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House, R. P., Pozzuto, M., Patel, P., Dulyaninova, N. G., Li, Z. H., Zencheck, W. D., Vitolo, M. I., Weber, D. J., and Bresnick, A. R. Two Functional S100A4 Monomers Are Necessary for Regulating NonmuscleMyosin-IIA and HCT116 Cell Invasion (2011) Biochemistry, 50, 6920-6932.
Yamaguchi, N., Prosser, B.L., Ghassemi, F., Xu, L., Pasek, D.A., Eu, J.P., Hernández-Ochoa, E.O., Cannon, B.R., Wilder, P.T., Lovering, R.M., Weber, D.J., Melzer, W., Schneider, M.F., and Meissner, G. Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1 (2011) Am. J. Physiol. Cell, 300, 998-1012. PMC Journal - In Process.
Malashkevich, V., Dulyaninova, N.G., Liriano, M.A., Varney, K.M., Knight, D., Brenowitz, M., Weber, D.J., Almo, S.C., and Bresnick, A.R. Unique mechanism of S100A4 inhibition: Trifluoperazine- induced protein oligomerization (2010) Proc. Nat. Acad. Sci., 107, 8605-8610. PMC Journal - In Process.
Lin, J., Yang, Q., Wilder, P.T., Carrier, F., and Weber, D.J. The calcium-binding protein S100B down- regulates p53 and apoptosis in malignant melanoma (2010) J. Biol. Chem., 285, 27487-27498. PMC Journal - In Process
Wilder, P.T., Charpentier, T.H., Liriano, M.A., Gianni, K., Varney, K.M., Pozharski, E., Coop, A., Toth, E.A., MacKerell, A.D. and Weber, D.J.In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction (2010) Int. J. High-Throughput Screening, 1, 109-126.NIHMSID:NIHMS199963.
Smith, J., Steward, B.J., Glaysher, S., Peregrin, K., Knight, L.A., Weber, D.J., and Cree, I.A. The effects of pentamidine on melanoma ex vivo (2010) Anti-Cancer Drugs, 21, 181-185.PMCID: PMC2866106.
Zimmer, D.Z. and Weber, D.J. The calcium-dependent interaction of S100B with its protein targets (2010) Cardiovasc. Psych. and Neurol., 2010, 1-17.
Charpentier, T.H., Thompson, L.E., Liriano, M.A., Varney, K.M., Wilder, P.T., Pozharski, E., Toth, E.A., and Weber, D.J. The effect of the CapZ peptide (TRTK-12) binding to Ca2+-S100B as examined by NMR and X-ray crystallography (2010) J. Mol. Biol., 396, 1227-1243. NIHMSID:NIHMS177816. PMCID: PMC2843395.
Malashkevich, V., Dulyaninova, N.G., Liriano, M.A., Varney, K.M., Knight, D., Brenowitz, M., Weber, D.J., Almo, S.C., and Bresnick, A.R. Unique mechanism of S100A4 inhibition: Trifluoperazine-induced protein oligomerization (2010) Proc. Nat. Acad. Sci., 107, 8605-8610. PMC Journal - In Process.
Gilquin, B., Cannon, B.R., Hubstenberger, A., Moulouel, B., Falk, E., Merle, N., Assard, N., Kieffer, S., Rousseau, D., Wilder, P.T., Weber, D.J., Baudier, J. The calcium-dependent interaction between S100B and the mitochondrial 1 AAA-ATPase 2 ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A (2010), Mol. Cell Biol., 30, 2724-2736. PMC Journal - In Process.
Weiss, M.B., Vitolo, M.I., Mohseni, M., Rosen, D.M., Denmeade, S.R., Park, B.H., Weber, D.J., and Bachman, K.E. Somatic cell knockout of p53 in human mammary epithelial cells causes chromosomal instability (2010) Oncogene, 29, 4715-4724. PMC Journal - In Process.
Lin, J., Yang, Q., Wilder, P.T., Carrier, F., and Weber, D.J. The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma (2010) J. Biol. Chem., 285, 27487-27498. PMC Journal - In Process.
Wilder, P.T., Charpentier, T.H., Liriano, M.A., Gianni, K., Varney, K.M., Pozharski, E., Coop, A., Toth, E.A., MacKerell, A.D. and Weber, D.J. In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction (2010) Int. J. High-Throughput Screening, 1, 109-126. NIHMSID:NIHMS199963.
Zimmer, D.Z. and Weber, D.J. The calcium-dependent interaction of S100B with its protein targets (2010) Cardiovasc. Psych. and Neurol., 2010, 1-17.
Smith, J., Steward, B.J., Glaysher, S., Peregrin, K., Knight, L.A., Weber, D.J., and Cree, I.A. The effects of pentamidine on melanoma ex vivo (2010) Anti-Cancer Drugs, 21, 181-185. NIHMSID:NIHMS189914.
Wright, N.T., Cannon, B.R., Wilder, P.T., Morgan, M.T., Varney, K.M., Zimmer, D.B., and Weber, D.J. Solution structure of S100A1 bound to the CapZ peptide TRTK-12 (2009) J. Mol. Biol., 386, 1265-1277. (NIHMSID:NIHMS120897)
Charpentier, T.H., Wilder, P.T., Liriano, M.A., Varney, K.M., Zhong, S., Coop, A., Pozharski, E., MacKerell, A.D., Toth, E.A., and Weber, D.J. Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance (NMR) and X-ray crystallography (2009) Biochemistry, 48, 6202-6212.
Vitolo, M.I., Weiss, M.B., Szmacinski, M., Tahir, K., Waldman, T., Park, B.H., Martin, S.S., Weber, D.J., and Bachman, K.E. Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells (2009) Cancer Res., in press.
Wright, N.T., Cannon, B.R., Zimmer, D., and Weber, D.J. S100A1: Structure, function, and therapeutic potential (2009) Curr. Chem. Biol., 3, 138-145. (NIHMSID:NIHMS121910)
Matthews, M.M., Weber, D.J., Shapiro, P.S., Coop, A., and MacKerell, Jr., A.D. Inhibition of protein-protein interactions with low molecular weight compounds (2009) Curr. Trends Med. Chem., in press.