properties and microscopic structures of animal silks—using Antheraea pernyi silkworm silk as an example. J Mater Chem B 2017, 5 (30), 6042-6048 DOI: 10.1039/C7TB01638G. Su, D.; Yao, M.; Liu, J.; Zhong, Y.; Chen, X.; Shao, Z. Enhancing Mechanical Properties of Silk Fibroin Hydrogel through Restricting the Growth of β-Sheet Domains. Acs Appl Mater Inter 2017, 9 (20), 17489-17498 DOI: 10.1021/acsami.7b04623. Li, Z.; Yang, Y.; Yao, J.; Shao, Z.; Chen, X. A facile fabrication of silk/MoS2 hybrids for Photothermal therapy. Materials Science and Engineering: C 2017, 79, 123-129 DOI:https://doi.org/10.1016/j.msec.2017.05.010. Liu, J.; Su, D.; Yao, J.; Huang, Y.; Shao, Z.; Chen, X. Soy protein-based polyethylenimine hydrogel and its high selectivity for copper ion removal in wastewater treatment. J Mater Chem A 2017, 5 (8), 4163-4171 DOI: 10.1039/C6TA10814H. Mi, R. X.; Liu, Y. X.; Chen, X.; Shao, Z. Z., Structure and properties of various hybrids fabricated by silk nanofibrils and nanohydroxyapatite. Nanoscale 2016, 8, (48), 20096-20102. Cao, H.; Yang, Y.; Chen, X.; Shao, Z., Intelligent Janus nanoparticles for intracellular real-time monitoring of dual drug release. Nanoscale 2016, 8, (12), 6754-6760. Su, D. H.; Jiang, L. B.; Chen, X.; Dong, J.; Shao, Z. Z., Enhancing the Gelation and Bioactivity of Injectable Silk Fibroin Hydrogel with Laponite Nanoplatelets. Acs Appl Mater Inter 2016, 8, (15), 9619-9628. Yang, W. H.; Shao, Z. Z.; Chen, X., Silk protein nanospheres for paclitaxel/doxorubicin synergistic drug delivery. Nanomedicine-Nanotechnology Biology and Medicine 2016, 12, (2), 554-554. Li, Z.; Zheng, Z.; Yang, Y.; Fang, G.; Yao, J.; Shao, Z.; Chen, X., Robust Protein Hydrogels from Silkworm Silk. Acs Sustain Chem Eng 2016, 4, (3), 1500-1506. Ling, S. J.; Liang, H. Y.; Li, Z.; Ma, L.; Yao, J. R.; Shao, Z. Z.; Chen, X., Soy protein-directed one-pot synthesis of gold nanomaterials and their functional conductive devices. J Mater Chem B 2016, 4, (21), 3643-3650. Fang, G. Q.; Sapru, S.; Behera, S.; Yao, J. R.; Shao, Z. Z.; Kundu, S. C.; Chen, X., Exploration of the tight structural-mechanical relationship in mulberry and non-mulberry silkworm silks. J Mater Chem B 2016, 4, (24), 4337-4347. Lu, S.; Yang, Y.; Yao, J.; Shao, Z.; Chen, X., Exploration of the nature of a unique natural polymer-based thermosensitive hydrogel. Soft Matter 2016, 12, (2), 492-9. Zhang, Z. D.; Liu, Y. X.; Chen, X.; Shao, Z. Z., Multi-responsive polyethylene-polyamine/gelatin hydrogel induced by non-covalent interactions. Rsc Adv 2016, 6, (54), 48661-48665. Jiang, X. J.; Li, Z.; Yao, J. R.; Shao, Z. Z.; Chen, X., One-step synthesis of soy protein/graphene nanocomposites and their application in photothermal therapy. Mat Sci Eng C-Mater 2016, 68, 798-804. Fang, G. Q.; Yang, Y. H.; Yao, J. R.; Shao, Z. Z.; Chen, X., Formation of different gold nanostructures by silk nanofibrils. Mat Sci Eng C-Mater 2016, 64, 376-382. Liu, W.; Wang, Y.; Yao, J. R.; Shao, Z.; Chen, X., Tamoxifen-loaded silk fibroin electrospun fibers. Mater Lett 2016, 178, 31-34. Zhang, C.; Chen, X.; Shao, Z., Sol-Gel Transition of Regenerated Silk Fibroins in Ionic Liquid/Water Mixtures. Acs Biomaterials-Science & Engineering 2016, 2, (1), 12-18. Fang, G. Q.; Huang, Y. F.; Tang, Y. Z.; Qi, Z. M.; Yao, J.; Shao, Z. Z.; Chen, X., Insights into Silk Formation Process: Correlation of Mechanical Properties and Structural Evolution during Artificial Spinning of Silk Fibers. Acs Biomaterials Science & Engineering 2016, 2, (11), 1992-2000.