个人简介

Degrees PhD, University of Szeged, Hungary

研究领域

Organic/Green Chemistry

Green chemistry — solid acid catalysis, metal-catalyzed enantioselective heterogeneous catalytic hydrogenations, microwave-assisted synthesis, asymmetric organocatalysis. Organofluorine chemistry Medicinal chemistry — Self-assembly inhibition of amyloid b, Inhibition of acetylcholinesterase, Synthesis of new antibiotics

近期论文

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S. Bag, R. Tulsan, A. Sood, H. Cho, H. Redjeb, W. Zhou, H. LeVine III, B. Török, M. Török, Sulfonamides as Multi-functional Agents for Alzheimer’s Disease. Bioorg. Med. Chem. Lett. 2014 (in press) H. Cho, R. Madden, B. Nisanci, B. Török, The Paal-Knorr reaction revisited. A catalyst and solvent-free synthesis of underivatized and N-substituted pyrroles. Green Chem. 2014 (in press) C. Schäfer, S. C. Mhadgut, N. Kugyela, M. Török, B. Török, Proline Induced Enantioselective Heterogeneous Catalytic Hydrogenation of Isophorone on Basic Polymer Supported Pd Catalysts. Catal. Sci. Tech. 2014 (in press) DOI: 10.1039/C4CY00954A H. Cho, F. Török, B. Török, Energy Efficiency of Heterogeneous Catalytic Microwave-assisted Organic Reactions. Green Chem. 2014, 16, 3623-3634. S. Chang, B. Török, K. A. Stieglitz, The role of phospholipase D enzyme(s) in modulating cell signaling: Implications for cancer drug development. Curr. Bioact. Comp. 2014, 10, 124-130. S. Bellinger-Buckley, T.-C. Chang, D. Schweinfurth, S. Bag, W. Zhou, B. Török, B. Sarkar, M.-K. Tsai, J. Rochford, Exploring the non-innocent character of electron rich p-extended 8-oxyquinolate ligands in ruthenium(II) bipyridyl complexes. Inorg. Chem. 2014, 53, 5556-5567. A. Kulkarni, P. Quang, V. Curry, R. Keyes, W. Zhou, H. Cho, J. Baffoe, B. Török, K. Stieglitz, 1,3-disubstituted-4-aminopyrazolo [3, 4-d] pyrimidines, a new class of potent inhibitors for Phopholipase D Chem. Biol. Drug Design 2014, 84, 270-281. S. M. Landge, B. Török: Stereoselective Synthesis of a-fluoro-b-trifluoromethyl-a,b-unsaturated Esters by Horner-Wadsworth-Emmons Coupling. Lett. Org. Chem. 2014, 11, 374-379. A. Solan, B. Nişanci, M. Belcher, J. Young, C. Schäfer, K. A. Wheeler, B. Török, R. Dembinski, Catalyst-free chemo/regio/stereo-selective amination of alk-3-ynones. Synthesis of 1,5-benzodiazepines and 3-amino-2-alkenones. Green Chem. 2014, 16, 1120-1124. S. Bag, S. Ghosh, R. Tulsan, A. Sood, W. Zhou, C. Schifone, M. Foster, H. LeVine III, B. Török, M. Török, Design, Synthesis and Biological Activity of Multifunctional a,b-Unsaturated Carbonyl Scaffolds for Alzheimer’s Disease. Bioorg. Med. Chem. Lett. 2013 23, 2614–2618. B. Török, A. Sood, S. Bag, R. Tulsan, S. Ghosh, D. Borkin, A. Kennedy, M. Melanson, R. Madden, W. Zhou, H. LeVine III, M. Török Diaryl Hydrazones as Multifunctional Inhibitors of Amyloid Self-Assembly. Biochemistry 2013, 52, 1137-1148 . H. Cho, F. Török, B. Török, Selective Reduction of Condensed N-heterocycles Using Water as Solvent and Hydrogen Source. Org. Biomol. Chem. 2013, 11, 1209-1215. B. Török, S. Bag, M. Sarkar, S. Dasgupta, M. Török Structural Features of Small Molecule Amyloid-Beta Self-Assembly Inhibitors. Curr. Bioact. Comp. 2013 9, 37-63. H. Jeong, J. C. Axtell, B. Török, R. R. Schrock, P. Muller: Syntheses of Tungsten tert-Butylimido and Adamantylimido Alkylidene Complexes Employing Pyridinium Chloride As the Acid. Organometallics 2012, 31, 6522-6525. Tomin, A. Lazarev, M. P. Bere, H. Redjeb, B. Török: Selective Reduction of Ketones using Water as a Hydrogen Source under High Hydrostatic Pressure. Org. Biomol. Chem. 2012, 10, 7321-7326. D. A. Borkin, M. Puscau, A. Carlson, K. A. Wheeler, B. Török, R. Dembinski: Synthesis of diversely 1,3,5-substituted pyrazoles via 5-exo-dig cyclization. Org. Biomol. Chem. 2012, 10, 4505 - 4508. B. Török, A. Sood, S. Bag, A. Kulkarni, D. Borkin, E. Lawler, S. Dasgupta, S. Landge, M. Abid, W. Zhou, M. Foster, H. LeVine III, M. Török: Structure-activity relationship of organofluorine inhibitors of amyloid-beta self-assembly. ChemMedChem, 2012, 7, 910-919. G. K. S. Prakash, K. E. Glinton, C. Panja, L. Gurung, P. T. Battamack, B. Török, T. Mathew, G. A. Olah: Thermocontrolled benzylimine–benzaldimine rearrangement over Nafion-H catalysts for efficient entry into a-trifluoromethylbenzylamines. Tetrahedron Lett. 2012, 53, 607-611. A. Tomin, S. Bag, B. Török: Direct C-H bond activation reactions. in Green Techniques for Organic Synthesis and Medicinal Chemistry (Eds. W. Zhang, B. C. Cue), Chp.4 Wiley, Chichester, 2012, pp 69-97. A. Daştan, A. Kulkarni, B. Török: Environmentally Benign Synthesis of Heterocyclic Compounds by Combined Microwave-Assisted Heterogeneous Catalytic Approaches. Green Chem. 2012, 14, 17-37.